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Compile Data Set for Download or QSAR

Found 29 hits of ic50 for UniProtKB: P18584   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50603188
PNG
(CHEMBL5195583)
Show SMILES CC(C)C(NC(=O)[C@@H]1C[C@H](CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)OC(C)=O)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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UniChem
Article
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n/an/a 3.86E+3n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50577901
PNG
(CHEMBL4872003)
Show SMILES CCC(C)C(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)C(C)(C)C)C(C)(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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n/an/a 4.57E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50524817
PNG
(CHEMBL4583962)
Show SMILES CC(C)C(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
Show InChI InChI=1S/C32H46N3O7P/c1-22(2)28(43(39,41-23-16-11-9-12-17-23)42-24-18-13-10-14-19-24)34-27(36)25-20-15-21-35(25)29(37)26(31(3,4)5)33-30(38)40-32(6,7)8/h9-14,16-19,22,25-26,28H,15,20-21H2,1-8H3,(H,33,38)(H,34,36)/t25-,26+,28?/m0/s1
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n/an/a 9.30E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50577904
PNG
(CHEMBL4879313)
Show SMILES CC(C)C(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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n/an/a 9.30E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50524821
PNG
(CHEMBL4462682)
Show SMILES CCC(C)C(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
Show InChI InChI=1S/C33H48N3O7P/c1-9-23(2)29(44(40,42-24-17-12-10-13-18-24)43-25-19-14-11-15-20-25)35-28(37)26-21-16-22-36(26)30(38)27(32(3,4)5)34-31(39)41-33(6,7)8/h10-15,17-20,23,26-27,29H,9,16,21-22H2,1-8H3,(H,34,39)(H,35,37)/t23?,26-,27+,29?/m0/s1
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n/an/a 1.03E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50577902
PNG
(CHEMBL4855269)
Show SMILES CC(C)C(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)NC(C)(C)C)C(C)(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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n/an/a 1.07E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50524816
PNG
(CHEMBL2163507)
Show SMILES CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(C(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
Show InChI InChI=1S/C31H44N3O7P/c1-21(2)26(32-30(37)39-31(5,6)7)29(36)34-20-14-19-25(34)27(35)33-28(22(3)4)42(38,40-23-15-10-8-11-16-23)41-24-17-12-9-13-18-24/h8-13,15-18,21-22,25-26,28H,14,19-20H2,1-7H3,(H,32,37)(H,33,35)/t25-,26-,28?/m0/s1
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Article
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n/an/a 1.25E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50603189
PNG
(CHEMBL5176808)
Show SMILES CC(C)C(NC(=O)[C@@H]1C[C@H](CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)OC(=O)CN)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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n/an/a 1.39E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50577903
PNG
(CHEMBL4874616)
Show SMILES CCC(C)C(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)NC(C)(C)C)C(C)(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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n/an/a 1.41E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50603187
PNG
(CHEMBL5193418)
Show SMILES CC(C)C(NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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n/an/a 1.42E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50603190
PNG
(CHEMBL5202270)
Show SMILES CC(C)C(NC(=O)[C@@H]1C[C@H](CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)OC(=O)CCN)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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n/an/a 1.53E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50524817
PNG
(CHEMBL4583962)
Show SMILES CC(C)C(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
Show InChI InChI=1S/C32H46N3O7P/c1-22(2)28(43(39,41-23-16-11-9-12-17-23)42-24-18-13-10-14-19-24)34-27(36)25-20-15-21-35(25)29(37)26(31(3,4)5)33-30(38)40-32(6,7)8/h9-14,16-19,22,25-26,28H,15,20-21H2,1-8H3,(H,33,38)(H,34,36)/t25-,26+,28?/m0/s1
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n/an/a 1.59E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50577899
PNG
(CHEMBL4856083)
Show SMILES CCC(C)C(NC(=O)C(C)n1cccc(NC(=O)Oc2ccccc2)c1=O)P(=O)(Oc1ccccc1)Oc1ccccc1
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n/an/a 1.98E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50524816
PNG
(CHEMBL2163507)
Show SMILES CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(C(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
Show InChI InChI=1S/C31H44N3O7P/c1-21(2)26(32-30(37)39-31(5,6)7)29(36)34-20-14-19-25(34)27(35)33-28(22(3)4)42(38,40-23-15-10-8-11-16-23)41-24-17-12-9-13-18-24/h8-13,15-18,21-22,25-26,28H,14,19-20H2,1-7H3,(H,32,37)(H,33,35)/t25-,26-,28?/m0/s1
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n/an/a 2.19E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50603191
PNG
(CHEMBL5197878)
Show SMILES CC(C)C(NC(=O)[C@@H]1C[C@@H](CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)n1nnc(O)c1O)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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n/an/a 2.30E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50577905
PNG
(CHEMBL4847846)
Show SMILES CCC(C)C(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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n/an/a 2.49E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50577895
PNG
(CHEMBL4874099)
Show SMILES CC(C)C(NC(=O)Cn1cccc(NC(=O)Oc2ccccc2)c1=O)P(=O)(Oc1ccccc1)Oc1ccccc1
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n/an/a 2.90E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50603195
PNG
(CHEMBL5188060)
Show SMILES CC(C)C(NC(=O)[C@@H]1C[C@@H](CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)n1nncc1C(C)(C)O)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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n/an/a 3.03E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50577896
PNG
(CHEMBL4864962)
Show SMILES CC(C)C(NC(=O)C(C)n1cccc(NC(=O)Oc2ccccc2)c1=O)P(=O)(Oc1ccccc1)Oc1ccccc1
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n/an/a 4.18E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50577898
PNG
(CHEMBL4878469)
Show SMILES CCC(C)C(NC(=O)Cn1cccc(NC(=O)Oc2ccccc2)c1=O)P(=O)(Oc1ccccc1)Oc1ccccc1
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n/an/a 4.83E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50603183
PNG
(CHEMBL5195588)
Show SMILES CC(C)C(NC(=O)[C@@H]1C[C@H](O)CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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n/an/a 4.87E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50603184
PNG
(CHEMBL5169753)
Show SMILES CC(C)C(NC(=O)[C@@H]1C[C@H](CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)c1ccccc1)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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n/an/a 5.95E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50603192
PNG
(CHEMBL5190705)
Show SMILES CC(C)C(NC(=O)[C@@H]1C[C@H](CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)n1cc(nn1)C(C)(C)O)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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n/an/a 7.16E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50577897
PNG
(CHEMBL4877732)
Show SMILES CC(C)C(NC(=O)C(C)n1cccc(NC(=O)OC(C)(C)C)c1=O)P(=O)(Oc1ccccc1)Oc1ccccc1
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n/an/a 7.70E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50603193
PNG
(CHEMBL5179147)
Show SMILES CC(C)C(NC(=O)[C@@H]1C[C@H](CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)n1cc(CO)nn1)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.97E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50603185
PNG
(CHEMBL5202513)
Show SMILES CC(C)C(NC(=O)[C@@H]1CCCCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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UniProtKB/SwissProt

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UniChem
Article
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n/an/a 8.18E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50603194
PNG
(CHEMBL5180728)
Show SMILES CC(C)C(NC(=O)[C@@H]1C[C@H](CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)n1nncc1C(C)(C)O)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
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UniProtKB/SwissProt

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AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.57E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50577900
PNG
(CHEMBL4849209)
Show SMILES CCC(C)C(NC(=O)C(C)n1cccc(NC(=O)OC(C)(C)C)c1=O)P(=O)(Oc1ccccc1)Oc1ccccc1
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.29E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113692
BindingDB Entry DOI: 10.7270/Q25X2DR2
More data for this
Ligand-Target Pair
Probable periplasmic serine endoprotease DegP-like


(Chlamydia trachomatis (strain D/UW-3/Cx))
BDBM50603186
PNG
(CHEMBL5178486)
Show SMILES CC(C)C(NC(=O)[C@@H]1C[C@H](CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)C1CCCCC1)P(=O)(Oc1ccccc1)Oc1ccccc1 |r|
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.63E+5n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114064
BindingDB Entry DOI: 10.7270/Q29S1W48
More data for this
Ligand-Target Pair