Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CX3C chemokine receptor 1 (Homo sapiens (Human)) | BDBM50559936 (CHEMBL4744046) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human CX3CR1 expressed in CHO-K1 cells by PathHunter beta-arrestin assay | Citation and Details Article DOI: 10.1016/j.bmc.2020.115546 BindingDB Entry DOI: 10.7270/Q2F193D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CX3C chemokine receptor 1 (Homo sapiens (Human)) | BDBM50255479 (CHEMBL4067429) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurosciences Therapeutic Area Unit , GSK Pharmaceuticals R&D , 898 Halei Road, Zhangjiang Hi-Tech Park , Pudong , Shanghai 201203 , P. R. China. Curated by ChEMBL | Assay Description Antagonist activity at CX3CR1 (unknown origin) | J Med Chem 61: 2518-2532 (2018) Article DOI: 10.1021/acs.jmedchem.7b01854 BindingDB Entry DOI: 10.7270/Q2959M1F | |||||||||||
More data for this Ligand-Target Pair |