Compile Data Set for Download or QSAR

Found 30 hits of ic50 for UniProtKB: P55786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50277140 (CHEMBL3244800) Show SMILES CN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](NC(=O)[C@@H](N)CSC(c2ccccc2)c2ccccc2)[C@H]1O |r| Show InChI InChI=1S/C28H33N7O4S/c1-34(2)25-22-26(31-15-30-25)35(16-32-22)28-23(37)21(20(13-36)39-28)33-27(38)19(29)14-40-24(17-9-5-3-6-10-17)18-11-7-4-8-12-18/h3-12,15-16,19-21,23-24,28,36-37H,13-14,29H2,1-2H3,(H,33,38)/t19-,20+,21+,23+,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...				Eur J Med Chem 139: 325-336 (2017) Article DOI: 10.1016/j.ejmech.2017.07.048 BindingDB Entry DOI: 10.7270/Q2FT8PJD
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50277143 (CHR 2797 | CHR-2797 | Tosedostat) Show SMILES CC(C)C[C@H]([C@H](O)C(=O)NO)C(=O)N[C@H](C(=O)OC1CCCC1)c1ccccc1 |r| Show InChI InChI=1S/C21H30N2O6/c1-13(2)12-16(18(24)20(26)23-28)19(25)22-17(14-8-4-3-5-9-14)21(27)29-15-10-6-7-11-15/h3-5,8-9,13,15-18,24,28H,6-7,10-12H2,1-2H3,(H,22,25)(H,23,26)/t16-,17+,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...				Eur J Med Chem 139: 325-336 (2017) Article DOI: 10.1016/j.ejmech.2017.07.048 BindingDB Entry DOI: 10.7270/Q2FT8PJD
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50277160 (CHEMBL3244799) Show SMILES CN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](NC(=O)[C@@H](N)CSCc2ccccc2)[C@H]1O |r| Show InChI InChI=1S/C22H29N7O4S/c1-28(2)19-17-20(25-11-24-19)29(12-26-17)22-18(31)16(15(8-30)33-22)27-21(32)14(23)10-34-9-13-6-4-3-5-7-13/h3-7,11-12,14-16,18,22,30-31H,8-10,23H2,1-2H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...				Eur J Med Chem 139: 325-336 (2017) Article DOI: 10.1016/j.ejmech.2017.07.048 BindingDB Entry DOI: 10.7270/Q2FT8PJD
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50277156 (CHEMBL4165328) Show SMILES CN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](NC(=O)[C@@H](N)CSC(c2ccccc2)(c2ccccc2)c2ccccc2)[C@H]1O |r| Show InChI InChI=1S/C34H37N7O4S/c1-40(2)30-28-31(37-20-36-30)41(21-38-28)33-29(43)27(26(18-42)45-33)39-32(44)25(35)19-46-34(22-12-6-3-7-13-22,23-14-8-4-9-15-23)24-16-10-5-11-17-24/h3-17,20-21,25-27,29,33,42-43H,18-19,35H2,1-2H3,(H,39,44)/t25-,26+,27+,29+,33+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...				Eur J Med Chem 139: 325-336 (2017) Article DOI: 10.1016/j.ejmech.2017.07.048 BindingDB Entry DOI: 10.7270/Q2FT8PJD
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499710 (CHEMBL516021) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1cccnc1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C30H28N4O2/c1-2-36-30(35)28-26(33-24-13-5-3-6-14-24)19-27(22-11-9-17-31-20-22)34(25-15-7-4-8-16-25)29(28)23-12-10-18-32-21-23/h3-18,20-21,27,29,33H,2,19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50277158 (3123L | CHEBI:17939 | CL-13900 | GNF-Pf-2016 | P-6...) Show SMILES COc1ccc(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)n2cnc3c(ncnc23)N(C)C)cc1 |r| Show InChI InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50121712 (ANTAQ | CHEMBL169736) Show SMILES O=c1[nH]c2ccccc2c(=O)n1-c1c2ccccc2cc2ccccc12 |(11.65,-3.55,;10.32,-2.77,;8.96,-3.54,;7.62,-2.77,;6.29,-3.54,;4.96,-2.77,;4.96,-1.22,;6.29,-.44,;7.63,-1.22,;8.96,-.43,;8.96,1.11,;10.32,-1.22,;11.65,-.45,;12.98,-1.22,;12.98,-2.74,;14.31,-3.53,;15.64,-2.76,;15.65,-1.22,;14.32,-.47,;14.33,1.09,;12.98,1.85,;12.98,3.38,;11.65,4.15,;10.33,3.37,;10.33,1.85,;11.65,1.09,)| Show InChI InChI=1S/C22H14N2O2/c25-21-18-11-5-6-12-19(18)23-22(26)24(21)20-16-9-3-1-7-14(16)13-15-8-2-4-10-17(15)20/h1-13H,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Puromycin sensitive aminopeptidase inhibitory activity of the compound was determined by the use of L-Ala AMC with MOLT-4				Bioorg Med Chem Lett 13: 83-6 (2002) BindingDB Entry DOI: 10.7270/Q2RV0N1C
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50121708 (CHEMBL168510 | MPAQ-22) Show SMILES CCc1cccc(CC)c1-n1c(=O)n(C)c2ccccc2c1=O |(13.4,-3.31,;12.07,-2.53,;12.09,-.99,;13.42,-.23,;13.42,1.32,;12.09,2.09,;10.76,1.32,;9.41,2.09,;9.41,3.63,;10.76,-.22,;9.41,-.98,;9.41,-2.53,;10.74,-3.31,;8.06,-3.3,;8.06,-4.84,;6.73,-2.53,;5.4,-3.3,;4.07,-2.53,;4.07,-.98,;5.4,-.21,;6.73,-.98,;8.07,-.19,;8.07,1.35,)| Show InChI InChI=1S/C19H20N2O2/c1-4-13-9-8-10-14(5-2)17(13)21-18(22)15-11-6-7-12-16(15)20(3)19(21)23/h6-12H,4-5H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Puromycin sensitive aminopeptidase inhibitory activity of the compound was determined by the use of L-Ala AMC with MOLT-4				Bioorg Med Chem Lett 13: 83-6 (2002) BindingDB Entry DOI: 10.7270/Q2RV0N1C
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...				Eur J Med Chem 139: 325-336 (2017) Article DOI: 10.1016/j.ejmech.2017.07.048 BindingDB Entry DOI: 10.7270/Q2FT8PJD
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50121709 (CHEMBL169458 | PAQ-22) Show SMILES CCc1cccc(CC)c1-n1c(=O)[nH]c2ccccc2c1=O |(9.41,3.63,;9.41,2.09,;10.76,1.32,;12.09,2.09,;13.42,1.32,;13.42,-.23,;12.09,-.99,;12.07,-2.53,;13.4,-3.31,;10.76,-.22,;9.41,-.98,;9.41,-2.53,;10.74,-3.31,;8.06,-3.3,;6.73,-2.53,;5.4,-3.3,;4.07,-2.53,;4.07,-.98,;5.4,-.21,;6.73,-.98,;8.07,-.19,;8.07,1.35,)| Show InChI InChI=1S/C18H18N2O2/c1-3-12-8-7-9-13(4-2)16(12)20-17(21)14-10-5-6-11-15(14)19-18(20)22/h5-11H,3-4H2,1-2H3,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Puromycin sensitive aminopeptidase inhibitory activity of the compound was determined by the use of L-Ala AMC with MOLT-4				Bioorg Med Chem Lett 13: 83-6 (2002) BindingDB Entry DOI: 10.7270/Q2RV0N1C
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50121711 (CHEMBL169895 | DAMPAQ) Show SMILES CCc1cc(NS(=O)(=O)c2ccc3c(cccc3c2)N(C)C)cc(CC)c1-n1c(=O)n(C)c2ccccc2c1=O |(6.43,-1.61,;6.43,-3.15,;7.78,-3.92,;9.1,-3.15,;10.44,-3.92,;11.76,-3.15,;11.76,-1.61,;13.3,-1.61,;10.23,-1.64,;11.76,-.08,;10.43,.68,;10.41,2.23,;11.74,3,;11.74,4.55,;13.07,5.35,;14.43,4.58,;14.44,3.02,;13.09,2.23,;13.11,.7,;10.41,5.31,;10.39,6.84,;9.08,4.53,;10.43,-5.47,;9.1,-6.22,;9.09,-7.76,;10.41,-8.54,;7.78,-5.46,;6.43,-6.22,;6.43,-7.76,;7.76,-8.54,;5.08,-8.53,;5.08,-10.06,;3.76,-7.76,;2.43,-8.53,;1.1,-7.76,;1.1,-6.22,;2.43,-5.45,;3.76,-6.22,;5.1,-5.43,;5.1,-3.9,)| Show InChI InChI=1S/C31H32N4O4S/c1-6-20-17-23(32-40(38,39)24-15-16-25-22(19-24)11-10-14-27(25)33(3)4)18-21(7-2)29(20)35-30(36)26-12-8-9-13-28(26)34(5)31(35)37/h8-19,32H,6-7H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Puromycin sensitive aminopeptidase inhibitory activity of the compound was determined by the use of L-Ala AMC with MOLT-4				Bioorg Med Chem Lett 13: 83-6 (2002) BindingDB Entry DOI: 10.7270/Q2RV0N1C
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50277142 (CHEMBL4161892) Show SMILES CN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](NC(=O)[C@H](N)CSC(c2ccccc2)c2ccccc2)[C@H]1O |r| Show InChI InChI=1S/C28H33N7O4S/c1-34(2)25-22-26(31-15-30-25)35(16-32-22)28-23(37)21(20(13-36)39-28)33-27(38)19(29)14-40-24(17-9-5-3-6-10-17)18-11-7-4-8-12-18/h3-12,15-16,19-21,23-24,28,36-37H,13-14,29H2,1-2H3,(H,33,38)/t19-,20-,21-,23-,28-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...				Eur J Med Chem 139: 325-336 (2017) Article DOI: 10.1016/j.ejmech.2017.07.048 BindingDB Entry DOI: 10.7270/Q2FT8PJD
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50277141 (CHEMBL4161496) Show SMILES CN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](NC(=O)[C@@H](N)Cc2ccccc2)[C@H]1O |r| Show InChI InChI=1S/C21H27N7O4/c1-27(2)18-16-19(24-10-23-18)28(11-25-16)21-17(30)15(14(9-29)32-21)26-20(31)13(22)8-12-6-4-3-5-7-12/h3-7,10-11,13-15,17,21,29-30H,8-9,22H2,1-2H3,(H,26,31)/t13-,14+,15+,17+,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...				Eur J Med Chem 139: 325-336 (2017) Article DOI: 10.1016/j.ejmech.2017.07.048 BindingDB Entry DOI: 10.7270/Q2FT8PJD
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50121710 (2-(2,6-Diethyl-phenyl)-4H-isoquinoline-1,3-dione |...) Show SMILES CCc1cccc(CC)c1-n1c(O)cc2ccccc2c1=O |(6.7,5.02,;6.72,3.48,;8.06,2.72,;9.38,3.49,;10.73,2.73,;10.73,1.19,;9.4,.41,;9.4,-1.13,;10.74,-1.9,;8.07,1.18,;6.74,.41,;6.74,-1.13,;8.08,-1.9,;5.41,-1.9,;4.07,-1.15,;2.74,-1.92,;1.41,-1.15,;1.41,.39,;2.74,1.17,;4.07,.4,;5.4,1.18,;5.4,2.72,)| Show InChI InChI=1S/C19H19NO2/c1-3-13-9-7-10-14(4-2)18(13)20-17(21)12-15-8-5-6-11-16(15)19(20)22/h5-12,21H,3-4H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Puromycin sensitive aminopeptidase inhibitory activity of the compound was determined by the use of L-Ala AMC with MOLT-4				Bioorg Med Chem Lett 13: 83-6 (2002) BindingDB Entry DOI: 10.7270/Q2RV0N1C
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499702 (CHEMBL3740370) Show SMILES CCOC(=O)C1C(N(C(CC1=O)c1cccnc1)c1ccccc1)c1cccnc1 Show InChI InChI=1S/C24H23N3O3/c1-2-30-24(29)22-21(28)14-20(17-8-6-12-25-15-17)27(19-10-4-3-5-11-19)23(22)18-9-7-13-26-16-18/h3-13,15-16,20,22-23H,2,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499709 (CHEMBL3741560) Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccc(C)cc1)c1ccccc1)Nc1ccc(C)cc1 |t:5| Show InChI InChI=1S/C33H33N3O2/c1-4-38-33(37)31-29(35-26-17-13-23(2)14-18-26)22-30(25-10-6-5-7-11-25)36(27-19-15-24(3)16-20-27)32(31)28-12-8-9-21-34-28/h5-21,30,32,35H,4,22H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50277158 (3123L | CHEBI:17939 | CL-13900 | GNF-Pf-2016 | P-6...) Show SMILES COc1ccc(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)n2cnc3c(ncnc23)N(C)C)cc1 |r| Show InChI InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...				Eur J Med Chem 139: 325-336 (2017) Article DOI: 10.1016/j.ejmech.2017.07.048 BindingDB Entry DOI: 10.7270/Q2FT8PJD
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499705 (CHEMBL3741724) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1ccc(cc1)C#N)Nc1ccccc1 |t:5| Show InChI InChI=1S/C32H28N4O2/c1-2-38-32(37)30-28(35-26-11-5-3-6-12-26)20-29(24-17-15-23(21-33)16-18-24)36(27-13-7-4-8-14-27)31(30)25-10-9-19-34-22-25/h3-19,22,29,31,35H,2,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499712 (CHEMBL3741833) Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccccc1)c1ccc(cc1)C#N)Nc1ccccc1 |t:5| Show InChI InChI=1S/C32H28N4O2/c1-2-38-32(37)30-28(35-25-11-5-3-6-12-25)21-29(24-18-16-23(22-33)17-19-24)36(26-13-7-4-8-14-26)31(30)27-15-9-10-20-34-27/h3-20,29,31,35H,2,21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499707 (CHEMBL3741904) Show SMILES OC1=CC(N(C(C1)c1cccnc1)c1ccccc1)c1cccnc1 |t:1| Show InChI InChI=1S/C21H19N3O/c25-19-12-20(16-6-4-10-22-14-16)24(18-8-2-1-3-9-18)21(13-19)17-7-5-11-23-15-17/h1-12,14-15,20-21,25H,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499708 (CHEMBL3739649) Show SMILES OC1=CC(N(C(C1)c1ccccn1)c1ccccc1)c1ccccn1 |t:1| Show InChI InChI=1S/C21H19N3O/c25-17-14-20(18-10-4-6-12-22-18)24(16-8-2-1-3-9-16)21(15-17)19-11-5-7-13-23-19/h1-14,20-21,25H,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499706 (CHEMBL3740199) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1cc(OC)c(OC)c(OC)c1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C34H35N3O5/c1-5-42-34(38)31-27(36-25-14-8-6-9-15-25)21-28(24-19-29(39-2)33(41-4)30(20-24)40-3)37(26-16-10-7-11-17-26)32(31)23-13-12-18-35-22-23/h6-20,22,28,32,36H,5,21H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50277157 (CHEMBL4173240) Show SMILES CN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](NC(=O)[C@H](N)CSCc2ccccc2)[C@H]1O |r| Show InChI InChI=1S/C22H29N7O4S/c1-28(2)19-17-20(25-11-24-19)29(12-26-17)22-18(31)16(15(8-30)33-22)27-21(32)14(23)10-34-9-13-6-4-3-5-7-13/h3-7,11-12,14-16,18,22,30-31H,8-10,23H2,1-2H3,(H,27,32)/t14-,15-,16-,18-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...				Eur J Med Chem 139: 325-336 (2017) Article DOI: 10.1016/j.ejmech.2017.07.048 BindingDB Entry DOI: 10.7270/Q2FT8PJD
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50277150 (CHEMBL4161744) Show SMILES N[C@@H](CSC(c1ccccc1)c1ccccc1)C(=O)NCCCO |r| Show InChI InChI=1S/C19H24N2O2S/c20-17(19(23)21-12-7-13-22)14-24-18(15-8-3-1-4-9-15)16-10-5-2-6-11-16/h1-6,8-11,17-18,22H,7,12-14,20H2,(H,21,23)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...				Eur J Med Chem 139: 325-336 (2017) Article DOI: 10.1016/j.ejmech.2017.07.048 BindingDB Entry DOI: 10.7270/Q2FT8PJD
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499704 (CHEMBL3740158) Show SMILES COC(=O)C1=C(CC(N(C1c1ccc(cc1)[N+]([O-])=O)c1ccccc1)c1ccc(cc1)[N+]([O-])=O)Nc1ccccc1 |t:4| Show InChI InChI=1S/C31H26N4O6/c1-41-31(36)29-27(32-23-8-4-2-5-9-23)20-28(21-12-16-25(17-13-21)34(37)38)33(24-10-6-3-7-11-24)30(29)22-14-18-26(19-15-22)35(39)40/h2-19,28,30,32H,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499713 (CHEMBL3741344) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccs1)c1ccccc1)c1ccc(Br)cc1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C30H27BrN2O2S/c1-2-35-30(34)28-25(32-23-10-5-3-6-11-23)20-26(21-15-17-22(31)18-16-21)33(24-12-7-4-8-13-24)29(28)27-14-9-19-36-27/h3-19,26,29,32H,2,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499701 (CHEMBL3741701) Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccccc1)c1ccccn1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C30H28N4O2/c1-2-36-30(35)28-26(33-22-13-5-3-6-14-22)21-27(24-17-9-11-19-31-24)34(23-15-7-4-8-16-23)29(28)25-18-10-12-20-32-25/h3-20,27,29,33H,2,21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499703 (CHEMBL3740862) Show SMILES CCOC(=O)C1C(N(C(CC1=O)c1ccccn1)c1ccccc1)c1ccccn1 Show InChI InChI=1S/C24H23N3O3/c1-2-30-24(29)22-21(28)16-20(18-12-6-8-14-25-18)27(17-10-4-3-5-11-17)23(22)19-13-7-9-15-26-19/h3-15,20,22-23H,2,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499711 (CHEMBL3741419) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1ccc(Cl)cc1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C31H28ClN3O2/c1-2-37-31(36)29-27(34-25-11-5-3-6-12-25)20-28(22-15-17-24(32)18-16-22)35(26-13-7-4-8-14-26)30(29)23-10-9-19-33-21-23/h3-19,21,28,30,34H,2,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50277159 (CHEMBL4169814) Show SMILES CN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](NC(=O)[C@H](N)CSC(c2ccccc2)(c2ccccc2)c2ccccc2)[C@H]1O |r| Show InChI InChI=1S/C34H37N7O4S/c1-40(2)30-28-31(37-20-36-30)41(21-38-28)33-29(43)27(26(18-42)45-33)39-32(44)25(35)19-46-34(22-12-6-3-7-13-22,23-14-8-4-9-15-23)24-16-10-5-11-17-24/h3-17,20-21,25-27,29,33,42-43H,18-19,35H2,1-2H3,(H,39,44)/t25-,26-,27-,29-,33-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...				Eur J Med Chem 139: 325-336 (2017) Article DOI: 10.1016/j.ejmech.2017.07.048 BindingDB Entry DOI: 10.7270/Q2FT8PJD
					More data for this Ligand-Target Pair