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Compile Data Set for Download or QSAR

Found 2 hits of kd for UniProtKB: Q9P0X4   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1I


(Homo sapiens (Human))
BDBM50017702
PNG
(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)
Show SMILES Fc1ccc(cc1)C(N1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1
Show InChI InChI=1S/C26H26F2N2/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21/h1-15,26H,16-20H2/b7-4+
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n/an/an/a 840n/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Binding affinity to T-type alpha1I calcium channel


Bioorg Med Chem Lett 21: 215-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.11.033
BindingDB Entry DOI: 10.7270/Q2765FKR
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1I


(Homo sapiens (Human))
BDBM50017702
PNG
(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)
Show SMILES Fc1ccc(cc1)C(N1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1
Show InChI InChI=1S/C26H26F2N2/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21/h1-15,26H,16-20H2/b7-4+
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MCE
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PC sid
UniChem

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DrugBank
Article
PubMed
n/an/an/a 840n/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Inhibition of T-type Cav3.3 channel


Bioorg Med Chem 18: 5938-44 (2010)


Article DOI: 10.1016/j.bmc.2010.06.082
BindingDB Entry DOI: 10.7270/Q2ZS2WQ5
More data for this
Ligand-Target Pair