Compile Data Set for Download or QSAR

Found 3 hits of ic50 for UniProtKB: P67775   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50097634 (CHEMBL158524 | OKADAIC ACID | okadaic acid analogu...) Show SMILES [H][C@@]12CC[C@@]3(CC[C@@H](O3)\C=C\[C@@H](C)[C@@H]3CC(C)=C[C@@]4(O[C@H](C[C@@](C)(O)C(O)=O)CC[C@H]4O)O3)O[C@@]1([H])[C@H](O)C(=C)[C@H](O2)[C@@H](O)C[C@H](C)[C@@]1([H])O[C@@]2(CCCCO2)CC[C@H]1C |r,c:17| Show InChI InChI=1S/C44H68O13/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49)/b10-9+/t26-,27-,28+,30+,31+,32+,33-,34+,35?,36-,37+,38+,39-,41-,42+,43-,44-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against Protein phosphatase 2A (25 nM) isolated from bovine myocardial tissue				Bioorg Med Chem Lett 11: 647-9 (2001) BindingDB Entry DOI: 10.7270/Q2N29W62
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50097633 (CHEMBL2368224 | okadaic acid analogue) Show SMILES [H][C@@]1(CC[C@@]2(CC[C@@]3([H])O[C@]([H])(CO)C(=C)[C@@H](O)[C@]3([H])O2)O1)\C=C\[C@@H](C)[C@]1([H])CC(C)=C[C@@]2(O[C@]([H])(C[C@@](C)(O)C(O)=O)CC[C@H]2O)O1 |c:33| Show InChI InChI=1S/C31H46O11/c1-17-13-23(41-31(14-17)25(33)8-7-21(40-31)15-29(4,37)28(35)36)18(2)5-6-20-9-11-30(39-20)12-10-22-27(42-30)26(34)19(3)24(16-32)38-22/h5-6,14,18,20-27,32-34,37H,3,7-13,15-16H2,1-2,4H3,(H,35,36)/b6-5+/t18-,20+,21+,22-,23+,24-,25?,26-,27-,29-,30-,31-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	304	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against Protein phosphatase 2A (25 nM) isolated from bovine myocardial tissue				Bioorg Med Chem Lett 11: 647-9 (2001) BindingDB Entry DOI: 10.7270/Q2N29W62
					More data for this Ligand-Target Pair
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50097635 (CHEMBL158922 | okadaic acid analogue) Show SMILES C[C@@H](C[C@H](O)[C@H]1O[C@@H]2CC[C@@]3(CCCO3)O[C@H]2[C@H](O)C1=C)[C@H]1O[C@@]2(CCCCO2)CC[C@H]1C Show InChI InChI=1S/C26H42O7/c1-16-7-11-25(9-4-5-13-29-25)32-22(16)17(2)15-19(27)23-18(3)21(28)24-20(31-23)8-12-26(33-24)10-6-14-30-26/h16-17,19-24,27-28H,3-15H2,1-2H3/t16-,17+,19+,20-,21-,22+,23+,24-,25+,26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against Protein phosphatase 2A (25 nM) isolated from bovine myocardial tissue				Bioorg Med Chem Lett 11: 647-9 (2001) BindingDB Entry DOI: 10.7270/Q2N29W62
					More data for this Ligand-Target Pair