BindingDB PrimarySearch

Found 7 hits of ic50 for UniProtKB: P16390
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 3 (Mus musculus)	BDBM50115772 (CHEMBL3609094) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0230	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-ChTX from mouse Kv1.3 after 20 mins by scintillation counting analysis				J Med Chem 58: 6784-802 (2015) Article DOI: 10.1021/acs.jmedchem.5b00495 BindingDB Entry DOI: 10.7270/Q22V2HWG
Amgen Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Mus musculus)	BDBM50083523 ((1-Benzyl-1H-quinolin-4-ylidene)-pentyl-amine \| CH...) Show SMILES CCCCC\N=c1/ccn(Cc2ccccc2)c2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
University of Kiel Curated by ChEMBL					Assay Description Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uM				J Med Chem 44: 1249-56 (2001) BindingDB Entry DOI: 10.7270/Q2TH8KZV
University of Kiel Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Mus musculus)	BDBM50098785 (4-Benzhydryloxymethyl-1-[3-(4-methoxy-phenyl)-prop...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of Kiel Curated by ChEMBL					Assay Description Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uM				J Med Chem 44: 1249-56 (2001) BindingDB Entry DOI: 10.7270/Q2TH8KZV
University of Kiel Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Mus musculus)	BDBM50098782 (2-Isopropyl-8-methoxy-5-methyl-5H-furo[3,2-c]quino...) Show SMILES COc1ccc2n(C)c(=O)c3cc(oc3c2c1)C(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kiel Curated by ChEMBL					Assay Description Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uM				J Med Chem 44: 1249-56 (2001) BindingDB Entry DOI: 10.7270/Q2TH8KZV
University of Kiel Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Mus musculus)	BDBM50098781 (9-Methoxy-2,2,6-trimethyl-2,6-dihydro-pyrano[3,2-c...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kiel Curated by ChEMBL					Assay Description Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uM				J Med Chem 44: 1249-56 (2001) BindingDB Entry DOI: 10.7270/Q2TH8KZV
University of Kiel Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Mus musculus)	BDBM50098784 (9-Methoxy-2,2,6-trimethyl-2,3,4,6-tetrahydro-pyran...) Show SMILES COc1ccc2n(C)c(=O)c3CCC(C)(C)Oc3c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kiel Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 expressed in L929 cells				J Med Chem 44: 1249-56 (2001) BindingDB Entry DOI: 10.7270/Q2TH8KZV
University of Kiel Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Mus musculus)	BDBM50098783 (4,6,7-Trimethoxy-furo[2,3-b]quinoline \| CHEMBL2787...) Show SMILES COc1cc2nc3occc3c(OC)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kiel Curated by ChEMBL					Assay Description Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uM				J Med Chem 44: 1249-56 (2001) BindingDB Entry DOI: 10.7270/Q2TH8KZV
University of Kiel Curated by ChEMBL					More data for this Ligand-Target Pair