BindingDB PrimarySearch

Found 9 hits of ic50 for UniProtKB: P19835
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Bile salt-activated lipase (Homo sapiens (Human))	BDBM50244756 (2-(2,3,5,6-Tetrafluoropyridin-4-yl)-1,2-benzisothi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leipzig Curated by ChEMBL					Assay Description Inhibition of cholesterol esterase (unknown origin)				Bioorg Med Chem 16: 8127-35 (2008) Article DOI: 10.1016/j.bmc.2008.07.049 BindingDB Entry DOI: 10.7270/Q26M36NT
University of Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt-activated lipase (Homo sapiens (Human))	BDBM50244755 (2-(Pyridin-4-yl)-4,5,6,7-tetrahydro-1,2-benzisothi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Leipzig Curated by ChEMBL					Assay Description Inhibition of cholesterol esterase (unknown origin)				Bioorg Med Chem 16: 8127-35 (2008) Article DOI: 10.1016/j.bmc.2008.07.049 BindingDB Entry DOI: 10.7270/Q26M36NT
University of Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt-activated lipase (Homo sapiens (Human))	BDBM50244754 (2-(2,3,4,5,6-Pentafluorophenyl)-4,5,6,7-tetrahydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Leipzig Curated by ChEMBL					Assay Description Inhibition of cholesterol esterase (unknown origin)				Bioorg Med Chem 16: 8127-35 (2008) Article DOI: 10.1016/j.bmc.2008.07.049 BindingDB Entry DOI: 10.7270/Q26M36NT
University of Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt-activated lipase (Homo sapiens (Human))	BDBM50244704 (2-(6-Bromopyridin-2-yl)-4,5,6,7-tetrahydro-1,2-ben...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Leipzig Curated by ChEMBL					Assay Description Inhibition of cholesterol esterase (unknown origin)				Bioorg Med Chem 16: 8127-35 (2008) Article DOI: 10.1016/j.bmc.2008.07.049 BindingDB Entry DOI: 10.7270/Q26M36NT
University of Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt-activated lipase (Homo sapiens (Human))	BDBM50244752 (4,5-Dimethyl-2-(2,3,5,6-tetrafluoropyridin-4-yl)-i...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Leipzig Curated by ChEMBL					Assay Description Inhibition of cholesterol esterase (unknown origin)				Bioorg Med Chem 16: 8127-35 (2008) Article DOI: 10.1016/j.bmc.2008.07.049 BindingDB Entry DOI: 10.7270/Q26M36NT
University of Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt-activated lipase (Homo sapiens (Human))	BDBM50244751 (2-(2,3,5,6-Tetrafluoropyridin-4-yl)-4,5,6,7-tetrah...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Leipzig Curated by ChEMBL					Assay Description Inhibition of cholesterol esterase (unknown origin)				Bioorg Med Chem 16: 8127-35 (2008) Article DOI: 10.1016/j.bmc.2008.07.049 BindingDB Entry DOI: 10.7270/Q26M36NT
University of Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt-activated lipase (Homo sapiens (Human))	BDBM50244705 (2-(3,5-Difluoropyridin-2-yl)-4,5,6,7-tetrahydro-1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Leipzig Curated by ChEMBL					Assay Description Inhibition of cholesterol esterase (unknown origin)				Bioorg Med Chem 16: 8127-35 (2008) Article DOI: 10.1016/j.bmc.2008.07.049 BindingDB Entry DOI: 10.7270/Q26M36NT
University of Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt-activated lipase (Homo sapiens (Human))	BDBM50244703 (2-(6-Chloropyridin-2-yl)-4,5,6,7-tetrahydro-1,2-be...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Leipzig Curated by ChEMBL					Assay Description Inhibition of cholesterol esterase (unknown origin)				Bioorg Med Chem 16: 8127-35 (2008) Article DOI: 10.1016/j.bmc.2008.07.049 BindingDB Entry DOI: 10.7270/Q26M36NT
University of Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt-activated lipase (Homo sapiens (Human))	BDBM50244753 (5-Methyl-4-phenyl-2-(2,3,5,6-tetrafluoropyridin-4-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Leipzig Curated by ChEMBL					Assay Description Inhibition of cholesterol esterase (unknown origin)				Bioorg Med Chem 16: 8127-35 (2008) Article DOI: 10.1016/j.bmc.2008.07.049 BindingDB Entry DOI: 10.7270/Q26M36NT
University of Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair