Compile Data Set for Download or QSAR

Found 24 hits of ic50 for UniProtKB: P36776   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571496 (CHEMBL4876525) Show SMILES CCC[C@@H](NC(=O)c1cnccn1)C(=O)N[C@@H](CCCc1ccccc1)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571500 (CHEMBL4856865) Show SMILES OB(O)[C@H](CCCc1ccccc1)NC(=O)[C@@H](Cc1ccccc1)NC(=O)c1cnccn1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571499 (CHEMBL4864108) Show SMILES OB(O)[C@H](CCc1ccccc1)NC(=O)[C@@H](Cc1ccccc1)NC(=O)c1cnccn1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571493 (CHEMBL4877126) Show SMILES CCCC[C@H](NC(=O)[C@@H](CCC)NC(=O)c1cnccn1)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571492 (CHEMBL4870013) Show SMILES CCC[C@@H](NC(=O)c1oc(C)nc1C)C(=O)N[C@@H](CCCc1ccccc1)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571502 (CHEMBL4862424) Show SMILES CC(C)CCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571501 (CHEMBL4870902) Show SMILES OB(O)[C@H](CCCCCBr)NC(=O)[C@@H](Cc1ccccc1)NC(=O)c1cnccn1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571495 (CHEMBL4876920) Show SMILES CCC[C@@H](NC(=O)c1cnccn1)C(=O)N[C@@H](CCc1ccccc1)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571503 (CHEMBL4850612) Show SMILES OB(O)[C@H](CC1CCCCC1)NC(=O)[C@@H](Cc1ccccc1)NC(=O)c1cnccn1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571508 (CHEMBL4856768) Show SMILES CCCC[C@@H](NC(=O)c1cnccn1)C(=O)N[C@@H](CC(C)C)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571498 (CHEMBL4847335) Show SMILES OB(O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccccc1)NC(=O)c1cnccn1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571497 (CHEMBL4863384) Show SMILES CCC[C@@H](NC(=O)c1cnccn1)C(=O)N[C@@H](CC1CCCCC1)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571505 (CHEMBL4847763) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](CC1CCCCC1)NC(=O)c1cnccn1)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50069989 ((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O |r| Show InChI InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571509 (CHEMBL4861871) Show SMILES CCC[C@@H](NC(=O)c1cnccn1)C(=O)N[C@@H](CC(C)C)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	187	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571512 (CHEMBL4858320) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	253	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571510 (CHEMBL4853599) Show SMILES CC[C@@H](NC(=O)c1cnccn1)C(=O)N[C@@H](CC(C)C)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	408	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571511 (CHEMBL4864045) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)c1cnccn1)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	433	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571507 (CHEMBL4859172) Show SMILES CC(C)C[C@H](NC(=O)[C@H](NC(=O)c1cnccn1)C(C)C)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	546	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571494 (CHEMBL4850826) Show SMILES CCC[C@@H](NC(=O)c1cnccn1)C(=O)N[C@@H](Cc1ccccc1)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	556	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM200228 (AB01275474-01 | cid_24871309) Show SMILES CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O Show InChI InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571506 (CHEMBL4862987) Show SMILES CC(C)C[C@H](NC(=O)[C@H](NC(=O)c1cnccn1)C(C)(C)C)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571513 (CHEMBL1530) Show SMILES CC(C)C[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair
Lon protease homolog, mitochondrial (Homo sapiens)	BDBM50571504 (CHEMBL4854436) Show SMILES CC(C)C[C@H](NC(=O)C(C)(C)NC(=O)c1cnccn1)B(O)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LONP1 (unknown origin) using QXL520-YRGITCSGRQK(5-FAM)-NH2 peptide as substrate incubated for 50 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02152 BindingDB Entry DOI: 10.7270/Q25Q50WZ
					More data for this Ligand-Target Pair