Compile Data Set for Download or QSAR

Found 20 hits of ic50 for UniProtKB: P50591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44372 (2-(dichloromethyl)-4-(4-methylphenyl)-6-(methylthi...) Show SMILES CSc1nc(nc(n1)-c1ccc(C)cc1)C(Cl)Cl Show InChI InChI=1S/C12H11Cl2N3S/c1-7-3-5-8(6-4-7)10-15-11(9(13)14)17-12(16-10)18-2/h3-6,9H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	372	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2639N51
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44372 (2-(dichloromethyl)-4-(4-methylphenyl)-6-(methylthi...) Show SMILES CSc1nc(nc(n1)-c1ccc(C)cc1)C(Cl)Cl Show InChI InChI=1S/C12H11Cl2N3S/c1-7-3-5-8(6-4-7)10-15-11(9(13)14)17-12(16-10)18-2/h3-6,9H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	602	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2639N51
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44374 (2-(dichloromethyl)-4-(methylthio)-6-(4-nitrophenyl...) Show SMILES CSc1nc(nc(n1)-c1ccc(cc1)[N+]([O-])=O)C(Cl)Cl Show InChI InChI=1S/C11H8Cl2N4O2S/c1-20-11-15-9(14-10(16-11)8(12)13)6-2-4-7(5-3-6)17(18)19/h2-5,8H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	683	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2639N51
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44374 (2-(dichloromethyl)-4-(methylthio)-6-(4-nitrophenyl...) Show SMILES CSc1nc(nc(n1)-c1ccc(cc1)[N+]([O-])=O)C(Cl)Cl Show InChI InChI=1S/C11H8Cl2N4O2S/c1-20-11-15-9(14-10(16-11)8(12)13)6-2-4-7(5-3-6)17(18)19/h2-5,8H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	806	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q22F7KT5
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44372 (2-(dichloromethyl)-4-(4-methylphenyl)-6-(methylthi...) Show SMILES CSc1nc(nc(n1)-c1ccc(C)cc1)C(Cl)Cl Show InChI InChI=1S/C12H11Cl2N3S/c1-7-3-5-8(6-4-7)10-15-11(9(13)14)17-12(16-10)18-2/h3-6,9H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q22F7KT5
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44372 (2-(dichloromethyl)-4-(4-methylphenyl)-6-(methylthi...) Show SMILES CSc1nc(nc(n1)-c1ccc(C)cc1)C(Cl)Cl Show InChI InChI=1S/C12H11Cl2N3S/c1-7-3-5-8(6-4-7)10-15-11(9(13)14)17-12(16-10)18-2/h3-6,9H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q22F7KT5
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44369 (2-(4-chlorophenyl)-4-(ethylthio)-6-(1-pyrrolidinyl...) Show SMILES CCSc1cc(nc(n1)-c1ccc(Cl)cc1)N1CCCC1 Show InChI InChI=1S/C16H18ClN3S/c1-2-21-15-11-14(20-9-3-4-10-20)18-16(19-15)12-5-7-13(17)8-6-12/h5-8,11H,2-4,9-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q22F7KT5
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44370 (4-methoxy-6-phenyl-1H-pyrimidine-2-thione | MLS-03...) Show SMILES COc1cc(nc(=S)[nH]1)-c1ccccc1 Show InChI InChI=1S/C11H10N2OS/c1-14-10-7-9(12-11(15)13-10)8-5-3-2-4-6-8/h2-7H,1H3,(H,12,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q22F7KT5
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44371 (2-(ethylthio)-6-phenyl-1H-pyrimidin-4-one | 2-ethy...) Show SMILES CCSc1nc(cc(=O)[nH]1)-c1ccccc1 Show InChI InChI=1S/C12H12N2OS/c1-2-16-12-13-10(8-11(15)14-12)9-6-4-3-5-7-9/h3-8H,2H2,1H3,(H,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q22F7KT5
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44373 (2-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]sulf...) Show SMILES CC(Sc1nc(cc(n1)C(F)(F)F)-c1ccccc1)C(=O)N1CCCC1 Show InChI InChI=1S/C18H18F3N3OS/c1-12(16(25)24-9-5-6-10-24)26-17-22-14(13-7-3-2-4-8-13)11-15(23-17)18(19,20)21/h2-4,7-8,11-12H,5-6,9-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q22F7KT5
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44375 (MLS-0390927.0001 | [2-(4-methylsulfanyl-6-phenyl-1...) Show SMILES CSc1nc(nc(n1)-c1ccccc1OC(C)=O)-c1ccccc1 Show InChI InChI=1S/C18H15N3O2S/c1-12(22)23-15-11-7-6-10-14(15)17-19-16(20-18(21-17)24-2)13-8-4-3-5-9-13/h3-11H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q22F7KT5
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44376 (2-(methylthio)-4,6-diphenyl-1,3,5-triazine | 2-(me...) Show SMILES CSc1nc(nc(n1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C16H13N3S/c1-20-16-18-14(12-8-4-2-5-9-12)17-15(19-16)13-10-6-3-7-11-13/h2-11H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q22F7KT5
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44377 (2-(methylthio)-4-phenyl-6-propan-2-yl-1,3,5-triazi...) Show SMILES CSc1nc(nc(n1)-c1ccccc1)C(C)C Show InChI InChI=1S/C13H15N3S/c1-9(2)11-14-12(16-13(15-11)17-3)10-7-5-4-6-8-10/h4-9H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q22F7KT5
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44377 (2-(methylthio)-4-phenyl-6-propan-2-yl-1,3,5-triazi...) Show SMILES CSc1nc(nc(n1)-c1ccccc1)C(C)C Show InChI InChI=1S/C13H15N3S/c1-9(2)11-14-12(16-13(15-11)17-3)10-7-5-4-6-8-10/h4-9H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2639N51
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44376 (2-(methylthio)-4,6-diphenyl-1,3,5-triazine | 2-(me...) Show SMILES CSc1nc(nc(n1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C16H13N3S/c1-20-16-18-14(12-8-4-2-5-9-12)17-15(19-16)13-10-6-3-7-11-13/h2-11H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2639N51
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44375 (MLS-0390927.0001 | [2-(4-methylsulfanyl-6-phenyl-1...) Show SMILES CSc1nc(nc(n1)-c1ccccc1OC(C)=O)-c1ccccc1 Show InChI InChI=1S/C18H15N3O2S/c1-12(22)23-15-11-7-6-10-14(15)17-19-16(20-18(21-17)24-2)13-8-4-3-5-9-13/h3-11H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2639N51
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44373 (2-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]sulf...) Show SMILES CC(Sc1nc(cc(n1)C(F)(F)F)-c1ccccc1)C(=O)N1CCCC1 Show InChI InChI=1S/C18H18F3N3OS/c1-12(16(25)24-9-5-6-10-24)26-17-22-14(13-7-3-2-4-8-13)11-15(23-17)18(19,20)21/h2-4,7-8,11-12H,5-6,9-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2639N51
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44371 (2-(ethylthio)-6-phenyl-1H-pyrimidin-4-one | 2-ethy...) Show SMILES CCSc1nc(cc(=O)[nH]1)-c1ccccc1 Show InChI InChI=1S/C12H12N2OS/c1-2-16-12-13-10(8-11(15)14-12)9-6-4-3-5-7-9/h3-8H,2H2,1H3,(H,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2639N51
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44369 (2-(4-chlorophenyl)-4-(ethylthio)-6-(1-pyrrolidinyl...) Show SMILES CCSc1cc(nc(n1)-c1ccc(Cl)cc1)N1CCCC1 Show InChI InChI=1S/C16H18ClN3S/c1-2-21-15-11-14(20-9-3-4-10-20)18-16(19-15)12-5-7-13(17)8-6-12/h5-8,11H,2-4,9-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2639N51
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10 (Homo sapiens (Human))	BDBM44370 (4-methoxy-6-phenyl-1H-pyrimidine-2-thione | MLS-03...) Show SMILES COc1cc(nc(=S)[nH]1)-c1ccccc1 Show InChI InChI=1S/C11H10N2OS/c1-14-10-7-9(12-11(15)13-10)8-5-3-2-4-6-8/h2-7H,1H3,(H,12,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2639N51
					More data for this Ligand-Target Pair