Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chitin synthase 1 (Candida albicans) | BDBM50559071 (CHEMBL4741395) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Candida albicans chitin synthase 1 expressed in Saccharomyces cerevisiae RRA400-1U cells using [3H]UDP-GlcNAc as substrate by scintilla... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00748 BindingDB Entry DOI: 10.7270/Q2348Q30 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitin synthase 1 (Candida albicans) | BDBM50367322 (CHEMBL1791178) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrations | J Med Chem 29: 802-9 (1986) BindingDB Entry DOI: 10.7270/Q2N01734 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitin synthase 1 (Candida albicans) | BDBM50559072 (CHEMBL4786444) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Candida albicans chitin synthase 1 expressed in Saccharomyces cerevisiae RRA400-1U cells using [3H]UDP-GlcNAc as substrate by scintilla... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00748 BindingDB Entry DOI: 10.7270/Q2348Q30 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitin synthase 1 (Candida albicans) | BDBM50367323 (CHEMBL1791436) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 7.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for the inhibitory activity against chitin synthetase | J Med Chem 29: 802-9 (1986) BindingDB Entry DOI: 10.7270/Q2N01734 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitin synthase 1 (Candida albicans) | BDBM50367324 (CHEMBL1791438) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for the inhibitory activity against chitin synthetase | J Med Chem 29: 802-9 (1986) BindingDB Entry DOI: 10.7270/Q2N01734 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitin synthase 1 (Candida albicans) | BDBM50367327 (CHEMBL1791441) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.45E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for the inhibitory activity against chitin synthetase | J Med Chem 29: 802-9 (1986) BindingDB Entry DOI: 10.7270/Q2N01734 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitin synthase 1 (Candida albicans) | BDBM50367325 (CHEMBL1791435) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.18E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrations | J Med Chem 29: 802-9 (1986) BindingDB Entry DOI: 10.7270/Q2N01734 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitin synthase 1 (Candida albicans) | BDBM50367326 (CHEMBL1791440) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.46E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrations | J Med Chem 29: 802-9 (1986) BindingDB Entry DOI: 10.7270/Q2N01734 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitin synthase 1 (Candida albicans) | BDBM50367320 (CHEMBL1791437) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.78E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrations | J Med Chem 29: 802-9 (1986) BindingDB Entry DOI: 10.7270/Q2N01734 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitin synthase 1 (Candida albicans) | BDBM50367321 (CHEMBL1791439) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.06E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrations | J Med Chem 29: 802-9 (1986) BindingDB Entry DOI: 10.7270/Q2N01734 | |||||||||||
More data for this Ligand-Target Pair |