Compile Data Set for Download or QSAR

Found 8 hits of ec50 for UniProtKB: P30532   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2 (Homo sapiens (Human))	BDBM50445605 (CHEMBL3104001) Show SMILES [O-][N+](=O)c1cccc(c1)-c1nc(no1)-c1cccnc1 Show InChI InChI=1S/C13H8N4O3/c18-17(19)11-5-1-3-9(7-11)13-15-12(16-20-13)10-4-2-6-14-8-10/h1-8H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...				Bioorg Med Chem Lett 24: 674-8 (2014) Article DOI: 10.1016/j.bmcl.2013.11.049 BindingDB Entry DOI: 10.7270/Q2RF5WH9
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2 (Homo sapiens (Human))	BDBM50445612 (CHEMBL3103985) Show SMILES c1cncc(c1)-c1nnn(n1)-c1cccnc1 Show InChI InChI=1S/C11H8N6/c1-3-9(7-12-5-1)11-14-16-17(15-11)10-4-2-6-13-8-10/h1-8H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...				Bioorg Med Chem Lett 24: 674-8 (2014) Article DOI: 10.1016/j.bmcl.2013.11.049 BindingDB Entry DOI: 10.7270/Q2RF5WH9
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2 (Homo sapiens (Human))	BDBM50445611 (CHEMBL3103988) Show SMILES N#Cc1cccc(c1)-c1nc(no1)-c1cccnc1 Show InChI InChI=1S/C14H8N4O/c15-8-10-3-1-4-11(7-10)14-17-13(18-19-14)12-5-2-6-16-9-12/h1-7,9H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	790	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...				Bioorg Med Chem Lett 24: 674-8 (2014) Article DOI: 10.1016/j.bmcl.2013.11.049 BindingDB Entry DOI: 10.7270/Q2RF5WH9
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2 (Homo sapiens (Human))	BDBM50445610 (CHEMBL3104068) Show SMILES c1cncc(c1)-c1noc(n1)-c1cccnc1 Show InChI InChI=1S/C12H8N4O/c1-3-9(7-13-5-1)11-15-12(17-16-11)10-4-2-6-14-8-10/h1-8H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...				Bioorg Med Chem Lett 24: 674-8 (2014) Article DOI: 10.1016/j.bmcl.2013.11.049 BindingDB Entry DOI: 10.7270/Q2RF5WH9
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2 (Homo sapiens (Human))	BDBM50445609 (CHEMBL3103999) Show SMILES Fc1ccc(cc1F)-c1nc(no1)-c1cccnc1 Show InChI InChI=1S/C13H7F2N3O/c14-10-4-3-8(6-11(10)15)13-17-12(18-19-13)9-2-1-5-16-7-9/h1-7H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...				Bioorg Med Chem Lett 24: 674-8 (2014) Article DOI: 10.1016/j.bmcl.2013.11.049 BindingDB Entry DOI: 10.7270/Q2RF5WH9
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2 (Homo sapiens (Human))	BDBM50445608 (CHEMBL3104126) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1nc(no1)-c1cccnc1 Show InChI InChI=1S/C13H8N4O3/c18-17(19)11-5-3-9(4-6-11)13-15-12(16-20-13)10-2-1-7-14-8-10/h1-8H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...				Bioorg Med Chem Lett 24: 674-8 (2014) Article DOI: 10.1016/j.bmcl.2013.11.049 BindingDB Entry DOI: 10.7270/Q2RF5WH9
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2 (Homo sapiens (Human))	BDBM50445607 (CHEMBL3104079) Show SMILES N#Cc1cccc(c1)-n1nnc(n1)-c1cccnc1 Show InChI InChI=1S/C13H8N6/c14-8-10-3-1-5-12(7-10)19-17-13(16-18-19)11-4-2-6-15-9-11/h1-7,9H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...				Bioorg Med Chem Lett 24: 674-8 (2014) Article DOI: 10.1016/j.bmcl.2013.11.049 BindingDB Entry DOI: 10.7270/Q2RF5WH9
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2 (Homo sapiens (Human))	BDBM50445606 (CHEMBL3103983) Show SMILES N#Cc1ccc(cc1)-n1nnc(n1)-c1cccnc1 Show InChI InChI=1S/C13H8N6/c14-8-10-3-5-12(6-4-10)19-17-13(16-18-19)11-2-1-7-15-9-11/h1-7,9H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...				Bioorg Med Chem Lett 24: 674-8 (2014) Article DOI: 10.1016/j.bmcl.2013.11.049 BindingDB Entry DOI: 10.7270/Q2RF5WH9
					More data for this Ligand-Target Pair