Compile Data Set for Download or QSAR

Found 47 hits of kd for UniProtKB: P41148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endoplasmin (Canis familiaris)	BDBM50439625 (CHEMBL2419341) Show SMILES CO[C@H]1C[C@H](C)Cc2c(O)c(NC(=O)C(C)=CC=C[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)cc(O)c2N=CCCCNC(=O)Cc1ccc2N3CCC4OC5CC[N+]6=C(C5=CC4=C3C(C)(C)c2c1)C(C)(C)c1cc(ccc61)S([O-])(=O)=O |r,w:16.16,38.39,c:61,64,67,t:28| Show InChI InChI=1S/C63H78N6O13S/c1-34-26-42-54(48(70)33-45(56(42)73)67-60(74)35(2)14-13-15-51(79-9)57(82-61(64)75)37(4)28-36(3)55(72)52(27-34)80-10)66-23-12-11-22-65-53(71)30-38-16-18-46-43(29-38)62(5,6)58-40-32-41-50(81-49(40)20-24-68(46)58)21-25-69-47-19-17-39(83(76,77)78)31-44(47)63(7,8)59(41)69/h13-19,23,28-29,31-34,36,49-52,55,57,72H,11-12,20-22,24-27,30H2,1-10H3,(H6-,64,65,67,70,71,73,74,75,76,77,78)/b15-13?,35-14?,37-28+,66-23?/t34-,36+,49?,50?,51+,52+,55-,57+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					Assay Description Binding affinity to dog Grp94 by fluorescence polarization assay				J Med Chem 56: 6803-18 (2013) Article DOI: 10.1021/jm400619b BindingDB Entry DOI: 10.7270/Q2PN972K
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50439623 (CHEMBL2419342) Show SMILES Nc1ncnc2n(CCCNC(=S)Nc3ccc(c(c3)C(O)=O)-c3c4ccc(O)cc4oc4cc(=O)ccc34)c(Sc3cc4OCOc4cc3I)nc12 |(19.6,-8.98,;19.61,-10.53,;18.28,-11.3,;18.27,-12.85,;19.61,-13.62,;20.94,-12.85,;22.42,-13.33,;22.46,-14.87,;21.14,-15.68,;21.18,-17.22,;19.87,-18.02,;19.91,-19.56,;18.6,-20.37,;21.26,-20.3,;21.3,-21.84,;19.99,-22.63,;20.03,-24.17,;21.38,-24.92,;22.64,-24.21,;22.65,-22.56,;24.18,-24.21,;24.94,-22.88,;24.94,-25.54,;21.42,-26.46,;20.11,-27.26,;18.77,-26.54,;17.45,-27.34,;17.5,-28.88,;16.19,-29.69,;18.84,-29.6,;20.15,-28.8,;21.51,-29.54,;22.82,-28.71,;24.17,-29.44,;25.47,-28.63,;26.83,-29.36,;25.42,-27.09,;23.95,-26.54,;22.77,-27.18,;23.34,-12.07,;24.88,-12.07,;25.65,-10.73,;27.19,-10.74,;27.96,-9.41,;29.47,-9.09,;29.63,-7.55,;28.22,-6.92,;27.19,-8.07,;25.64,-8.07,;24.88,-9.41,;23.34,-9.41,;22.42,-10.81,;20.94,-11.3,)| Show InChI InChI=1S/C36H26IN7O7S2/c37-24-13-27-28(50-16-49-27)14-29(24)53-36-43-31-32(38)40-15-41-33(31)44(36)9-1-8-39-35(52)42-17-2-5-20(23(10-17)34(47)48)30-21-6-3-18(45)11-25(21)51-26-12-19(46)4-7-22(26)30/h2-7,10-15,45H,1,8-9,16H2,(H,47,48)(H2,38,40,41)(H2,39,42,52)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					Assay Description Binding affinity to dog Grp94 by fluorescence polarization assay				J Med Chem 56: 6803-18 (2013) Article DOI: 10.1021/jm400619b BindingDB Entry DOI: 10.7270/Q2PN972K
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279187 (CHEMBL4174059) Show SMILES Oc1cc(O)c(cc1Cc1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C22H18FNO3/c23-18-7-5-14(6-8-18)9-17-10-19(21(26)11-20(17)25)22(27)24-12-15-3-1-2-4-16(15)13-24/h1-8,10-11,25-26H,9,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279155 (CHEMBL4160774) Show SMILES Oc1cc(O)c(cc1Sc1ccccc1)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C21H17NO3S/c23-18-11-19(24)20(26-16-8-2-1-3-9-16)10-17(18)21(25)22-12-14-6-4-5-7-15(14)13-22/h1-11,23-24H,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279191 (CHEMBL4170618) Show SMILES Oc1cc(O)c(cc1Cc1ccc(Cl)cc1)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C22H18ClNO3/c23-18-7-5-14(6-8-18)9-17-10-19(21(26)11-20(17)25)22(27)24-12-15-3-1-2-4-16(15)13-24/h1-8,10-11,25-26H,9,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279185 (CHEMBL4173418) Show SMILES Oc1cc(O)c(cc1Cc1ccccc1)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C22H19NO3/c24-20-12-21(25)19(11-18(20)10-15-6-2-1-3-7-15)22(26)23-13-16-8-4-5-9-17(16)14-23/h1-9,11-12,24-25H,10,13-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Binding affinity towards vitronectin receptor (alpha V-beta3) was determined				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279186 (CHEMBL4165495) Show SMILES CN(c1ccccc1)c1ccc(O)c(c1)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C22H20N2O2/c1-23(18-9-3-2-4-10-18)19-11-12-21(25)20(13-19)22(26)24-14-16-7-5-6-8-17(16)15-24/h2-13,25H,14-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM227590 (PA1) Show SMILES Oc1cc(O)c(cc1Br)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C15H12BrNO3/c16-12-5-11(13(18)6-14(12)19)15(20)17-7-9-3-1-2-4-10(9)8-17/h1-6,18-19H,7-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279172 (CHEMBL4159747) Show SMILES Cc1ccc(Sc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)cc1C Show InChI InChI=1S/C23H21NO3S/c1-14-7-8-18(9-15(14)2)28-22-10-19(20(25)11-21(22)26)23(27)24-12-16-5-3-4-6-17(16)13-24/h3-11,25-26H,12-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279190 (CHEMBL4161657) Show SMILES Oc1ccccc1Sc1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1O Show InChI InChI=1S/C21H17NO4S/c23-16-7-3-4-8-19(16)27-20-9-15(17(24)10-18(20)25)21(26)22-11-13-5-1-2-6-14(13)12-22/h1-10,23-25H,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279159 (CHEMBL4177418) Show SMILES Cc1ccc(C)c(Sc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)c1 Show InChI InChI=1S/C23H21NO3S/c1-14-7-8-15(2)21(9-14)28-22-10-18(19(25)11-20(22)26)23(27)24-12-16-5-3-4-6-17(16)13-24/h3-11,25-26H,12-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279171 (CHEMBL4170382) Show SMILES Cc1ccc(Sc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)c(C)c1 Show InChI InChI=1S/C23H21NO3S/c1-14-7-8-21(15(2)9-14)28-22-10-18(19(25)11-20(22)26)23(27)24-12-16-5-3-4-6-17(16)13-24/h3-11,25-26H,12-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50439624 (CHEMBL1910764) Show SMILES CC(C)N(CCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)ncnc12)C(=S)Nc1ccc(c(c1)C(O)=O)-c1c2ccc(O)cc2oc2cc(=O)ccc12 |(24.17,-3.37,;24.17,-4.91,;25.5,-5.68,;22.84,-5.68,;21.5,-4.92,;21.5,-3.38,;20.16,-2.61,;20.16,-1.07,;21.08,.17,;22.62,.16,;23.39,1.49,;24.93,1.47,;25.71,2.81,;27.21,3.11,;27.38,4.64,;25.98,5.28,;24.95,4.14,;23.4,4.14,;22.63,2.82,;21.09,2.82,;20.17,1.42,;18.71,.95,;17.4,1.72,;17.41,3.26,;16.08,.96,;16.07,-.57,;17.39,-1.34,;18.7,-.59,;22.84,-7.22,;21.5,-8,;24.17,-7.99,;24.17,-9.53,;22.84,-10.31,;22.84,-11.85,;24.17,-12.61,;25.51,-11.84,;25.51,-10.3,;27.04,-11.84,;27.82,-13.17,;27.81,-10.5,;24.17,-14.14,;22.84,-14.92,;21.5,-14.15,;20.17,-14.93,;20.17,-16.47,;18.84,-17.24,;21.51,-17.24,;22.83,-16.47,;24.17,-17.24,;25.51,-16.46,;26.84,-17.23,;28.17,-16.46,;29.5,-17.23,;28.17,-14.92,;26.84,-14.15,;25.51,-14.92,)| Show InChI InChI=1S/C39H32IN7O7S2/c1-19(2)46(10-3-11-47-36-34(35(41)42-17-43-36)45-39(47)56-32-16-31-30(15-27(32)40)52-18-53-31)38(55)44-20-4-7-23(26(12-20)37(50)51)33-24-8-5-21(48)13-28(24)54-29-14-22(49)6-9-25(29)33/h4-9,12-17,19,48H,3,10-11,18H2,1-2H3,(H,44,55)(H,50,51)(H2,41,42,43)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					Assay Description Binding affinity to dog Grp94 by fluorescence polarization assay				J Med Chem 56: 6803-18 (2013) Article DOI: 10.1021/jm400619b BindingDB Entry DOI: 10.7270/Q2PN972K
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279156 (CHEMBL4169566) Show SMILES Oc1cc(O)c(cc1Sc1cc(Cl)cc(Cl)c1)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C21H15Cl2NO3S/c22-14-5-15(23)7-16(6-14)28-20-8-17(18(25)9-19(20)26)21(27)24-10-12-3-1-2-4-13(12)11-24/h1-9,25-26H,10-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279158 (CHEMBL4175693) Show SMILES COc1cccc(Sc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)c1 Show InChI InChI=1S/C22H19NO4S/c1-27-16-7-4-8-17(9-16)28-21-10-18(19(24)11-20(21)25)22(26)23-12-14-5-2-3-6-15(14)13-23/h2-11,24-25H,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279173 (CHEMBL4162694) Show SMILES Cc1ccc(Cc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)cc1 Show InChI InChI=1S/C23H21NO3/c1-15-6-8-16(9-7-15)10-19-11-20(22(26)12-21(19)25)23(27)24-13-17-4-2-3-5-18(17)14-24/h2-9,11-12,25-26H,10,13-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279170 (CHEMBL4162283) Show SMILES Oc1cc(O)c(cc1Sc1ccc(Cl)cc1Cl)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C21H15Cl2NO3S/c22-14-5-6-19(16(23)7-14)28-20-8-15(17(25)9-18(20)26)21(27)24-10-12-3-1-2-4-13(12)11-24/h1-9,25-26H,10-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279188 (CHEMBL4172951) Show SMILES Oc1cc(O)c(cc1Cc1ccccc1Cl)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C22H18ClNO3/c23-19-8-4-3-5-14(19)9-17-10-18(21(26)11-20(17)25)22(27)24-12-15-6-1-2-7-16(15)13-24/h1-8,10-11,25-26H,9,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279189 (CHEMBL4165074) Show SMILES Oc1ccc(Sc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)cc1 Show InChI InChI=1S/C21H17NO4S/c23-15-5-7-16(8-6-15)27-20-9-17(18(24)10-19(20)25)21(26)22-11-13-3-1-2-4-14(13)12-22/h1-10,23-25H,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM501630 (US11028041, Compound 21) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1cccnc1Cc1ccccc1 Show InChI InChI=1S/C22H20ClNO4/c1-28-22(27)20-16(21(23)19(26)13-18(20)25)10-9-15-8-5-11-24-17(15)12-14-6-3-2-4-7-14/h2-8,11,13,25-26H,9-10,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmin (Canis familiaris)	BDBM501629 (US11028041, Compound 20) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1ccc(N)cc1Cc1ccccc1 Show InChI InChI=1S/C23H22ClNO4/c1-29-23(28)21-18(22(24)20(27)13-19(21)26)10-8-15-7-9-17(25)12-16(15)11-14-5-3-2-4-6-14/h2-7,9,12-13,26-27H,8,10-11,25H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM501628 (US11028041, Compound 19) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1cc(N)ccc1Cc1ccccc1 Show InChI InChI=1S/C23H22ClNO4/c1-29-23(28)21-18(22(24)20(27)13-19(21)26)10-8-16-12-17(25)9-7-15(16)11-14-5-3-2-4-6-14/h2-7,9,12-13,26-27H,8,10-11,25H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM501631 (US11028041, Compound 22) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1cc(O)ccc1Cc1ccccc1 Show InChI InChI=1S/C23H21ClO5/c1-29-23(28)21-18(22(24)20(27)13-19(21)26)10-8-16-12-17(25)9-7-15(16)11-14-5-3-2-4-6-14/h2-7,9,12-13,25-27H,8,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM501632 (US11028041, Compound 23) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1ccc(O)cc1Cc1ccccc1 Show InChI InChI=1S/C23H21ClO5/c1-29-23(28)21-18(22(24)20(27)13-19(21)26)10-8-15-7-9-17(25)12-16(15)11-14-5-3-2-4-6-14/h2-7,9,12-13,25-27H,8,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM501640 (US11028041, Compound 31) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1cccnc1Cc1ccc(F)cc1 Show InChI InChI=1S/C22H19ClFNO4/c1-29-22(28)20-16(21(23)19(27)12-18(20)26)9-6-14-3-2-10-25-17(14)11-13-4-7-15(24)8-5-13/h2-5,7-8,10,12,26-27H,6,9,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50450701 (CHEMBL4168274) Show SMILES NC(=O)c1ccc(cc1N[C@H]1CC[C@H](O)CC1)-n1cccc1Cc1ccccc1O |r,wU:10.10,wD:13.14,(45.82,-28.46,;47.15,-27.69,;47.15,-26.16,;48.49,-28.46,;48.49,-30,;49.83,-30.77,;51.16,-30,;51.16,-28.46,;49.82,-27.69,;49.82,-26.16,;51.16,-25.38,;51.16,-23.84,;52.49,-23.07,;53.83,-23.84,;55.16,-23.07,;53.83,-25.38,;52.49,-26.16,;52.49,-30.77,;52.65,-32.3,;54.15,-32.61,;54.92,-31.28,;53.89,-30.14,;54.29,-28.66,;55.78,-28.26,;56.86,-29.35,;58.35,-28.95,;58.75,-27.47,;57.66,-26.38,;56.17,-26.77,;55.08,-25.68,)| Show InChI InChI=1S/C24H27N3O3/c25-24(30)21-12-9-19(15-22(21)26-17-7-10-20(28)11-8-17)27-13-3-5-18(27)14-16-4-1-2-6-23(16)29/h1-6,9,12-13,15,17,20,26,28-29H,7-8,10-11,14H2,(H2,25,30)/t17-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114516 BindingDB Entry DOI: 10.7270/Q2TQ65N5
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM501625 (US11028041, Compound 16) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1cc(OC)ccc1Cc1ccccc1 Show InChI InChI=1S/C24H23ClO5/c1-29-18-10-8-16(12-15-6-4-3-5-7-15)17(13-18)9-11-19-22(24(28)30-2)20(26)14-21(27)23(19)25/h3-8,10,13-14,26-27H,9,11-12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50087813 (CHEMBL3426786) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCC(=O)NC1=CC(=O)C(OC)=CC1=O |c:25,t:19| Show InChI InChI=1S/C18H16ClNO8/c1-27-14-7-10(21)9(5-11(14)22)20-15(25)4-3-8-16(18(26)28-2)12(23)6-13(24)17(8)19/h5-7,23-24H,3-4H2,1-2H3,(H,20,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a
Sloan-Kettering Curated by ChEMBL					Assay Description Binding affinity to canine full-length His-tagged GRP94 (28 to 754 residues lacking 287 to 327 residues) expressed in Escherichia coli by tryptophan ...				J Med Chem 58: 3922-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00197 BindingDB Entry DOI: 10.7270/Q2CC12DD
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50087813 (CHEMBL3426786) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCC(=O)NC1=CC(=O)C(OC)=CC1=O |c:25,t:19| Show InChI InChI=1S/C18H16ClNO8/c1-27-14-7-10(21)9(5-11(14)22)20-15(25)4-3-8-16(18(26)28-2)12(23)6-13(24)17(8)19/h5-7,23-24H,3-4H2,1-2H3,(H,20,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of FITC-geldanamycin binding to canine GRP94 incubated for 5 hrs by fluorescence polarization assay				J Med Chem 61: 9513-9533 (2018) Article DOI: 10.1021/acs.jmedchem.8b00800 BindingDB Entry DOI: 10.7270/Q2BK1FZW
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50450703 (CHEMBL4159086 | US11028041, Compound 30) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1ccccc1Cc1ccc(F)cc1 Show InChI InChI=1S/C23H20ClFO4/c1-29-23(28)21-18(22(24)20(27)13-19(21)26)11-8-15-4-2-3-5-16(15)12-14-6-9-17(25)10-7-14/h2-7,9-10,13,26-27H,8,11-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmin (Canis familiaris)	BDBM501633 (US11028041, Compound 24) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1cccc(O)c1Cc1ccccc1 Show InChI InChI=1S/C23H21ClO5/c1-29-23(28)21-16(22(24)20(27)13-19(21)26)11-10-15-8-5-9-18(25)17(15)12-14-6-3-2-4-7-14/h2-9,13,25-27H,10-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM501623 (US11028041, Compound 6) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1ccccc1Cc1ccccc1 Show InChI InChI=1S/C23H21ClO4/c1-28-23(27)21-18(22(24)20(26)14-19(21)25)12-11-16-9-5-6-10-17(16)13-15-7-3-2-4-8-15/h2-10,14,25-26H,11-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmin (Canis familiaris)	BDBM501626 (US11028041, Compound 17) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1ccc(OC)cc1Cc1ccccc1 Show InChI InChI=1S/C24H23ClO5/c1-29-18-10-8-16(17(13-18)12-15-6-4-3-5-7-15)9-11-19-22(24(28)30-2)20(26)14-21(27)23(19)25/h3-8,10,13-14,26-27H,9,11-12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM501627 (US11028041, Compound 18) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1cccc(OC)c1Cc1ccccc1 Show InChI InChI=1S/C24H23ClO5/c1-29-21-10-6-9-16(18(21)13-15-7-4-3-5-8-15)11-12-17-22(24(28)30-2)19(26)14-20(27)23(17)25/h3-10,14,26-27H,11-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279160 (CHEMBL4176780) Show SMILES CCOC(=O)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1O Show InChI InChI=1S/C18H17NO5/c1-2-24-18(23)14-7-13(15(20)8-16(14)21)17(22)19-9-11-5-3-4-6-12(11)10-19/h3-8,20-21H,2,9-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50087812 (CHEMBL3426787) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1nccn1Cc1ccccc1 Show InChI InChI=1S/C20H19ClN2O4/c1-27-20(26)18-14(19(21)16(25)11-15(18)24)7-8-17-22-9-10-23(17)12-13-5-3-2-4-6-13/h2-6,9-11,24-25H,7-8,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of FITC-geldanamycin binding to canine GRP94 incubated for 5 hrs by fluorescence polarization assay				J Med Chem 61: 9513-9533 (2018) Article DOI: 10.1021/acs.jmedchem.8b00800 BindingDB Entry DOI: 10.7270/Q2BK1FZW
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmin (Canis familiaris)	BDBM21220 ((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...) Show SMILES CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C12H16N6O4/c1-2-14-11(21)8-6(19)7(20)12(22-8)18-4-17-5-9(13)15-3-16-10(5)18/h3-4,6-8,12,19-20H,2H2,1H3,(H,14,21)(H2,13,15,16)/t6-,7+,8-,12+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114516 BindingDB Entry DOI: 10.7270/Q2TQ65N5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmin (Canis familiaris)	BDBM501638 (US11028041, Compound 29) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1ccccc1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C23H20Cl2O4/c1-29-23(28)21-18(22(25)20(27)13-19(21)26)11-8-15-4-2-3-5-16(15)12-14-6-9-17(24)10-7-14/h2-7,9-10,13,26-27H,8,11-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM501636 (US11028041, Compound 27) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1ccccc1Cc1ccccc1Cl Show InChI InChI=1S/C23H20Cl2O4/c1-29-23(28)21-17(22(25)20(27)13-19(21)26)11-10-14-6-2-3-7-15(14)12-16-8-4-5-9-18(16)24/h2-9,13,26-27H,10-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM501634 (US11028041, Compound 25) Show SMILES CCOc1ccccc1Cc1ccccc1CCc1c(Cl)c(O)cc(O)c1C(=O)OC Show InChI InChI=1S/C25H25ClO5/c1-3-31-22-11-7-6-10-18(22)14-17-9-5-4-8-16(17)12-13-19-23(25(29)30-2)20(27)15-21(28)24(19)26/h4-11,15,27-28H,3,12-14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM501635 (US11028041, Compound 26) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1ccccc1Cc1ccccc1OC Show InChI InChI=1S/C24H23ClO5/c1-29-21-10-6-5-9-17(21)13-16-8-4-3-7-15(16)11-12-18-22(24(28)30-2)19(26)14-20(27)23(18)25/h3-10,14,26-27H,11-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279157 (CHEMBL4168916) Show SMILES Oc1cc(O)c(cc1N1CCc2ccccc12)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C23H20N2O3/c26-21-12-22(27)20(25-10-9-15-5-3-4-8-19(15)25)11-18(21)23(28)24-13-16-6-1-2-7-17(16)14-24/h1-8,11-12,26-27H,9-10,13-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9.89E+3	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Binding affinity towards alpha4-beta2 nicotinic receptor was determined in rat brain membrane using [3H]cytisine as radioligand				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50279174 (CHEMBL4172281) Show SMILES COC(=O)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1O Show InChI InChI=1S/C17H15NO5/c1-23-17(22)13-6-12(14(19)7-15(13)20)16(21)18-8-10-4-2-3-5-11(10)9-18/h2-7,19-20H,8-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM501624 (US11028041, Compound 7) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1cccc(Cc2ccccc2)c1 Show InChI InChI=1S/C23H21ClO4/c1-28-23(27)21-18(22(24)20(26)14-19(21)25)11-10-16-8-5-9-17(13-16)12-15-6-3-2-4-7-15/h2-9,13-14,25-26H,10-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM501637 (US11028041, Compound 28) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1ccccc1Cc1cccc(Cl)c1 Show InChI InChI=1S/C23H20Cl2O4/c1-29-23(28)21-18(22(25)20(27)13-19(21)26)10-9-15-6-2-3-7-16(15)11-14-5-4-8-17(24)12-14/h2-8,12-13,26-27H,9-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The assay was performed in 96-well black, flat-bottom plates with a final volume of 100 μL. 25 μL of assay buffer (20 mM HEPES, pH 7.3, 50 ...				US Patent US11028041 (2021) BindingDB Entry DOI: 10.7270/Q2GQ71WX
					More data for this Ligand-Target Pair
Endoplasmin (Canis familiaris)	BDBM50450703 (CHEMBL4159086 | US11028041, Compound 30) Show SMILES COC(=O)c1c(O)cc(O)c(Cl)c1CCc1ccccc1Cc1ccc(F)cc1 Show InChI InChI=1S/C23H20ClFO4/c1-29-23(28)21-18(22(24)20(27)13-19(21)26)11-8-15-4-2-3-5-16(15)12-14-6-9-17(25)10-7-14/h2-7,9-10,13,26-27H,8,11-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	3.92E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114516 BindingDB Entry DOI: 10.7270/Q2TQ65N5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmin (Canis familiaris)	BDBM50279161 (CHEMBL4168694) Show SMILES Oc1cc(O)c(cc1C(=O)N1Cc2ccccc2C1)-c1ccccc1 Show InChI InChI=1S/C21H17NO3/c23-19-11-20(24)18(10-17(19)14-6-2-1-3-7-14)21(25)22-12-15-8-4-5-9-16(15)13-22/h1-11,23-24H,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of FITC-GDA from recombinant canine Grp94 expressed in baculovirus infected Sf21 insect cells after 24 hrs by fluorescence polarization ...				ACS Med Chem Lett 8: 1013-1018 (2017) Article DOI: 10.1021/acsmedchemlett.7b00193 BindingDB Entry DOI: 10.7270/Q2VQ3552
					More data for this Ligand-Target Pair