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Compile Data Set for Download or QSAR

Found 1 hit of ki for UniProtKB: P40925   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Malate dehydrogenase, cytoplasmic


(Homo sapiens (Human))		BDBM50250242
PNG
(CHEMBL4068781)
Show SMILES COC(=O)c1cccc(NC(=O)CCOc2ccc(cc2)C(C)(C)CC(C)(C)C)c1
Show InChI InChI=1S/C25H33NO4/c1-24(2,3)17-25(4,5)19-10-12-21(13-11-19)30-15-14-22(27)26-20-9-7-8-18(16-20)23(28)29-6/h7-13,16H,14-15,17H2,1-6H3,(H,26,27)
PDB
MMDB

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Similars
Article
PubMed
 740n/an/an/an/an/an/an/an/a



College of Pharmacy, Dongguk University , Goyang 10326, Korea.

Curated by ChEMBL


Assay Description
Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assay

J Med Chem 60: 8631-8646 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01231
BindingDB Entry DOI: 10.7270/Q2QZ2DCF
More data for this
Ligand-Target Pair