Compile Data Set for Download or QSAR

Found 3 hits of ic50 for UniProtKB: P23492   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Mus musculus)	BDBM50042363 (CHEMBL333946 | {2-[2-(2-Amino-6-oxo-1,6-dihydro-pu...) Show SMILES Nc1nc2n(Cc3ccccc3CCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H16N5O4P/c15-14-17-12-11(13(20)18-14)16-8-19(12)7-10-4-2-1-3-9(10)5-6-24(21,22)23/h1-4,8H,5-7H2,(H2,21,22,23)(H3,15,17,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
BioCryst Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4				J Med Chem 36: 3771-83 (1994) BindingDB Entry DOI: 10.7270/Q23J3DKS
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Mus musculus)	BDBM50042802 (2-Amino-7-(1-cyclohexyl-3-hydroxy-propyl)-3,5-dihy...) Show SMILES Nc1nc2c(c[nH]c2c(=O)[nH]1)C(CCO)C1CCCCC1 Show InChI InChI=1S/C15H22N4O2/c16-15-18-12-11(8-17-13(12)14(21)19-15)10(6-7-20)9-4-2-1-3-5-9/h8-10,17,20H,1-7H2,(H3,16,18,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
BioCryst Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4 determined by measuring 3H release from [3H]-inosine				J Med Chem 36: 3771-83 (1994) BindingDB Entry DOI: 10.7270/Q23J3DKS
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Mus musculus)	BDBM50042802 (2-Amino-7-(1-cyclohexyl-3-hydroxy-propyl)-3,5-dihy...) Show SMILES Nc1nc2c(c[nH]c2c(=O)[nH]1)C(CCO)C1CCCCC1 Show InChI InChI=1S/C15H22N4O2/c16-15-18-12-11(8-17-13(12)14(21)19-15)10(6-7-20)9-4-2-1-3-5-9/h8-10,17,20H,1-7H2,(H3,16,18,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioCryst Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4 determined by measuring 3H release from [3H]-inosine				J Med Chem 36: 3771-83 (1994) BindingDB Entry DOI: 10.7270/Q23J3DKS
					More data for this Ligand-Target Pair