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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for UniProtKB: P43118   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin F2-alpha receptor


(Rattus norvegicus)
BDBM520995
PNG
((+)-5-[({6-Bromo-3-methyl-2-[(2H8)pyrrolidin-1-yl]...)
Show SMILES Cc1c(nc2ccc(Br)cc2c1C(=O)NC[C@H](CCC(O)=O)c1ccccc1Cl)N1CCCC1 |r|
PDB

KEGG

UniProtKB/SwissProt

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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 11n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at rat FPR stably expressed in CHO cells assessed as inhibition of PGF2alpha-induced calcium flux preincubated for 10 mins follow...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c00834
BindingDB Entry DOI: 10.7270/Q2FJ2MC9
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Rattus norvegicus)
BDBM520995
PNG
((+)-5-[({6-Bromo-3-methyl-2-[(2H8)pyrrolidin-1-yl]...)
Show SMILES Cc1c(nc2ccc(Br)cc2c1C(=O)NC[C@H](CCC(O)=O)c1ccccc1Cl)N1CCCC1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 52n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at FPR in Wistar rat assessed as inhibition of PGF2alpha-induced uterus contraction


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c00834
BindingDB Entry DOI: 10.7270/Q2FJ2MC9
More data for this
Ligand-Target Pair