Found 5 hits of ki for UniProtKB: P50554 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
4-aminobutyrate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50137629
(4-Amino-4,5-dihydro-furan-2-carboxylic acid anion)Show InChI InChI=1S/C5H7NO3/c6-3-1-4(5(7)8)9-2-3/h1,3H,2,6H2,(H,7,8)/p-1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| PubMed
| 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description
KI for pyridoxal 5'-phosphate (PLP)-dependent Gamma-amino-N-butyrate transaminase at pH 7.4 |
Bioorg Med Chem Lett 14: 203-6 (2003)
BindingDB Entry DOI: 10.7270/Q28916DF |
More data for this
Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50255245
(3-chloro-1-(4-hydroxyphenyl)propan-1-one | CHEMBL5...)Show InChI InChI=1S/C9H9ClO2/c10-6-5-9(12)7-1-3-8(11)4-2-7/h1-4,11H,5-6H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description
Activity of GABA transaminase in rat brain |
Bioorg Med Chem Lett 19: 731-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.033
BindingDB Entry DOI: 10.7270/Q2T72H9G |
More data for this
Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50401019
(CHEMBL2203661)Show SMILES [#7+]-[#6@H]1-[#6@H](-[#6]-[#6]\[#6]-1=[#6](/F)F)-[#6](-[#8-])=O |r| Show InChI InChI=1S/C7H9F2NO2/c8-6(9)3-1-2-4(5(3)10)7(11)12/h4-5H,1-2,10H2,(H,11,12)/t4-,5+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description
Inactivation of GABA-AT in rat brain homogenate |
J Med Chem 55: 357-66 (2012)
Article DOI: 10.1021/jm201231w
BindingDB Entry DOI: 10.7270/Q2QF8V1F |
More data for this
Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50118886
(4-Amino-hex-5-enoic acid | CHEMBL89598 | US1018980...)Show InChI InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description
Inactivation of GABA-AT in rat brain homogenate |
J Med Chem 55: 357-66 (2012)
Article DOI: 10.1021/jm201231w
BindingDB Entry DOI: 10.7270/Q2QF8V1F |
More data for this
Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50118886
(4-Amino-hex-5-enoic acid | CHEMBL89598 | US1018980...)Show InChI InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description
Inhibition of rat GABA aminotransferase by modified Scott and Jacoby method |
Bioorg Med Chem 20: 5763-73 (2012)
Article DOI: 10.1016/j.bmc.2012.08.009
BindingDB Entry DOI: 10.7270/Q26H4JHH |
More data for this
Ligand-Target Pair | |
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