Compile Data Set for Download or QSAR

Found 6 hits of ec50 for UniProtKB: P42858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Huntingtin (Homo sapiens (Human))	BDBM50405601 (CHEMBL1240830) Show SMILES CCCCC(C)CP(O)(=O)O[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C18H35N2O6P/c1-3-4-8-14(2)13-27(24,25)26-16(10-5-6-11-19)17(21)20-12-7-9-15(20)18(22)23/h14-16H,3-13,19H2,1-2H3,(H,22,23)(H,24,25)/t14?,15-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...				Citation and Details
					More data for this Ligand-Target Pair
Huntingtin (Homo sapiens (Human))	BDBM50405602 (CHEMBL1240890) Show SMILES C[C@H](OP(O)(=O)CCCCc1ccccc1)C(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C18H26NO6P/c1-14(17(20)19-12-7-11-16(19)18(21)22)25-26(23,24)13-6-5-10-15-8-3-2-4-9-15/h2-4,8-9,14,16H,5-7,10-13H2,1H3,(H,21,22)(H,23,24)/t14-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...				Citation and Details
					More data for this Ligand-Target Pair
Huntingtin (Homo sapiens (Human))	BDBM50257750 (CHEMBL494325 | N-allyl-6-bromoquinazolin-4-amine |...) Show SMILES Brc1ccc2ncnc(NCC=C)c2c1 Show InChI InChI=1S/C11H10BrN3/c1-2-5-13-11-9-6-8(12)3-4-10(9)14-7-15-11/h2-4,6-7H,1,5H2,(H,13,14,15)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...				Citation and Details
					More data for this Ligand-Target Pair
Huntingtin (Homo sapiens (Human))	BDBM50257751 (CHEMBL494326 | N-benzyl-6-bromoquinazolin-4-amine ...) Show SMILES Brc1ccc2ncnc(NCc3ccccc3)c2c1 Show InChI InChI=1S/C15H12BrN3/c16-12-6-7-14-13(8-12)15(19-10-18-14)17-9-11-4-2-1-3-5-11/h1-8,10H,9H2,(H,17,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
Columbia University Curated by ChEMBL					Assay Description Inhibition of Huntingtin protein (unknown origin) aggregation by yeast based assay				Bioorg Med Chem Lett 19: 1715-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P
					More data for this Ligand-Target Pair
Huntingtin (Homo sapiens (Human))	BDBM50257750 (CHEMBL494325 | N-allyl-6-bromoquinazolin-4-amine |...) Show SMILES Brc1ccc2ncnc(NCC=C)c2c1 Show InChI InChI=1S/C11H10BrN3/c1-2-5-13-11-9-6-8(12)3-4-10(9)14-7-15-11/h2-4,6-7H,1,5H2,(H,13,14,15)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
Columbia University Curated by ChEMBL					Assay Description Inhibition of Huntingtin protein (unknown origin) aggregation by yeast based assay				Bioorg Med Chem Lett 19: 1715-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P
					More data for this Ligand-Target Pair
Huntingtin (Homo sapiens (Human))	BDBM50257749 (6-bromo-N-propylquinazolin-4-amine | CHEMBL449571) Show SMILES CCCNc1ncnc2ccc(Br)cc12 Show InChI InChI=1S/C11H12BrN3/c1-2-5-13-11-9-6-8(12)3-4-10(9)14-7-15-11/h3-4,6-7H,2,5H2,1H3,(H,13,14,15)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
Columbia University Curated by ChEMBL					Assay Description Inhibition of Huntingtin protein (unknown origin) aggregation by yeast based assay				Bioorg Med Chem Lett 19: 1715-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P
					More data for this Ligand-Target Pair