Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [559-660] (Homo sapiens) | BDBM23208 ((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Guangzhou University of Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of PDE4 (unknown origin) | J Med Chem 63: 3370-3380 (2020) Article DOI: 10.1021/acs.jmedchem.0c00060 BindingDB Entry DOI: 10.7270/Q20Z76QT | |||||||||||
More data for this Ligand-Target Pair |