Compile Data Set for Download or QSAR

Found 5 hits of ic50 for UniProtKB: P18493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Bos taurus)	BDBM27709 (2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin...) Show SMILES Cc1cccc2c1nc(CCCN1CCC(=CC1)c1ccc(F)cc1)[nH]c2=O |c:16| Show InChI InChI=1S/C23H24FN3O/c1-16-4-2-5-20-22(16)25-21(26-23(20)28)6-3-13-27-14-11-18(12-15-27)17-7-9-19(24)10-8-17/h2,4-5,7-11H,3,6,12-15H2,1H3,(H,25,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair				3D Structure (crystal)
Poly [ADP-ribose] polymerase 1 (Bos taurus)	BDBM27503 (5-AIQ | 5-amino-1,2-dihydroisoquinolin-1-one | 5-a...) Show SMILES Nc1cccc2c1cc[nH]c2=O Show InChI InChI=1S/C9H8N2O/c10-8-3-1-2-7-6(8)4-5-11-9(7)12/h1-5H,10H2,(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of calf thymus PARP1				J Med Chem 52: 868-77 (2009) Article DOI: 10.1021/jm8013629 BindingDB Entry DOI: 10.7270/Q25M65KB
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Bos taurus)	BDBM27503 (5-AIQ | 5-amino-1,2-dihydroisoquinolin-1-one | 5-a...) Show SMILES Nc1cccc2c1cc[nH]c2=O Show InChI InChI=1S/C9H8N2O/c10-8-3-1-2-7-6(8)4-5-11-9(7)12/h1-5H,10H2,(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of calf thymus PARP-1				Bioorg Med Chem 21: 5218-27 (2013) Article DOI: 10.1016/j.bmc.2013.06.031 BindingDB Entry DOI: 10.7270/Q2BP047D
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Bos taurus)	BDBM27500 (5,6-dihydrophenanthridin-6-one | 5H-Phenanthridin-...) Show SMILES O=c1[nH]c2ccccc2c2ccccc12 Show InChI InChI=1S/C13H9NO/c15-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)14-13/h1-8H,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of calf thymus ARTD1 assessed as incorporation of [Ade-U-14C]-NAD+ after 10 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 18-22 (2014) Article DOI: 10.1021/ml400292s BindingDB Entry DOI: 10.7270/Q2SB477R
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Bos taurus)	BDBM50446131 (CHEMBL3108871) Show SMILES O=c1[nH]c2sccc2c2ccccc12 Show InChI InChI=1S/C11H7NOS/c13-10-8-4-2-1-3-7(8)9-5-6-14-11(9)12-10/h1-6H,(H,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of bovine ARTD1 assessed as incorporation of [adenine-2,8-3H]NAD after 1 hr by liquid scintillation spectrometric analysis				ACS Med Chem Lett 5: 18-22 (2014) Article DOI: 10.1021/ml400292s BindingDB Entry DOI: 10.7270/Q2SB477R
					More data for this Ligand-Target Pair