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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for UniProtKB: P28476   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gamma-aminobutyric acid receptor subunit rho-2


(Homo sapiens (Human))
BDBM50211642
PNG
(CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...)
Show SMILES CP(O)(=O)C1=CCNCC1 |t:4|
Show InChI InChI=1S/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9)
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CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

Patents

Article
PubMed
n/an/a 2.21E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant GABAc rho-2 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...


ACS Med Chem Lett 2: 11-16 (2011)


Article DOI: 10.1021/ml1001344
BindingDB Entry DOI: 10.7270/Q2FX79QR
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit rho-2


(Homo sapiens (Human))
BDBM50336850
PNG
(3-(guanido)-1-oxo-1-hydroxy-phospholane | CHEMBL16...)
Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-1-[#6]-[#6]P([#8])([#8])=[#6]1
Show InChI InChI=1S/C5H12N3O2P/c6-5(7)8-4-1-2-11(9,10)3-4/h3-4,9-10H,1-2H2,(H4,6,7,8)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.13E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant GABAc rho-2 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...


ACS Med Chem Lett 2: 11-16 (2011)


Article DOI: 10.1021/ml1001344
BindingDB Entry DOI: 10.7270/Q2FX79QR
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit rho-2


(Homo sapiens (Human))
BDBM50336851
PNG
(3-(aminomethyl)-1-oxo-1-hydroxy-phospholane | CHEM...)
Show SMILES NCC1CCP(O)(O)=C1
Show InChI InChI=1S/C5H12NO2P/c6-3-5-1-2-9(7,8)4-5/h4-5,7-8H,1-3,6H2
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UniProtKB/SwissProt

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antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.71E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant GABAc rho-2 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...


ACS Med Chem Lett 2: 11-16 (2011)


Article DOI: 10.1021/ml1001344
BindingDB Entry DOI: 10.7270/Q2FX79QR
More data for this
Ligand-Target Pair