Compile Data Set for Download or QSAR

Found 13 hits of ic50 for UniProtKB: P53539   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein FosB (Homo sapiens)	BDBM29615 (6-methoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]qui...) Show SMILES COc1cccc2C3C=CCC3C(Nc12)C(O)=O |c:8| Show InChI InChI=1S/C14H15NO3/c1-18-11-7-3-6-9-8-4-2-5-10(8)13(14(16)17)15-12(9)11/h2-4,6-8,10,13,15H,5H2,1H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of recombinant Hi6-tagged deltaFOSB (unknown origin) expressed in insect cells interaction with TAMRA labeled 5'-GTCGGTGACTCAAAACA-3' AP1 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127300 BindingDB Entry DOI: 10.7270/Q27084Z1
					More data for this Ligand-Target Pair
Protein FosB (Homo sapiens)	BDBM50544070 (CHEMBL4640716) Show SMILES COc1cc(OC)c2c(nc3c(OC)cccc3c2c1)C1CCNCC1 Show InChI InChI=1S/C21H24N2O3/c1-24-14-11-16-15-5-4-6-17(25-2)21(15)23-20(13-7-9-22-10-8-13)19(16)18(12-14)26-3/h4-6,11-13,22H,7-10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of recombinant Hi6-tagged deltaFOSB (unknown origin) expressed in insect cells interaction with TAMRA labeled 5'-GTCGGTGACTCAAAACA-3' AP1 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127300 BindingDB Entry DOI: 10.7270/Q27084Z1
					More data for this Ligand-Target Pair
Protein FosB (Homo sapiens)	BDBM50544062 (CHEMBL4640911) Show SMILES COc1cccc2C3C=CCC3C(Nc12)C(=O)Nc1ccccc1 |c:8| Show InChI InChI=1S/C20H20N2O2/c1-24-17-12-6-11-15-14-9-5-10-16(14)19(22-18(15)17)20(23)21-13-7-3-2-4-8-13/h2-9,11-12,14,16,19,22H,10H2,1H3,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of recombinant Hi6-tagged deltaFOSB (unknown origin) expressed in insect cells interaction with TAMRA labeled 5'-GTCGGTGACTCAAAACA-3' AP1 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127300 BindingDB Entry DOI: 10.7270/Q27084Z1
					More data for this Ligand-Target Pair
Protein FosB (Homo sapiens)	BDBM50544063 (CHEMBL4642507) Show SMILES COc1cccc2C3C=CCC3C(CO)Nc12 |c:8| Show InChI InChI=1S/C14H17NO2/c1-17-13-7-3-6-11-9-4-2-5-10(9)12(8-16)15-14(11)13/h2-4,6-7,9-10,12,15-16H,5,8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of recombinant Hi6-tagged deltaFOSB (unknown origin) expressed in insect cells interaction with TAMRA labeled 5'-GTCGGTGACTCAAAACA-3' AP1 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127300 BindingDB Entry DOI: 10.7270/Q27084Z1
					More data for this Ligand-Target Pair
Protein FosB (Homo sapiens)	BDBM50544064 (CHEMBL4636518) Show SMILES COc1cccc2C3C=CCC3C(N(C(C)=O)c12)C(O)=O |c:8| Show InChI InChI=1S/C16H17NO4/c1-9(18)17-14-11(7-4-8-13(14)21-2)10-5-3-6-12(10)15(17)16(19)20/h3-5,7-8,10,12,15H,6H2,1-2H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of recombinant Hi6-tagged deltaFOSB (unknown origin) expressed in insect cells interaction with TAMRA labeled 5'-GTCGGTGACTCAAAACA-3' AP1 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127300 BindingDB Entry DOI: 10.7270/Q27084Z1
					More data for this Ligand-Target Pair
Protein FosB (Homo sapiens)	BDBM50544071 (CHEMBL4648025) Show SMILES COc1cc(OC)c2c(nc3c(OC)cccc3c2c1)C1CCN(CC1)C(C)=O Show InChI InChI=1S/C23H26N2O4/c1-14(26)25-10-8-15(9-11-25)22-21-18(12-16(27-2)13-20(21)29-4)17-6-5-7-19(28-3)23(17)24-22/h5-7,12-13,15H,8-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of recombinant Hi6-tagged deltaFOSB (unknown origin) expressed in insect cells interaction with TAMRA labeled 5'-GTCGGTGACTCAAAACA-3' AP1 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127300 BindingDB Entry DOI: 10.7270/Q27084Z1
					More data for this Ligand-Target Pair
Protein FosB (Homo sapiens)	BDBM50544066 (CHEMBL4648918) Show SMILES CCOC(=O)c1nc2c(C)cccc2c2CCCc12 Show InChI InChI=1S/C16H17NO2/c1-3-19-16(18)15-13-9-5-7-11(13)12-8-4-6-10(2)14(12)17-15/h4,6,8H,3,5,7,9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of recombinant Hi6-tagged deltaFOSB (unknown origin) expressed in insect cells interaction with TAMRA labeled 5'-GTCGGTGACTCAAAACA-3' AP1 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127300 BindingDB Entry DOI: 10.7270/Q27084Z1
					More data for this Ligand-Target Pair
Protein FosB (Homo sapiens)	BDBM50544067 (CHEMBL4648459) Show SMILES Cc1cccc2c3CCCc3c(nc12)C(O)=O Show InChI InChI=1S/C14H13NO2/c1-8-4-2-6-10-9-5-3-7-11(9)13(14(16)17)15-12(8)10/h2,4,6H,3,5,7H2,1H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of recombinant Hi6-tagged deltaFOSB (unknown origin) expressed in insect cells interaction with TAMRA labeled 5'-GTCGGTGACTCAAAACA-3' AP1 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127300 BindingDB Entry DOI: 10.7270/Q27084Z1
					More data for this Ligand-Target Pair
Protein FosB (Homo sapiens)	BDBM50544068 (CHEMBL4638737) Show SMILES COc1cc(OC)c2c(nc3c(OC)cccc3c2c1)C(O)=O Show InChI InChI=1S/C17H15NO5/c1-21-9-7-11-10-5-4-6-12(22-2)15(10)18-16(17(19)20)14(11)13(8-9)23-3/h4-8H,1-3H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of recombinant Hi6-tagged deltaFOSB (unknown origin) expressed in insect cells interaction with TAMRA labeled 5'-GTCGGTGACTCAAAACA-3' AP1 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127300 BindingDB Entry DOI: 10.7270/Q27084Z1
					More data for this Ligand-Target Pair
Protein FosB (Homo sapiens)	BDBM50544069 (CHEMBL4637145) Show SMILES COc1cc(OC)c2c(nc3c(OC)cccc3c2c1)C1CCN(CC1)C(=O)OC(C)(C)C Show InChI InChI=1S/C26H32N2O5/c1-26(2,3)33-25(29)28-12-10-16(11-13-28)23-22-19(14-17(30-4)15-21(22)32-6)18-8-7-9-20(31-5)24(18)27-23/h7-9,14-16H,10-13H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of recombinant Hi6-tagged deltaFOSB (unknown origin) expressed in insect cells interaction with TAMRA labeled 5'-GTCGGTGACTCAAAACA-3' AP1 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127300 BindingDB Entry DOI: 10.7270/Q27084Z1
					More data for this Ligand-Target Pair
Protein FosB (Homo sapiens)	BDBM50544061 (CHEMBL4634410) Show SMILES CNC(=O)C1Nc2c(OC)cccc2C2C=CCC12 |c:16| Show InChI InChI=1S/C15H18N2O2/c1-16-15(18)14-11-6-3-5-9(11)10-7-4-8-12(19-2)13(10)17-14/h3-5,7-9,11,14,17H,6H2,1-2H3,(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of recombinant Hi6-tagged deltaFOSB (unknown origin) expressed in insect cells interaction with TAMRA labeled 5'-GTCGGTGACTCAAAACA-3' AP1 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127300 BindingDB Entry DOI: 10.7270/Q27084Z1
					More data for this Ligand-Target Pair
Protein FosB (Homo sapiens)	BDBM50544060 (CHEMBL4635546) Show SMILES CCOC(=O)C1Nc2c(OC)cccc2C2C=CCC12 |c:17| Show InChI InChI=1S/C16H19NO3/c1-3-20-16(18)15-12-7-4-6-10(12)11-8-5-9-13(19-2)14(11)17-15/h4-6,8-10,12,15,17H,3,7H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of recombinant Hi6-tagged deltaFOSB (unknown origin) expressed in insect cells interaction with TAMRA labeled 5'-GTCGGTGACTCAAAACA-3' AP1 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127300 BindingDB Entry DOI: 10.7270/Q27084Z1
					More data for this Ligand-Target Pair
Protein FosB (Homo sapiens)	BDBM50544065 (CHEMBL4646481) Show SMILES COc1cccc2C3CCCC3C(Nc12)C(O)=O Show InChI InChI=1S/C14H17NO3/c1-18-11-7-3-6-9-8-4-2-5-10(8)13(14(16)17)15-12(9)11/h3,6-8,10,13,15H,2,4-5H2,1H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of recombinant Hi6-tagged deltaFOSB (unknown origin) expressed in insect cells interaction with TAMRA labeled 5'-GTCGGTGACTCAAAACA-3' AP1 ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127300 BindingDB Entry DOI: 10.7270/Q27084Z1
					More data for this Ligand-Target Pair