Compile Data Set for Download or QSAR

Found 7 hits of ic50 for UniProtKB: P63319   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C gamma type (Rattus norvegicus)	BDBM50282632 (3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10a-hexahydro-1...) Show SMILES CN1C[C@@H]2Cc3c(C4=C(C(=O)NC4=O)c4cn(C)c5ccccc45)c4ccccc4n3C[C@H]2C1 |r,t:7| Show InChI InChI=1S/C28H26N4O2/c1-30-12-16-11-23-24(19-8-4-6-10-22(19)32(23)14-17(16)13-30)26-25(27(33)29-28(26)34)20-15-31(2)21-9-5-3-7-18(20)21/h3-10,15-17H,11-14H2,1-2H3,(H,29,33,34)/t16-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C gamma (PKC)				Bioorg Med Chem Lett 4: 1303-1308 (1994) Article DOI: 10.1016/S0960-894X(01)80349-8 BindingDB Entry DOI: 10.7270/Q27H1JJ4
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Rattus norvegicus)	BDBM50282633 ((S)-3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydr...) Show SMILES CN(C)C[C@H]1CCn2c(C1)c(C1=C(C(=O)NC1=O)c1cn(C)c3ccccc13)c1ccccc21 |t:12| Show InChI InChI=1S/C28H28N4O2/c1-30(2)15-17-12-13-32-22-11-7-5-9-19(22)24(23(32)14-17)26-25(27(33)29-28(26)34)20-16-31(3)21-10-6-4-8-18(20)21/h4-11,16-17H,12-15H2,1-3H3,(H,29,33,34)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	36.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C gamma (PKC)				Bioorg Med Chem Lett 4: 1303-1308 (1994) Article DOI: 10.1016/S0960-894X(01)80349-8 BindingDB Entry DOI: 10.7270/Q27H1JJ4
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Rattus norvegicus)	BDBM50213062 (CHEMBL342866) Show SMILES [H][C@@]1(C)Cc2ccc3[nH]cc4C[C@@H](CO)NC(=O)[C@H](C(C)C)N1c2c34 Show InChI InChI=1S/C19H25N3O2/c1-10(2)17-19(24)21-14(9-23)7-13-8-20-15-5-4-12-6-11(3)22(17)18(12)16(13)15/h4-5,8,10-11,14,17,20,23H,6-7,9H2,1-3H3,(H,21,24)/t11-,14+,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]phorbol-12,13-dibutyrate (PDBu) binding to rat brain protein kinase C gamma regulatory domain				Citation and Details BindingDB Entry DOI: 10.7270/Q2GM89G6
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Rattus norvegicus)	BDBM50057511 ((+/-)-indolactum-V 13-Hydroxymethyl-10-isopropyl-9...) Show SMILES CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=O)c23 Show InChI InChI=1S/C17H23N3O2/c1-10(2)16-17(22)19-12(9-21)7-11-8-18-13-5-4-6-14(15(11)13)20(16)3/h4-6,8,10,12,16,18,21H,7,9H2,1-3H3,(H,19,22)/t12-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]phorbol-12,13-dibutyrate (PDBu) binding to rat brain protein kinase C gamma regulatory domain				Citation and Details BindingDB Entry DOI: 10.7270/Q2GM89G6
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Rattus norvegicus)	BDBM50213063 (CHEMBL342131) Show SMILES CC(C)[C@H]1C(=O)N[C@H](CO)Cc2c[nH]c3ccc4cc(C)n1c4c23 Show InChI InChI=1S/C19H23N3O2/c1-10(2)17-19(24)21-14(9-23)7-13-8-20-15-5-4-12-6-11(3)22(17)18(12)16(13)15/h4-6,8,10,14,17,20,23H,7,9H2,1-3H3,(H,21,24)/t14-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]phorbol-12,13-dibutyrate (PDBu) binding to rat brain protein kinase C gamma regulatory domain				Citation and Details BindingDB Entry DOI: 10.7270/Q2GM89G6
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Rattus norvegicus)	BDBM50213064 (CHEMBL342147) Show SMILES [H][C@]1(C)Cc2ccc3[nH]cc4C[C@@H](CO)NC(=O)[C@H](C(C)C)N1c2c34 Show InChI InChI=1S/C19H25N3O2/c1-10(2)17-19(24)21-14(9-23)7-13-8-20-15-5-4-12-6-11(3)22(17)18(12)16(13)15/h4-5,8,10-11,14,17,20,23H,6-7,9H2,1-3H3,(H,21,24)/t11-,14-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]phorbol-12,13-dibutyrate (PDBu) binding to rat brain protein kinase C gamma regulatory domain				Citation and Details BindingDB Entry DOI: 10.7270/Q2GM89G6
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Rattus norvegicus)	BDBM50213040 (CHEMBL141695) Show SMILES CC(C)[C@@H]1N(C)c2c(C)ccc3[nH]cc(C[C@@H](CO)NC1=O)c23 Show InChI InChI=1S/C18H25N3O2/c1-10(2)16-18(23)20-13(9-22)7-12-8-19-14-6-5-11(3)17(15(12)14)21(16)4/h5-6,8,10,13,16,19,22H,7,9H2,1-4H3,(H,20,23)/t13-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]phorbol-12,13-dibutyrate (PDBu) binding to rat brain protein kinase C gamma regulatory domain				Citation and Details BindingDB Entry DOI: 10.7270/Q2GM89G6
					More data for this Ligand-Target Pair