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Compile Data Set for Download or QSAR

Found 3 hits of ec50 for UniProtKB: P03431   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RNA-directed RNA polymerase catalytic subunit


(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
BDBM50154375
PNG
(Adenosine receptor agonist, 16 | Ribavirin | Triba...)
Show SMILES NC(=O)c1ncn(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
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MCE
PC cid
PC sid
PDB
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Article
PubMed
n/an/an/an/a 1.60E+4n/an/an/an/a


TBA

Assay Description
Inhibition of RdRP activity in Influenza A virus A/PR/8/34(H1N1) infected in HEK293T cells incubated for 24 hrs by minireplicon based dual luciferase...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113494
BindingDB Entry DOI: 10.7270/Q28056DV
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase catalytic subunit


(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
BDBM50577041
PNG
(CHEMBL4870823)
Show SMILES Cc1cc(-c2ccccc2)n2nc(nc2n1)-c1nc2ccccc2c(=O)o1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.10E+4n/an/an/an/a


TBA

Assay Description
Inhibition of RdRP activity in Influenza A virus A/PR/8/34(H1N1) infected in HEK293T cells incubated for 24 hrs by minireplicon based dual luciferase...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113494
BindingDB Entry DOI: 10.7270/Q28056DV
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase catalytic subunit


(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
BDBM50154375
PNG
(Adenosine receptor agonist, 16 | Ribavirin | Triba...)
Show SMILES NC(=O)c1ncn(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
PDB

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KEGG

UniProtKB/SwissProt

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DrugBank
MCE
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 2.40E+4n/an/an/an/a


TBA

Assay Description
Inhibition of RdRP activity in Influenza A virus A/PR/8/34 (H1N1) infected in HEK293T cells co-transfected with NP/PA/PB1/PB2/pPolI-Flu-ffLuc/pRL-SV4...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112944
BindingDB Entry DOI: 10.7270/Q2Z03CWN
More data for this
Ligand-Target Pair