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Compile Data Set for Download or QSAR

Found 2 hits of ec50 for UniProtKB: P40989   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
1,3-beta-glucan synthase component GSC2


(Saccharomyces cerevisiae)
BDBM50499726
PNG
(CHEMBL3742181)
Show SMILES Fc1ccc(Br)c(c1)C(=O)c1ccc(OCC(=O)Nc2cccnc2)cc1
Show InChI InChI=1S/C20H14BrFN2O3/c21-18-8-5-14(22)10-17(18)20(26)13-3-6-16(7-4-13)27-12-19(25)24-15-2-1-9-23-11-15/h1-11H,12H2,(H,24,25)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 4.60E+3n/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Induction of dissociation of [3H]-dofetilide from Kv11.1 channel (unknown origin) assessed as dissociation rate expressed in HEK293 cells after 1 hr


Eur J Med Chem 106: 50-9 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.032
BindingDB Entry DOI: 10.7270/Q25X2CZB
More data for this
Ligand-Target Pair
1,3-beta-glucan synthase component GSC2


(Saccharomyces cerevisiae)
BDBM50499725
PNG
(CHEMBL3740963)
Show SMILES Brc1ccccc1C(=O)c1ccc(OCC(=O)Nc2cccnc2)cc1
Show InChI InChI=1S/C20H15BrN2O3/c21-18-6-2-1-5-17(18)20(25)14-7-9-16(10-8-14)26-13-19(24)23-15-4-3-11-22-12-15/h1-12H,13H2,(H,23,24)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.20E+4n/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Induction of dissociation of [3H]-dofetilide from Kv11.1 channel (unknown origin) assessed as dissociation rate expressed in HEK293 cells after 1 hr


Eur J Med Chem 106: 50-9 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.032
BindingDB Entry DOI: 10.7270/Q25X2CZB
More data for this
Ligand-Target Pair