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Compile Data Set for Download or QSAR

Found 9 hits of ic50 for UniProtKB: P35918   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Mus musculus)
BDBM50613385
PNG
(CHEMBL5288744)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a 37n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Mus musculus)
BDBM9503
PNG
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1
Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)
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CHEMBL
MCE
PC cid
PC sid
PDB
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Similars

n/an/a 55n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Mus musculus)
BDBM4814
PNG
(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C
Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-
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n/an/a 73n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Mus musculus)
BDBM50613383
PNG
(CHEMBL5280119)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 125n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Mus musculus)
BDBM50270439
PNG
(CHEMBL4104297)
Show SMILES Nc1nccc(Oc2ccc3c(cccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)n1
Show InChI InChI=1S/C22H15F3N4O2/c23-22(24,25)14-4-2-5-15(12-14)28-20(30)18-6-1-3-13-11-16(7-8-17(13)18)31-19-9-10-27-21(26)29-19/h1-12H,(H,28,30)(H2,26,27,29)
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n/an/a 165n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Mus musculus)
BDBM4851
PNG
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
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n/an/a 270n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Mus musculus)
BDBM50613384
PNG
(CHEMBL5276611)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 320n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Mus musculus)
BDBM50270425
PNG
(CHEMBL4080062)
Show SMILES OCc1cc(Oc2ccc3c(cccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1
Show InChI InChI=1S/C23H16F3N3O3/c24-23(25,26)15-4-2-5-16(10-15)29-22(31)20-6-1-3-14-9-18(7-8-19(14)20)32-21-11-17(12-30)27-13-28-21/h1-11,13,30H,12H2,(H,29,31)
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n/an/a 1.50E+3n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Mus musculus)
BDBM50568078
PNG
(CHEMBL4865518)
Show SMILES [Na;v0+].[H][C@]12[#6@H](-[#6][C@@]3([#6])[#6]4=[#6]-[#6]-[#6]5C([#6])([#6])[C@]([H])([#6]-[#6][C@]5([#6])[C@]4([H])[#6]-[#6][C@]13[#6](=O)-[#8][C@@]2([#6])[#6]-[#6]-[#6]-[#6](-[#6])=[#6])[#8]-[#6@@H]1-[#8]-[#6]-[#6@@H](-[#8]S([#8-])(=O)=O)-[#6@H](-[#8])[C@@]1([H])[#8]-[#6@@H]-1-[#8]-[#6@H](-[#6])-[#6@@H](-[#8][C@]2([H])[#8]-[#6]-[#6@@H](-[#8])-[#6@H](-[#8][C@]3([H])[#8]-[#6@H](-[#6]-[#8])-[#6@@H](-[#8])-[#6@H](-[#8]-[#6])-[#6@H]3-[#8])-[#6@H]2-[#8])-[#6@H](-[#8])-[#6@H]-1-[#8])-[#8]-[#6](-[#6])=O |r,t:6|
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Article
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of VEGFR2 in mouse NIH/3T3 cells assessed as reduction of VEGF-stimulated phosphorylation


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116188
BindingDB Entry DOI: 10.7270/Q2WH2TRD
More data for this
Ligand-Target Pair