Found 51 hits of ic50 for UniProtKB: P32301 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50241203
(CHEMBL414357 | HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGS...)Show SMILES [H][C@](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@@]1([H])C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N[C@@H](CO)C(N)=O |r| Show InChI InChI=1S/C184H282N50O60S/c1-16-94(10)147(178(289)213-114(52-58-144(257)258)163(274)218-121(73-101-77-195-105-39-24-23-38-103(101)105)168(279)215-116(68-90(2)3)165(276)205-107(41-26-28-61-186)158(269)219-122(75-134(189)243)154(265)198-79-135(244)196-83-139(248)231-63-30-43-129(231)175(286)225-127(87-238)174(285)223-125(85-236)155(266)200-80-136(245)202-96(12)181(292)233-65-32-45-131(233)183(294)234-66-33-46-132(234)182(293)232-64-31-44-130(232)176(287)222-124(84-235)150(190)261)229-170(281)119(71-99-34-19-17-20-35-99)217-166(277)117(69-91(4)5)214-159(270)108(42-29-62-194-184(191)192)212-177(288)146(93(8)9)228-151(262)95(11)203-156(267)111(49-55-141(251)252)208-161(272)112(50-56-142(253)254)209-162(273)113(51-57-143(255)256)210-164(275)115(59-67-295-15)211-160(271)110(47-53-133(188)242)207-157(268)106(40-25-27-60-185)206-172(283)126(86-237)224-167(278)118(70-92(6)7)216-169(280)123(76-145(259)260)220-173(284)128(88-239)226-180(291)149(98(14)241)230-171(282)120(72-100-36-21-18-22-37-100)221-179(290)148(97(13)240)227-138(247)82-199-153(264)109(48-54-140(249)250)204-137(246)81-197-152(263)104(187)74-102-78-193-89-201-102/h17-24,34-39,77-78,89-98,104,106-132,146-149,195,235-241H,16,25-33,40-76,79-88,185-187H2,1-15H3,(H2,188,242)(H2,189,243)(H2,190,261)(H,193,201)(H,196,244)(H,197,263)(H,198,265)(H,199,264)(H,200,266)(H,202,245)(H,203,267)(H,204,246)(H,205,276)(H,206,283)(H,207,268)(H,208,272)(H,209,273)(H,210,275)(H,211,271)(H,212,288)(H,213,289)(H,214,270)(H,215,279)(H,216,280)(H,217,277)(H,218,274)(H,219,269)(H,220,284)(H,221,290)(H,222,287)(H,223,285)(H,224,278)(H,225,286)(H,226,291)(H,227,247)(H,228,262)(H,229,281)(H,230,282)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H,257,258)(H,259,260)(H4,191,192,194)/t94-,95-,96-,97+,98+,104-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,146-,147-,148-,149-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
SungKyunKwan University
Curated by ChEMBL
| Assay Description
Displacement of [125I]exendin-4 from GLP1 receptor in rat RINm5F cells after 2 hrs by gamma counting |
J Med Chem 52: 6889-96 (2009)
Article DOI: 10.1021/jm901153x
BindingDB Entry DOI: 10.7270/Q2RJ4JNM |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50314037
(CHEMBL1092704)Show SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)[C@H](C)CCC(=O)NCCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O |r| Show InChI InChI=1S/C208H319N49O65S/c1-19-106(10)169(199(315)237-132(58-65-165(284)285)185(301)241-138(82-114-89-219-123-42-27-26-41-118(114)123)189(305)239-134(77-102(2)3)187(303)229-124(43-28-30-69-209)180(296)242-139(87-154(212)269)176(292)222-91-156(271)220-95-160(275)254-72-33-46-146(254)195(311)247-143(98-260)194(310)246-142(97-259)177(293)224-92-157(272)226-109(13)202(318)256-74-35-48-148(256)204(320)257-75-36-49-149(257)203(319)255-73-34-47-147(255)196(312)245-141(96-258)172(213)288)252-190(306)136(80-112-37-22-20-23-38-112)240-188(304)135(78-103(4)5)238-181(297)126(45-32-71-218-206(214)215)236-198(314)168(105(8)9)251-173(289)108(12)227-178(294)129(55-62-162(278)279)232-183(299)130(56-63-163(280)281)233-184(300)131(57-64-164(282)283)234-186(302)133(67-76-323-18)235-182(298)128(53-59-153(211)268)231-179(295)125(44-29-31-70-217-155(270)60-50-107(11)119-51-52-120-167-121(86-152(267)208(119,120)17)207(16)68-66-117(265)83-115(207)84-150(167)266)230-192(308)144(99-261)248-197(313)151(79-104(6)7)322-205(321)140(88-166(286)287)244-193(309)145(100-262)249-201(317)171(111(15)264)253-191(307)137(81-113-39-24-21-25-40-113)243-200(316)170(110(14)263)250-159(274)94-223-175(291)127(54-61-161(276)277)228-158(273)93-221-174(290)122(210)85-116-90-216-101-225-116/h20-27,37-42,89-90,101-111,115,117,119-122,124-152,167-171,219,258-267H,19,28-36,43-88,91-100,209-210H2,1-18H3,(H2,211,268)(H2,212,269)(H2,213,288)(H,216,225)(H,217,270)(H,220,271)(H,221,290)(H,222,292)(H,223,291)(H,224,293)(H,226,272)(H,227,294)(H,228,273)(H,229,303)(H,230,308)(H,231,295)(H,232,299)(H,233,300)(H,234,302)(H,235,298)(H,236,314)(H,237,315)(H,238,297)(H,239,305)(H,240,304)(H,241,301)(H,242,296)(H,243,316)(H,244,309)(H,245,312)(H,246,310)(H,247,311)(H,248,313)(H,249,317)(H,250,274)(H,251,289)(H,252,306)(H,253,307)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,286,287)(H4,214,215,218)/t106-,107+,108-,109-,110+,111+,115-,117+,119+,120-,121-,122-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150+,151-,152-,167-,168-,169-,170-,171-,207-,208+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a |
SungKyunKwan University
Curated by ChEMBL
| Assay Description
Displacement of [125I]exendin-4 from GLP1 receptor in rat RINm5F cells after 2 hrs by gamma counting |
J Med Chem 52: 6889-96 (2009)
Article DOI: 10.1021/jm901153x
BindingDB Entry DOI: 10.7270/Q2RJ4JNM |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50314036
(CHEMBL1092373)Show SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)[C@H](C)CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O |r| Show InChI InChI=1S/C208H319N49O65S/c1-19-106(10)169(199(315)237-132(58-65-165(284)285)185(301)241-138(82-114-89-219-123-42-27-26-41-118(114)123)189(305)239-134(77-102(2)3)187(303)229-125(44-29-31-70-217-155(270)60-50-107(11)119-51-52-120-167-121(86-152(267)208(119,120)17)207(16)68-66-117(265)83-115(207)84-150(167)266)180(296)242-139(87-154(212)269)176(292)222-91-156(271)220-95-160(275)254-72-33-46-146(254)195(311)247-143(98-260)194(310)246-142(97-259)177(293)224-92-157(272)226-109(13)202(318)256-74-35-48-148(256)204(320)257-75-36-49-149(257)203(319)255-73-34-47-147(255)196(312)245-141(96-258)172(213)288)252-190(306)136(80-112-37-22-20-23-38-112)240-188(304)135(78-103(4)5)238-181(297)126(45-32-71-218-206(214)215)236-198(314)168(105(8)9)251-173(289)108(12)227-178(294)129(55-62-162(278)279)232-183(299)130(56-63-163(280)281)233-184(300)131(57-64-164(282)283)234-186(302)133(67-76-323-18)235-182(298)128(53-59-153(211)268)231-179(295)124(43-28-30-69-209)230-192(308)144(99-261)248-197(313)151(79-104(6)7)322-205(321)140(88-166(286)287)244-193(309)145(100-262)249-201(317)171(111(15)264)253-191(307)137(81-113-39-24-21-25-40-113)243-200(316)170(110(14)263)250-159(274)94-223-175(291)127(54-61-161(276)277)228-158(273)93-221-174(290)122(210)85-116-90-216-101-225-116/h20-27,37-42,89-90,101-111,115,117,119-122,124-152,167-171,219,258-267H,19,28-36,43-88,91-100,209-210H2,1-18H3,(H2,211,268)(H2,212,269)(H2,213,288)(H,216,225)(H,217,270)(H,220,271)(H,221,290)(H,222,292)(H,223,291)(H,224,293)(H,226,272)(H,227,294)(H,228,273)(H,229,303)(H,230,308)(H,231,295)(H,232,299)(H,233,300)(H,234,302)(H,235,298)(H,236,314)(H,237,315)(H,238,297)(H,239,305)(H,240,304)(H,241,301)(H,242,296)(H,243,316)(H,244,309)(H,245,312)(H,246,310)(H,247,311)(H,248,313)(H,249,317)(H,250,274)(H,251,289)(H,252,306)(H,253,307)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,286,287)(H4,214,215,218)/t106-,107+,108-,109-,110+,111+,115-,117+,119+,120-,121-,122-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150+,151-,152-,167-,168-,169-,170-,171-,207-,208+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.480 | n/a | n/a | n/a | n/a | n/a | n/a |
SungKyunKwan University
Curated by ChEMBL
| Assay Description
Displacement of [125I]exendin-4 from GLP1 receptor in rat RINm5F cells after 2 hrs by gamma counting |
J Med Chem 52: 6889-96 (2009)
Article DOI: 10.1021/jm901153x
BindingDB Entry DOI: 10.7270/Q2RJ4JNM |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50314039
(CHEMBL1092706)Show SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)[C@H](C)CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O |r| Show InChI InChI=1S/C208H319N49O64S/c1-19-107(10)169(199(314)237-134(60-67-166(283)284)185(300)241-140(84-115-90-219-125-42-27-26-41-119(115)125)189(304)239-136(79-103(2)3)187(302)229-127(44-29-31-72-217-156(269)62-50-108(11)121-53-54-122-120-52-51-116-85-118(265)68-70-207(116,16)123(120)87-153(266)208(121,122)17)180(295)242-141(88-155(212)268)176(291)222-92-157(270)220-96-161(274)254-74-33-46-148(254)195(310)247-145(99-260)194(309)246-144(98-259)177(292)224-93-158(271)226-110(13)202(317)256-76-35-48-150(256)204(319)257-77-36-49-151(257)203(318)255-75-34-47-149(255)196(311)245-143(97-258)172(213)287)252-190(305)138(82-113-37-22-20-23-38-113)240-188(303)137(80-104(4)5)238-181(296)128(45-32-73-218-206(214)215)236-198(313)168(106(8)9)251-173(288)109(12)227-178(293)131(57-64-163(277)278)232-183(298)132(58-65-164(279)280)233-184(299)133(59-66-165(281)282)234-186(301)135(69-78-322-18)235-182(297)130(55-61-154(211)267)231-179(294)126(43-28-30-71-209)230-192(307)146(100-261)248-197(312)152(81-105(6)7)321-205(320)142(89-167(285)286)244-193(308)147(101-262)249-201(316)171(112(15)264)253-191(306)139(83-114-39-24-21-25-40-114)243-200(315)170(111(14)263)250-160(273)95-223-175(290)129(56-63-162(275)276)228-159(272)94-221-174(289)124(210)86-117-91-216-102-225-117/h20-27,37-42,90-91,102-112,116,118,120-124,126-153,168-171,219,258-266H,19,28-36,43-89,92-101,209-210H2,1-18H3,(H2,211,267)(H2,212,268)(H2,213,287)(H,216,225)(H,217,269)(H,220,270)(H,221,289)(H,222,291)(H,223,290)(H,224,292)(H,226,271)(H,227,293)(H,228,272)(H,229,302)(H,230,307)(H,231,294)(H,232,298)(H,233,299)(H,234,301)(H,235,297)(H,236,313)(H,237,314)(H,238,296)(H,239,304)(H,240,303)(H,241,300)(H,242,295)(H,243,315)(H,244,308)(H,245,311)(H,246,309)(H,247,310)(H,248,312)(H,249,316)(H,250,273)(H,251,288)(H,252,305)(H,253,306)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,285,286)(H4,214,215,218)/t107-,108+,109-,110-,111+,112+,116+,118+,120-,121+,122-,123-,124-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,168-,169-,170-,171-,207-,208+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.550 | n/a | n/a | n/a | n/a | n/a | n/a |
SungKyunKwan University
Curated by ChEMBL
| Assay Description
Displacement of [125I]exendin-4 from GLP1 receptor in rat RINm5F cells after 2 hrs by gamma counting |
J Med Chem 52: 6889-96 (2009)
Article DOI: 10.1021/jm901153x
BindingDB Entry DOI: 10.7270/Q2RJ4JNM |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50314041
(CHEMBL1092708)Show SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O |r| Show InChI InChI=1S/C208H319N49O63S/c1-19-108(10)169(199(313)237-135(60-67-166(282)283)185(299)241-141(86-116-91-219-126-42-27-26-41-120(116)126)189(303)239-137(81-104(2)3)187(301)229-128(44-29-31-74-217-156(268)62-50-109(11)122-53-54-123-121-52-51-117-87-119(265)68-71-207(117,16)124(121)69-72-208(122,123)17)180(294)242-142(89-155(212)267)176(290)222-93-157(269)220-97-161(273)254-76-33-46-149(254)195(309)247-146(100-260)194(308)246-145(99-259)177(291)224-94-158(270)226-111(13)202(316)256-78-35-48-151(256)204(318)257-79-36-49-152(257)203(317)255-77-34-47-150(255)196(310)245-144(98-258)172(213)286)252-190(304)139(84-114-37-22-20-23-38-114)240-188(302)138(82-105(4)5)238-181(295)129(45-32-75-218-206(214)215)236-198(312)168(107(8)9)251-173(287)110(12)227-178(292)132(57-64-163(276)277)232-183(297)133(58-65-164(278)279)233-184(298)134(59-66-165(280)281)234-186(300)136(70-80-321-18)235-182(296)131(55-61-154(211)266)231-179(293)127(43-28-30-73-209)230-192(306)147(101-261)248-197(311)153(83-106(6)7)320-205(319)143(90-167(284)285)244-193(307)148(102-262)249-201(315)171(113(15)264)253-191(305)140(85-115-39-24-21-25-40-115)243-200(314)170(112(14)263)250-160(272)96-223-175(289)130(56-63-162(274)275)228-159(271)95-221-174(288)125(210)88-118-92-216-103-225-118/h20-27,37-42,91-92,103-113,117,119,121-125,127-153,168-171,219,258-265H,19,28-36,43-90,93-102,209-210H2,1-18H3,(H2,211,266)(H2,212,267)(H2,213,286)(H,216,225)(H,217,268)(H,220,269)(H,221,288)(H,222,290)(H,223,289)(H,224,291)(H,226,270)(H,227,292)(H,228,271)(H,229,301)(H,230,306)(H,231,293)(H,232,297)(H,233,298)(H,234,300)(H,235,296)(H,236,312)(H,237,313)(H,238,295)(H,239,303)(H,240,302)(H,241,299)(H,242,294)(H,243,314)(H,244,307)(H,245,310)(H,246,308)(H,247,309)(H,248,311)(H,249,315)(H,250,272)(H,251,287)(H,252,304)(H,253,305)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H4,214,215,218)/t108-,109+,110-,111-,112+,113+,117+,119+,121-,122+,123-,124-,125-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,168-,169-,170-,171-,207-,208+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.580 | n/a | n/a | n/a | n/a | n/a | n/a |
SungKyunKwan University
Curated by ChEMBL
| Assay Description
Displacement of [125I]exendin-4 from GLP1 receptor in rat RINm5F cells after 2 hrs by gamma counting |
J Med Chem 52: 6889-96 (2009)
Article DOI: 10.1021/jm901153x
BindingDB Entry DOI: 10.7270/Q2RJ4JNM |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50314038
(CHEMBL1092705)Show SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)[C@H](C)CCC(=O)NCCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)CC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O |r| Show InChI InChI=1S/C232H357N49O69S/c1-22-118(10)191(221(343)261-150(64-72-186(312)313)207(329)265-156(91-127-101-243-141-45-30-29-44-133(127)141)211(333)263-152(86-114(2)3)209(331)253-143(47-32-34-79-241-176(298)67-54-120(12)135-56-58-137-189-139(98-172(294)232(135,137)20)230(18)77-74-132(290)93-129(230)95-169(189)292)202(324)266-157(99-174(235)296)198(320)246-103-177(299)244-107-181(303)278-81-36-49-164(278)217(339)271-161(110-284)216(338)270-160(109-283)199(321)248-104-178(300)250-122(14)224(346)280-83-38-51-166(280)226(348)281-84-39-52-167(281)225(347)279-82-37-50-165(279)218(340)269-159(108-282)194(236)316)276-212(334)154(89-125-40-25-23-26-41-125)264-210(332)153(87-115(4)5)262-203(325)144(48-35-80-242-228(237)238)260-220(342)190(117(8)9)275-195(317)121(13)251-200(322)147(61-69-183(306)307)256-205(327)148(62-70-184(308)309)257-206(328)149(63-71-185(310)311)258-208(330)151(75-85-351-21)259-204(326)146(59-65-173(234)295)255-201(323)142(46-31-33-78-240-175(297)66-53-119(11)134-55-57-136-188-138(97-171(293)231(134,136)19)229(17)76-73-131(289)92-128(229)94-168(188)291)254-214(336)162(111-285)272-219(341)170(88-116(6)7)350-227(349)158(100-187(314)315)268-215(337)163(112-286)273-223(345)193(124(16)288)277-213(335)155(90-126-42-27-24-28-43-126)267-222(344)192(123(15)287)274-180(302)106-247-197(319)145(60-68-182(304)305)252-179(301)105-245-196(318)140(233)96-130-102-239-113-249-130/h23-30,40-45,101-102,113-124,128-129,131-132,134-140,142-172,188-193,243,282-294H,22,31-39,46-100,103-112,233H2,1-21H3,(H2,234,295)(H2,235,296)(H2,236,316)(H,239,249)(H,240,297)(H,241,298)(H,244,299)(H,245,318)(H,246,320)(H,247,319)(H,248,321)(H,250,300)(H,251,322)(H,252,301)(H,253,331)(H,254,336)(H,255,323)(H,256,327)(H,257,328)(H,258,330)(H,259,326)(H,260,342)(H,261,343)(H,262,325)(H,263,333)(H,264,332)(H,265,329)(H,266,324)(H,267,344)(H,268,337)(H,269,340)(H,270,338)(H,271,339)(H,272,341)(H,273,345)(H,274,302)(H,275,317)(H,276,334)(H,277,335)(H,304,305)(H,306,307)(H,308,309)(H,310,311)(H,312,313)(H,314,315)(H4,237,238,242)/t118-,119+,120+,121-,122-,123+,124+,128-,129-,131+,132+,134+,135+,136-,137-,138-,139-,140-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168+,169+,170-,171-,172-,188-,189-,190-,191-,192-,193-,229-,230-,231+,232+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.18 | n/a | n/a | n/a | n/a | n/a | n/a |
SungKyunKwan University
Curated by ChEMBL
| Assay Description
Displacement of [125I]exendin-4 from GLP1 receptor in rat RINm5F cells after 2 hrs by gamma counting |
J Med Chem 52: 6889-96 (2009)
Article DOI: 10.1021/jm901153x
BindingDB Entry DOI: 10.7270/Q2RJ4JNM |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50604669
(CHEMBL5208485)Show SMILES FC(F)(F)c1ccc(cc1)-c1noc(CN2CCCC(CN3CCOCC3)C2)n1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01842
BindingDB Entry DOI: 10.7270/Q22V2M6R |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50314040
(CHEMBL1092707)Show SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)[C@H](C)CCC(=O)NCCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)CC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O |r| Show InChI InChI=1S/C232H357N49O67S/c1-22-120(10)191(221(341)261-154(68-76-188(310)311)207(327)265-160(95-129-103-243-145-45-30-29-44-135(129)145)211(331)263-156(90-116(2)3)209(329)253-147(47-32-34-83-241-178(296)71-54-122(12)139-60-62-141-137-58-56-131-97-134(290)78-81-230(131,18)143(137)100-174(292)232(139,141)20)202(322)266-161(101-176(235)294)198(318)246-105-179(297)244-109-183(301)278-85-36-49-168(278)217(337)271-165(112-284)216(336)270-164(111-283)199(319)248-106-180(298)250-124(14)224(344)280-87-38-51-170(280)226(346)281-88-39-52-171(281)225(345)279-86-37-50-169(279)218(338)269-163(110-282)194(236)314)276-212(332)158(93-127-40-25-23-26-41-127)264-210(330)157(91-117(4)5)262-203(323)148(48-35-84-242-228(237)238)260-220(340)190(119(8)9)275-195(315)123(13)251-200(320)151(65-73-185(304)305)256-205(325)152(66-74-186(306)307)257-206(326)153(67-75-187(308)309)258-208(328)155(79-89-349-21)259-204(324)150(63-69-175(234)293)255-201(321)146(46-31-33-82-240-177(295)70-53-121(11)138-59-61-140-136-57-55-130-96-133(289)77-80-229(130,17)142(136)99-173(291)231(138,140)19)254-214(334)166(113-285)272-219(339)172(92-118(6)7)348-227(347)162(102-189(312)313)268-215(335)167(114-286)273-223(343)193(126(16)288)277-213(333)159(94-128-42-27-24-28-43-128)267-222(342)192(125(15)287)274-182(300)108-247-197(317)149(64-72-184(302)303)252-181(299)107-245-196(316)144(233)98-132-104-239-115-249-132/h23-30,40-45,103-104,115-126,130-131,133-134,136-144,146-174,190-193,243,282-292H,22,31-39,46-102,105-114,233H2,1-21H3,(H2,234,293)(H2,235,294)(H2,236,314)(H,239,249)(H,240,295)(H,241,296)(H,244,297)(H,245,316)(H,246,318)(H,247,317)(H,248,319)(H,250,298)(H,251,320)(H,252,299)(H,253,329)(H,254,334)(H,255,321)(H,256,325)(H,257,326)(H,258,328)(H,259,324)(H,260,340)(H,261,341)(H,262,323)(H,263,331)(H,264,330)(H,265,327)(H,266,322)(H,267,342)(H,268,335)(H,269,338)(H,270,336)(H,271,337)(H,272,339)(H,273,343)(H,274,300)(H,275,315)(H,276,332)(H,277,333)(H,302,303)(H,304,305)(H,306,307)(H,308,309)(H,310,311)(H,312,313)(H4,237,238,242)/t120-,121+,122+,123-,124-,125+,126+,130+,131+,133+,134+,136-,137-,138+,139+,140-,141-,142-,143-,144-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,190-,191-,192-,193-,229-,230-,231+,232+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10.1 | n/a | n/a | n/a | n/a | n/a | n/a |
SungKyunKwan University
Curated by ChEMBL
| Assay Description
Displacement of [125I]exendin-4 from GLP1 receptor in rat RINm5F cells after 2 hrs by gamma counting |
J Med Chem 52: 6889-96 (2009)
Article DOI: 10.1021/jm901153x
BindingDB Entry DOI: 10.7270/Q2RJ4JNM |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50314042
(CHEMBL1092709)Show SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(=O)NCCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)CC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O |r| Show InChI InChI=1S/C232H357N49O65S/c1-22-122(10)191(221(339)261-156(68-76-188(308)309)207(325)265-162(99-131-105-243-147-45-30-29-44-137(131)147)211(329)263-158(94-118(2)3)209(327)253-149(47-32-34-87-241-178(294)71-54-124(12)141-60-62-143-139-58-56-133-101-136(290)78-83-230(133,18)145(139)80-85-232(141,143)20)202(320)266-163(103-176(235)292)198(316)246-107-179(295)244-111-183(299)278-89-36-49-170(278)217(335)271-167(114-284)216(334)270-166(113-283)199(317)248-108-180(296)250-126(14)224(342)280-91-38-51-172(280)226(344)281-92-39-52-173(281)225(343)279-90-37-50-171(279)218(336)269-165(112-282)194(236)312)276-212(330)160(97-129-40-25-23-26-41-129)264-210(328)159(95-119(4)5)262-203(321)150(48-35-88-242-228(237)238)260-220(338)190(121(8)9)275-195(313)125(13)251-200(318)153(65-73-185(302)303)256-205(323)154(66-74-186(304)305)257-206(324)155(67-75-187(306)307)258-208(326)157(81-93-347-21)259-204(322)152(63-69-175(234)291)255-201(319)148(46-31-33-86-240-177(293)70-53-123(11)140-59-61-142-138-57-55-132-100-135(289)77-82-229(132,17)144(138)79-84-231(140,142)19)254-214(332)168(115-285)272-219(337)174(96-120(6)7)346-227(345)164(104-189(310)311)268-215(333)169(116-286)273-223(341)193(128(16)288)277-213(331)161(98-130-42-27-24-28-43-130)267-222(340)192(127(15)287)274-182(298)110-247-197(315)151(64-72-184(300)301)252-181(297)109-245-196(314)146(233)102-134-106-239-117-249-134/h23-30,40-45,105-106,117-128,132-133,135-136,138-146,148-174,190-193,243,282-290H,22,31-39,46-104,107-116,233H2,1-21H3,(H2,234,291)(H2,235,292)(H2,236,312)(H,239,249)(H,240,293)(H,241,294)(H,244,295)(H,245,314)(H,246,316)(H,247,315)(H,248,317)(H,250,296)(H,251,318)(H,252,297)(H,253,327)(H,254,332)(H,255,319)(H,256,323)(H,257,324)(H,258,326)(H,259,322)(H,260,338)(H,261,339)(H,262,321)(H,263,329)(H,264,328)(H,265,325)(H,266,320)(H,267,340)(H,268,333)(H,269,336)(H,270,334)(H,271,335)(H,272,337)(H,273,341)(H,274,298)(H,275,313)(H,276,330)(H,277,331)(H,300,301)(H,302,303)(H,304,305)(H,306,307)(H,308,309)(H,310,311)(H4,237,238,242)/t122-,123+,124+,125-,126-,127+,128+,132+,133+,135+,136+,138-,139-,140+,141+,142-,143-,144-,145-,146-,148-,149-,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,190-,191-,192-,193-,229-,230-,231+,232+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 72.0 | n/a | n/a | n/a | n/a | n/a | n/a |
SungKyunKwan University
Curated by ChEMBL
| Assay Description
Displacement of [125I]exendin-4 from GLP1 receptor in rat RINm5F cells after 2 hrs by gamma counting |
J Med Chem 52: 6889-96 (2009)
Article DOI: 10.1021/jm901153x
BindingDB Entry DOI: 10.7270/Q2RJ4JNM |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393572
(CHEMBL2158488)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)C(C)C)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)C(C)C)cc1)C(O)=O)C(O)=O |r,wU:50.56,33.36,17.19,16.17,wD:50.72,17.75,(9.02,-36.38,;7.7,-37.17,;6.36,-36.42,;5.04,-37.21,;3.7,-36.46,;3.66,-34.93,;4.98,-34.13,;6.33,-34.88,;7.65,-34.09,;7.62,-32.55,;6.28,-31.8,;8.87,-31.64,;10.34,-32.12,;11.24,-30.88,;10.34,-29.63,;8.87,-30.1,;2.38,-37.26,;2.38,-38.8,;3.45,-39.91,;3.44,-41.45,;2.1,-42.21,;4.76,-42.23,;4.74,-43.77,;6.07,-44.55,;7.41,-43.79,;8.74,-44.57,;8.73,-46.11,;10.06,-46.88,;7.39,-46.87,;6.06,-46.09,;7.38,-48.41,;7.42,-42.24,;6.09,-41.47,;.84,-38.8,;.05,-40.09,;.77,-41.44,;-.02,-42.76,;-1.57,-42.73,;-2.37,-44.05,;-1.63,-45.4,;-.09,-45.43,;-2.57,-46.61,;-4.12,-46.57,;-4.64,-48.02,;-3.42,-48.96,;-2.15,-48.1,;-2.3,-41.38,;-3.84,-41.34,;-4.58,-39.98,;-1.5,-40.06,;.84,-37.26,;.07,-35.92,;.84,-34.59,;2.38,-34.59,;.07,-33.26,;.84,-31.93,;.07,-30.6,;-1.47,-30.6,;-2.24,-29.26,;-1.48,-27.93,;-2.25,-26.6,;.06,-27.93,;.83,-26.59,;.84,-29.26,;-2.24,-31.94,;-1.47,-33.27,;-.71,-37.26,;-1.48,-35.93,;-1.48,-38.59,;3.91,-38.8,;4.68,-40.13,;4.43,-37.73,)| Show InChI InChI=1S/C52H48N4O14S2/c1-27(2)43(57)53-33-17-11-29(12-18-33)45(59)55-51(49(63)64)41(31-15-21-35(37(25-31)67-5)69-47(61)39-9-7-23-71-39)52(50(65)66,56-46(60)30-13-19-34(20-14-30)54-44(58)28(3)4)42(51)32-16-22-36(38(26-32)68-6)70-48(62)40-10-8-24-72-40/h7-28,41-42H,1-6H3,(H,53,57)(H,54,58)(H,55,59)(H,56,60)(H,63,64)(H,65,66)/t41-,42+,51+,52- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50260245
(1,3-bis(4-(cyclopentanecarboxamido)benzamido)-2,4-...)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)C1C(NC(=O)c2ccc(NC(=O)C3CCCC3)cc2)(C(c2ccc(OC(=O)c3cccs3)c(OC)c2)C1(NC(=O)c1ccc(NC(=O)C2CCCC2)cc1)C(O)=O)C(O)=O |(19.44,-26.93,;20.21,-28.27,;21.75,-28.28,;22.52,-26.96,;24.06,-26.97,;24.82,-28.29,;24.05,-29.61,;22.51,-29.61,;21.73,-30.95,;20.19,-30.94,;19.42,-29.6,;19.42,-32.27,;17.89,-32.43,;17.57,-33.94,;18.9,-34.71,;20.05,-33.68,;24.06,-25.41,;25.6,-25.41,;25.61,-26.96,;26.95,-27.73,;28.49,-27.71,;26.94,-29.26,;25.61,-30.03,;25.6,-31.57,;26.92,-32.34,;26.92,-33.88,;25.59,-34.65,;24.26,-33.87,;25.58,-36.19,;24.34,-37.09,;24.8,-38.56,;26.34,-38.56,;26.82,-37.1,;28.27,-31.57,;28.27,-30.04,;25.6,-23.87,;25.59,-22.31,;24.82,-21,;25.59,-19.67,;27.13,-19.66,;27.89,-18.33,;29.43,-18.32,;30.21,-19.66,;30.2,-16.99,;31.73,-16.82,;32.05,-15.32,;30.71,-14.54,;29.56,-15.58,;27.89,-20.99,;29.43,-20.99,;30.21,-22.32,;27.13,-22.32,;24.06,-23.86,;24.04,-22.32,;22.69,-21.56,;21.15,-21.58,;22.69,-20.03,;24.01,-19.25,;24.01,-17.71,;22.68,-16.95,;22.68,-15.41,;24,-14.63,;25.34,-15.4,;24,-13.09,;25.24,-12.18,;24.76,-10.71,;23.22,-10.72,;22.75,-12.19,;21.34,-17.72,;21.35,-19.26,;22.52,-23.86,;21.75,-22.53,;21.74,-25.19,;27.15,-25.43,;27.9,-26.77,;27.93,-24.1,)| Show InChI InChI=1S/C56H52N4O14S2/c1-71-41-29-35(19-25-39(41)73-51(65)43-13-7-27-75-43)45-55(53(67)68,59-49(63)33-15-21-37(22-16-33)57-47(61)31-9-3-4-10-31)46(36-20-26-40(42(30-36)72-2)74-52(66)44-14-8-28-76-44)56(45,54(69)70)60-50(64)34-17-23-38(24-18-34)58-48(62)32-11-5-6-12-32/h7-8,13-32,45-46H,3-6,9-12H2,1-2H3,(H,57,61)(H,58,62)(H,59,63)(H,60,64)(H,67,68)(H,69,70) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393571
(CHEMBL2158489)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)C(C)(C)C)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)C(C)(C)C)cc1)C(O)=O)C(O)=O |r,wU:51.57,34.37,17.19,16.17,wD:51.74,17.77,(33.17,-34.99,;31.85,-35.78,;30.5,-35.03,;29.18,-35.82,;27.84,-35.07,;27.8,-33.54,;29.12,-32.74,;30.47,-33.49,;31.79,-32.7,;31.77,-31.16,;30.42,-30.41,;33.01,-30.25,;34.48,-30.73,;35.39,-29.48,;34.48,-28.24,;33.02,-28.71,;26.52,-35.86,;26.52,-37.4,;27.59,-38.52,;27.58,-40.06,;26.24,-40.82,;28.91,-40.84,;28.89,-42.37,;30.21,-43.15,;31.55,-42.4,;32.88,-43.17,;32.87,-44.71,;34.2,-45.49,;31.53,-45.48,;30.21,-44.7,;31.52,-47.02,;30.04,-45.87,;31.56,-40.85,;30.23,-40.07,;24.98,-37.4,;24.19,-38.7,;24.91,-40.05,;24.12,-41.37,;22.58,-41.34,;21.78,-42.65,;22.51,-44,;24.05,-44.04,;21.57,-45.22,;20.02,-45.18,;19.5,-46.63,;20.72,-47.57,;21.99,-46.7,;21.84,-39.98,;20.3,-39.94,;19.56,-38.59,;22.64,-38.67,;24.98,-35.87,;24.21,-34.53,;24.98,-33.2,;26.52,-33.2,;24.21,-31.86,;24.98,-30.54,;24.21,-29.2,;22.67,-29.2,;21.9,-27.87,;22.67,-26.54,;21.89,-25.2,;24.21,-26.53,;24.98,-27.87,;24.97,-25.2,;25.74,-26.53,;21.9,-30.55,;22.68,-31.87,;23.43,-35.87,;22.66,-34.53,;22.67,-37.2,;28.05,-37.4,;28.83,-38.74,;28.57,-36.34,)| Show InChI InChI=1S/C54H52N4O14S2/c1-51(2,3)47(63)55-33-19-13-29(14-20-33)43(59)57-53(49(65)66)41(31-17-23-35(37(27-31)69-7)71-45(61)39-11-9-25-73-39)54(50(67)68,58-44(60)30-15-21-34(22-16-30)56-48(64)52(4,5)6)42(53)32-18-24-36(38(28-32)70-8)72-46(62)40-12-10-26-74-40/h9-28,41-42H,1-8H3,(H,55,63)(H,56,64)(H,57,59)(H,58,60)(H,65,66)(H,67,68)/t41-,42+,53+,54- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50260246
(1,3-bis(4-(tert-butoxycarbonyl)benzamido)-2,4-bis(...)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)C1C(NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)(C(c2ccc(OC(=O)c3cccs3)c(OC)c2)C1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |(.32,-12.51,;1.08,-13.85,;2.62,-13.86,;3.39,-12.53,;4.93,-12.54,;5.69,-13.87,;4.93,-15.19,;3.38,-15.19,;2.61,-16.52,;1.07,-16.52,;.3,-15.18,;.3,-17.85,;-1.23,-18.01,;-1.55,-19.51,;-.22,-20.29,;.93,-19.26,;4.93,-10.99,;4.93,-9.45,;4.92,-7.9,;3.56,-7.14,;2.02,-7.16,;3.56,-5.61,;4.89,-4.84,;4.89,-3.3,;3.55,-2.53,;3.55,-.99,;4.88,-.21,;6.22,-.98,;4.87,1.33,;6.21,2.1,;7.53,2.89,;6.99,.77,;5.43,3.43,;2.22,-3.31,;2.23,-4.85,;6.47,-9.45,;6.46,-7.9,;5.7,-6.57,;6.46,-5.25,;8,-5.24,;8.77,-3.91,;10.31,-3.9,;11.08,-5.24,;11.07,-2.57,;12.6,-2.4,;12.92,-.9,;11.58,-.13,;10.44,-1.16,;8.77,-6.57,;10.31,-6.57,;11.08,-7.91,;8,-7.9,;6.47,-10.99,;6.48,-12.53,;7.83,-13.3,;9.37,-13.29,;7.82,-14.84,;6.48,-15.6,;6.47,-17.14,;7.8,-17.92,;7.8,-19.46,;6.46,-20.22,;5.13,-19.45,;6.45,-21.76,;5.12,-22.53,;3.77,-23.29,;5.88,-23.87,;4.36,-21.19,;9.14,-17.14,;9.15,-15.61,;8.02,-11.01,;8.77,-12.35,;8.8,-9.68,;3.39,-9.44,;2.62,-8.1,;2.61,-10.77,)| Show InChI InChI=1S/C54H52N4O16S2/c1-51(2,3)73-49(67)55-33-19-13-29(14-20-33)43(59)57-53(47(63)64)41(31-17-23-35(37(27-31)69-7)71-45(61)39-11-9-25-75-39)54(48(65)66,58-44(60)30-15-21-34(22-16-30)56-50(68)74-52(4,5)6)42(53)32-18-24-36(38(28-32)70-8)72-46(62)40-12-10-26-76-40/h9-28,41-42H,1-8H3,(H,55,67)(H,56,68)(H,57,59)(H,58,60)(H,63,64)(H,65,66) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50260246
(1,3-bis(4-(tert-butoxycarbonyl)benzamido)-2,4-bis(...)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)C1C(NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)(C(c2ccc(OC(=O)c3cccs3)c(OC)c2)C1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |(.32,-12.51,;1.08,-13.85,;2.62,-13.86,;3.39,-12.53,;4.93,-12.54,;5.69,-13.87,;4.93,-15.19,;3.38,-15.19,;2.61,-16.52,;1.07,-16.52,;.3,-15.18,;.3,-17.85,;-1.23,-18.01,;-1.55,-19.51,;-.22,-20.29,;.93,-19.26,;4.93,-10.99,;4.93,-9.45,;4.92,-7.9,;3.56,-7.14,;2.02,-7.16,;3.56,-5.61,;4.89,-4.84,;4.89,-3.3,;3.55,-2.53,;3.55,-.99,;4.88,-.21,;6.22,-.98,;4.87,1.33,;6.21,2.1,;7.53,2.89,;6.99,.77,;5.43,3.43,;2.22,-3.31,;2.23,-4.85,;6.47,-9.45,;6.46,-7.9,;5.7,-6.57,;6.46,-5.25,;8,-5.24,;8.77,-3.91,;10.31,-3.9,;11.08,-5.24,;11.07,-2.57,;12.6,-2.4,;12.92,-.9,;11.58,-.13,;10.44,-1.16,;8.77,-6.57,;10.31,-6.57,;11.08,-7.91,;8,-7.9,;6.47,-10.99,;6.48,-12.53,;7.83,-13.3,;9.37,-13.29,;7.82,-14.84,;6.48,-15.6,;6.47,-17.14,;7.8,-17.92,;7.8,-19.46,;6.46,-20.22,;5.13,-19.45,;6.45,-21.76,;5.12,-22.53,;3.77,-23.29,;5.88,-23.87,;4.36,-21.19,;9.14,-17.14,;9.15,-15.61,;8.02,-11.01,;8.77,-12.35,;8.8,-9.68,;3.39,-9.44,;2.62,-8.1,;2.61,-10.77,)| Show InChI InChI=1S/C54H52N4O16S2/c1-51(2,3)73-49(67)55-33-19-13-29(14-20-33)43(59)57-53(47(63)64)41(31-17-23-35(37(27-31)69-7)71-45(61)39-11-9-25-75-39)54(48(65)66,58-44(60)30-15-21-34(22-16-30)56-50(68)74-52(4,5)6)42(53)32-18-24-36(38(28-32)70-8)72-46(62)40-12-10-26-76-40/h9-28,41-42H,1-8H3,(H,55,67)(H,56,68)(H,57,59)(H,58,60)(H,63,64)(H,65,66) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393601
(CHEMBL2158498)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)C(C)NC(=O)OC(C)(C)C)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)C(C)NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |r,wU:40.43,17.19,16.17,57.63,wD:17.89,57.86,(6.45,-7.9,;5.13,-8.7,;3.78,-7.95,;2.46,-8.74,;1.12,-7.99,;1.09,-6.46,;2.4,-5.66,;3.76,-6.41,;5.08,-5.61,;5.05,-4.07,;3.7,-3.33,;6.3,-3.17,;7.76,-3.65,;8.67,-2.4,;7.77,-1.15,;6.3,-1.63,;-.19,-8.78,;-.2,-10.32,;.87,-11.44,;.86,-12.98,;-.48,-13.73,;2.19,-13.76,;2.17,-15.29,;3.5,-16.07,;4.84,-15.31,;6.17,-16.09,;7.5,-15.33,;7.51,-13.79,;8.83,-16.11,;8.82,-17.65,;10.17,-15.35,;11.5,-16.13,;11.49,-17.67,;12.84,-15.37,;14.17,-16.14,;15.51,-15.38,;14.16,-17.68,;15.49,-16.91,;4.84,-13.76,;3.52,-12.99,;-1.73,-10.32,;-2.53,-11.62,;-1.8,-12.97,;-2.59,-14.29,;-4.14,-14.26,;-4.94,-15.57,;-4.2,-16.92,;-2.66,-16.96,;-5.15,-18.14,;-6.69,-18.1,;-7.21,-19.54,;-6,-20.49,;-4.72,-19.62,;-4.88,-12.9,;-6.42,-12.86,;-7.15,-11.51,;-4.08,-11.59,;-1.74,-8.78,;-2.51,-7.45,;-1.74,-6.12,;-.2,-6.11,;-2.51,-4.78,;-1.74,-3.45,;-2.5,-2.12,;-4.05,-2.12,;-4.82,-.79,;-4.05,.55,;-2.51,.55,;-4.82,1.88,;-6.36,1.87,;-4.06,3.21,;-2.52,3.22,;-1.74,1.88,;-1.75,4.55,;-.21,4.55,;.56,5.89,;.56,3.22,;1.33,4.56,;-4.82,-3.47,;-4.04,-4.79,;-3.28,-8.78,;-4.05,-7.45,;-4.05,-10.12,;1.34,-10.32,;2.11,-11.65,;1.86,-9.26,)| Show InChI InChI=1S/C60H62N6O18S2/c1-31(61-55(77)83-57(3,4)5)47(67)63-37-21-15-33(16-22-37)49(69)65-59(53(73)74)45(35-19-25-39(41(29-35)79-9)81-51(71)43-13-11-27-85-43)60(54(75)76,46(59)36-20-26-40(42(30-36)80-10)82-52(72)44-14-12-28-86-44)66-50(70)34-17-23-38(24-18-34)64-48(68)32(2)62-56(78)84-58(6,7)8/h11-32,45-46H,1-10H3,(H,61,77)(H,62,78)(H,63,67)(H,64,68)(H,65,69)(H,66,70)(H,73,74)(H,75,76)/t31?,32?,45-,46+,59+,60- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393606
(CHEMBL2158421)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)C3CCCCC3)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)C2CCCCC2)cc1)C(O)=O)C(O)=O |r,wU:36.40,17.19,16.17,53.60,wD:53.80,17.83,(7.97,-36.73,;6.65,-37.52,;5.3,-36.77,;3.98,-37.56,;2.64,-36.81,;2.6,-35.28,;3.92,-34.48,;5.27,-35.23,;6.59,-34.44,;6.57,-32.9,;5.22,-32.15,;7.81,-31.99,;9.28,-32.47,;10.19,-31.23,;9.28,-29.98,;7.82,-30.45,;1.32,-37.61,;1.32,-39.15,;2.39,-40.26,;2.38,-41.8,;1.04,-42.56,;3.71,-42.58,;3.69,-44.12,;5.01,-44.9,;6.35,-44.14,;7.68,-44.92,;7.67,-46.46,;9,-47.23,;6.34,-47.22,;5.01,-46.44,;3.68,-47.19,;3.66,-48.73,;4.99,-49.51,;6.34,-48.76,;6.36,-42.59,;5.03,-41.82,;-.22,-39.15,;-1.01,-40.44,;-.29,-41.79,;-1.08,-43.11,;-2.62,-43.08,;-3.42,-44.4,;-2.69,-45.75,;-1.15,-45.78,;-3.63,-46.96,;-5.18,-46.92,;-5.7,-48.37,;-4.48,-49.31,;-3.21,-48.45,;-3.36,-41.73,;-4.9,-41.69,;-5.64,-40.33,;-2.56,-40.41,;-.22,-37.61,;-.99,-36.27,;-.22,-34.94,;1.32,-34.94,;-.99,-33.61,;-.22,-32.28,;-.99,-30.95,;-2.53,-30.95,;-3.3,-29.61,;-2.53,-28.28,;-3.31,-26.95,;-.99,-28.27,;-.22,-29.6,;1.31,-29.61,;2.09,-28.27,;1.32,-26.94,;-.23,-26.93,;-3.3,-32.29,;-2.52,-33.62,;-1.77,-37.61,;-2.54,-36.28,;-2.53,-38.94,;2.85,-39.15,;3.63,-40.48,;3.37,-38.08,)| Show InChI InChI=1S/C58H56N4O14S2/c1-73-43-31-37(21-27-41(43)75-53(67)45-15-9-29-77-45)47-57(55(69)70,61-51(65)35-17-23-39(24-18-35)59-49(63)33-11-5-3-6-12-33)48(38-22-28-42(44(32-38)74-2)76-54(68)46-16-10-30-78-46)58(47,56(71)72)62-52(66)36-19-25-40(26-20-36)60-50(64)34-13-7-4-8-14-34/h9-10,15-34,47-48H,3-8,11-14H2,1-2H3,(H,59,63)(H,60,64)(H,61,65)(H,62,66)(H,69,70)(H,71,72)/t47-,48+,57+,58- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393580
(CHEMBL2158410)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O |r| Show InChI InChI=1S/C186H275N51O59/c1-17-94(10)149(182(294)209-98(14)155(267)220-128(73-105-78-199-111-42-28-27-41-109(105)111)171(283)223-123(68-91(4)5)173(285)234-147(92(6)7)180(292)219-113(43-29-31-63-187)158(270)200-81-136(245)210-112(45-33-65-197-185(191)192)157(269)203-84-146(262)263)236-174(286)126(70-102-37-23-19-24-38-102)225-165(277)120(55-61-142(254)255)216-162(274)114(44-30-32-64-188)212-153(265)96(12)206-152(264)95(11)207-161(273)118(51-57-135(190)244)211-137(246)82-201-160(272)117(53-59-140(250)251)215-168(280)122(67-90(2)3)222-170(282)125(72-104-47-49-108(243)50-48-104)226-177(289)132(85-238)230-179(291)134(87-240)231-181(293)148(93(8)9)235-176(288)131(77-145(260)261)228-178(290)133(86-239)232-184(296)151(100(16)242)237-175(287)127(71-103-39-25-20-26-40-103)229-183(295)150(99(15)241)233-138(247)83-202-159(271)116(52-58-139(248)249)213-154(266)97(13)208-167(279)129(75-107-80-196-89-205-107)227-163(275)115(46-34-66-198-186(193)194)214-164(276)119(54-60-141(252)253)217-169(281)124(69-101-35-21-18-22-36-101)224-166(278)121(56-62-143(256)257)218-172(284)130(76-144(258)259)221-156(268)110(189)74-106-79-195-88-204-106/h18-28,35-42,47-50,78-80,88-100,110,112-134,147-151,199,238-243H,17,29-34,43-46,51-77,81-87,187-189H2,1-16H3,(H2,190,244)(H,195,204)(H,196,205)(H,200,270)(H,201,272)(H,202,271)(H,203,269)(H,206,264)(H,207,273)(H,208,279)(H,209,294)(H,210,245)(H,211,246)(H,212,265)(H,213,266)(H,214,276)(H,215,280)(H,216,274)(H,217,281)(H,218,284)(H,219,292)(H,220,267)(H,221,268)(H,222,282)(H,223,283)(H,224,278)(H,225,277)(H,226,289)(H,227,275)(H,228,290)(H,229,295)(H,230,291)(H,231,293)(H,232,296)(H,233,247)(H,234,285)(H,235,288)(H,236,286)(H,237,287)(H,248,249)(H,250,251)(H,252,253)(H,254,255)(H,256,257)(H,258,259)(H,260,261)(H,262,263)(H4,191,192,197)(H4,193,194,198)/t94-,95-,96-,97-,98-,99+,100+,110-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,147-,148-,149-,150-,151-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393576
(CHEMBL2158419)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)C3CC3)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)C2CC2)cc1)C(O)=O)C(O)=O |r,wU:50.57,33.37,17.19,16.17,wD:50.74,17.77,(10.64,-5.72,;9.32,-6.51,;7.97,-5.76,;6.66,-6.55,;5.32,-5.8,;5.28,-4.27,;6.59,-3.47,;7.95,-4.22,;9.27,-3.43,;9.24,-1.89,;7.89,-1.14,;10.49,-.98,;11.95,-1.46,;12.86,-.22,;11.96,1.03,;10.49,.56,;4,-6.6,;4,-8.14,;5.07,-9.25,;5.05,-10.79,;3.71,-11.55,;6.38,-11.57,;6.36,-13.11,;7.69,-13.89,;9.03,-13.13,;10.36,-13.91,;10.35,-15.45,;11.68,-16.22,;9.01,-16.21,;7.47,-16.2,;8.23,-17.54,;9.04,-11.58,;7.71,-10.81,;2.46,-8.14,;1.66,-9.43,;2.39,-10.78,;1.6,-12.1,;.05,-12.07,;-.75,-13.39,;-.01,-14.74,;1.53,-14.77,;-.95,-15.95,;-2.5,-15.91,;-3.02,-17.36,;-1.81,-18.3,;-.53,-17.44,;-.69,-10.72,;-2.22,-10.68,;-2.96,-9.32,;.12,-9.4,;2.45,-6.6,;1.68,-5.26,;2.45,-3.93,;3.99,-3.93,;1.68,-2.6,;2.46,-1.27,;1.69,.06,;.15,.06,;-.63,1.4,;.14,2.73,;-.63,4.06,;1.68,2.73,;3.01,1.96,;3.01,3.5,;-.62,-1.28,;.15,-2.61,;.91,-6.6,;.14,-5.27,;.14,-7.93,;5.53,-8.14,;6.3,-9.47,;6.05,-7.07,)| Show InChI InChI=1S/C52H44N4O14S2/c1-67-37-25-31(15-21-35(37)69-47(61)39-5-3-23-71-39)41-51(49(63)64,55-45(59)29-11-17-33(18-12-29)53-43(57)27-7-8-27)42(32-16-22-36(38(26-32)68-2)70-48(62)40-6-4-24-72-40)52(41,50(65)66)56-46(60)30-13-19-34(20-14-30)54-44(58)28-9-10-28/h3-6,11-28,41-42H,7-10H2,1-2H3,(H,53,57)(H,54,58)(H,55,59)(H,56,60)(H,63,64)(H,65,66)/t41-,42+,51+,52- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393575
(CHEMBL2158420)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)C3CCC3)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)C2CCC2)cc1)C(O)=O)C(O)=O |r,wU:51.58,34.38,17.19,16.17,wD:51.76,17.79,(35.31,-5.19,;33.98,-5.98,;32.64,-5.23,;31.32,-6.03,;29.98,-5.28,;29.94,-3.74,;31.26,-2.95,;32.61,-3.69,;33.93,-2.9,;33.9,-1.36,;32.56,-.61,;35.15,-.46,;36.62,-.93,;37.52,.31,;36.62,1.56,;35.16,1.09,;28.66,-6.07,;28.66,-7.61,;29.73,-8.72,;29.72,-10.26,;28.38,-11.02,;31.04,-11.04,;31.03,-12.58,;32.35,-13.36,;33.69,-12.6,;35.02,-13.38,;35.01,-14.92,;36.34,-15.7,;33.68,-15.68,;32.2,-15.27,;31.79,-16.75,;33.27,-17.16,;33.7,-11.05,;32.37,-10.28,;27.12,-7.61,;26.33,-8.9,;27.05,-10.25,;26.26,-11.57,;24.71,-11.54,;23.91,-12.86,;24.65,-14.21,;26.19,-14.24,;23.71,-15.43,;22.16,-15.38,;21.64,-16.83,;22.86,-17.77,;24.13,-16.91,;23.98,-10.19,;22.44,-10.15,;21.7,-8.8,;24.78,-8.87,;27.12,-6.07,;26.35,-4.73,;27.12,-3.4,;28.66,-3.4,;26.35,-2.07,;27.12,-.74,;26.35,.59,;24.81,.59,;24.04,1.92,;24.8,3.26,;24.03,4.59,;26.35,3.26,;27.44,2.17,;28.52,3.26,;27.43,4.35,;24.04,-.75,;24.81,-2.08,;25.57,-6.07,;24.8,-4.74,;24.8,-7.4,;30.19,-7.61,;30.96,-8.94,;30.71,-6.54,)| Show InChI InChI=1S/C54H48N4O14S2/c1-69-39-27-33(17-23-37(39)71-49(63)41-11-5-25-73-41)43-53(51(65)66,57-47(61)31-13-19-35(20-14-31)55-45(59)29-7-3-8-29)44(34-18-24-38(40(28-34)70-2)72-50(64)42-12-6-26-74-42)54(43,52(67)68)58-48(62)32-15-21-36(22-16-32)56-46(60)30-9-4-10-30/h5-6,11-30,43-44H,3-4,7-10H2,1-2H3,(H,55,59)(H,56,60)(H,57,61)(H,58,62)(H,65,66)(H,67,68)/t43-,44+,53+,54- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50260246
(1,3-bis(4-(tert-butoxycarbonyl)benzamido)-2,4-bis(...)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)C1C(NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)(C(c2ccc(OC(=O)c3cccs3)c(OC)c2)C1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |(.32,-12.51,;1.08,-13.85,;2.62,-13.86,;3.39,-12.53,;4.93,-12.54,;5.69,-13.87,;4.93,-15.19,;3.38,-15.19,;2.61,-16.52,;1.07,-16.52,;.3,-15.18,;.3,-17.85,;-1.23,-18.01,;-1.55,-19.51,;-.22,-20.29,;.93,-19.26,;4.93,-10.99,;4.93,-9.45,;4.92,-7.9,;3.56,-7.14,;2.02,-7.16,;3.56,-5.61,;4.89,-4.84,;4.89,-3.3,;3.55,-2.53,;3.55,-.99,;4.88,-.21,;6.22,-.98,;4.87,1.33,;6.21,2.1,;7.53,2.89,;6.99,.77,;5.43,3.43,;2.22,-3.31,;2.23,-4.85,;6.47,-9.45,;6.46,-7.9,;5.7,-6.57,;6.46,-5.25,;8,-5.24,;8.77,-3.91,;10.31,-3.9,;11.08,-5.24,;11.07,-2.57,;12.6,-2.4,;12.92,-.9,;11.58,-.13,;10.44,-1.16,;8.77,-6.57,;10.31,-6.57,;11.08,-7.91,;8,-7.9,;6.47,-10.99,;6.48,-12.53,;7.83,-13.3,;9.37,-13.29,;7.82,-14.84,;6.48,-15.6,;6.47,-17.14,;7.8,-17.92,;7.8,-19.46,;6.46,-20.22,;5.13,-19.45,;6.45,-21.76,;5.12,-22.53,;3.77,-23.29,;5.88,-23.87,;4.36,-21.19,;9.14,-17.14,;9.15,-15.61,;8.02,-11.01,;8.77,-12.35,;8.8,-9.68,;3.39,-9.44,;2.62,-8.1,;2.61,-10.77,)| Show InChI InChI=1S/C54H52N4O16S2/c1-51(2,3)73-49(67)55-33-19-13-29(14-20-33)43(59)57-53(47(63)64)41(31-17-23-35(37(27-31)69-7)71-45(61)39-11-9-25-75-39)54(48(65)66,58-44(60)30-15-21-34(22-16-30)56-50(68)74-52(4,5)6)42(53)32-18-24-36(38(28-32)70-8)72-46(62)40-12-10-26-76-40/h9-28,41-42H,1-8H3,(H,55,67)(H,56,68)(H,57,59)(H,58,60)(H,63,64)(H,65,66) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393569
(CHEMBL2158494)Show SMILES CNC(=S)Nc1ccc(cc1)C(=O)N[C@@]1([C@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@](NC(=O)c2ccc(NC(=S)NC)cc2)([C@@H]1c1ccc(OC(=O)c2cccs2)c(OC)c1)C(O)=O)C(O)=O |r,wU:47.52,14.14,15.16,32.35,wD:32.70,14.73,(11.33,-15.19,;11.34,-13.65,;10.01,-12.87,;10.02,-11.33,;8.67,-13.63,;7.34,-12.86,;6,-13.61,;4.67,-12.83,;4.69,-11.3,;6.02,-10.53,;7.35,-11.31,;3.37,-10.52,;2.03,-11.28,;3.38,-8.98,;2.31,-7.86,;2.31,-6.32,;3.63,-5.53,;3.59,-4,;4.91,-3.2,;6.26,-3.95,;7.58,-3.16,;7.55,-1.62,;6.21,-.87,;8.8,-.71,;10.27,-1.19,;11.17,.06,;10.27,1.3,;8.8,.83,;6.29,-5.49,;7.63,-6.24,;8.95,-5.45,;4.97,-6.28,;.77,-6.33,;-0,-4.99,;.77,-3.66,;2.31,-3.66,;-0,-2.32,;.77,-1,;-0,.34,;-1.54,.34,;-2.31,1.67,;-1.55,3,;-.01,3.01,;-2.32,4.34,;-1.55,5.67,;-2.31,-1.01,;-1.54,-2.33,;.77,-7.86,;-.02,-9.16,;.7,-10.51,;-.09,-11.83,;-1.64,-11.8,;-2.44,-13.11,;-1.7,-14.46,;-.16,-14.5,;-2.64,-15.68,;-4.19,-15.64,;-4.71,-17.09,;-3.49,-18.03,;-2.22,-17.16,;-2.37,-10.44,;-3.91,-10.4,;-4.65,-9.05,;-1.57,-9.13,;-.78,-6.33,;-1.55,-4.99,;-1.55,-7.66,;3.84,-7.86,;4.61,-9.2,;4.36,-6.8,)| Show InChI InChI=1S/C48H42N6O12S4/c1-49-45(67)51-29-15-9-25(10-16-29)39(55)53-47(43(59)60)37(27-13-19-31(33(23-27)63-3)65-41(57)35-7-5-21-69-35)48(44(61)62,54-40(56)26-11-17-30(18-12-26)52-46(68)50-2)38(47)28-14-20-32(34(24-28)64-4)66-42(58)36-8-6-22-70-36/h5-24,37-38H,1-4H3,(H,53,55)(H,54,56)(H,59,60)(H,61,62)(H2,49,51,67)(H2,50,52,68)/t37-,38+,47+,48- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393603
(CHEMBL2158491)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)COCc3ccccc3)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)COCc2ccccc2)cc1)C(O)=O)C(O)=O |r,wU:39.43,17.19,16.17,56.63,wD:17.89,56.86,(31.96,-4.8,;30.64,-5.59,;29.29,-4.85,;27.97,-5.64,;26.64,-4.89,;26.6,-3.35,;27.91,-2.56,;29.27,-3.3,;30.59,-2.51,;30.56,-.97,;29.21,-.22,;31.81,-.07,;33.27,-.54,;34.18,.7,;33.28,1.95,;31.81,1.48,;25.32,-5.68,;25.32,-7.22,;26.38,-8.33,;26.37,-9.87,;25.03,-10.63,;27.7,-10.65,;27.68,-12.19,;29.01,-12.97,;30.35,-12.21,;31.68,-12.99,;31.67,-14.53,;33,-15.31,;30.33,-15.29,;30.32,-16.83,;28.98,-17.59,;28.97,-19.13,;27.63,-19.88,;27.62,-21.42,;28.95,-22.2,;30.29,-21.43,;30.29,-19.89,;30.36,-10.66,;29.03,-9.89,;23.78,-7.22,;22.98,-8.51,;23.71,-9.86,;22.92,-11.19,;21.37,-11.15,;20.57,-12.47,;21.31,-13.82,;22.85,-13.85,;20.36,-15.04,;18.82,-14.99,;18.3,-16.44,;19.51,-17.38,;20.79,-16.52,;20.63,-9.8,;19.09,-9.76,;18.36,-8.41,;21.44,-8.49,;23.77,-5.68,;23,-4.35,;23.77,-3.01,;25.31,-3.01,;23,-1.68,;23.78,-.35,;23.01,.98,;21.46,.98,;20.69,2.31,;21.46,3.65,;20.69,4.98,;23,3.65,;23.77,4.99,;25.31,4.99,;26.07,6.32,;27.62,6.32,;28.39,7.65,;27.61,9,;26.06,8.99,;25.3,7.65,;20.7,-.36,;21.47,-1.69,;22.23,-5.68,;21.46,-4.35,;21.46,-7.01,;26.85,-7.22,;27.62,-8.55,;27.37,-6.16,)| Show InChI InChI=1S/C62H52N4O16S2/c1-77-47-31-41(21-27-45(47)81-57(71)49-15-9-29-83-49)53-61(59(73)74,65-55(69)39-17-23-43(24-18-39)63-51(67)35-79-33-37-11-5-3-6-12-37)54(42-22-28-46(48(32-42)78-2)82-58(72)50-16-10-30-84-50)62(53,60(75)76)66-56(70)40-19-25-44(26-20-40)64-52(68)36-80-34-38-13-7-4-8-14-38/h3-32,53-54H,33-36H2,1-2H3,(H,63,67)(H,64,68)(H,65,69)(H,66,70)(H,73,74)(H,75,76)/t53-,54+,61+,62- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393574
(CHEMBL2158422)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(C)=O)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(C)=O)cc1)C(O)=O)C(O)=O |r,wU:16.17,48.54,31.34,17.19,wD:48.68,17.71,(32.36,-35.86,;31.04,-36.65,;29.69,-35.9,;28.37,-36.69,;27.03,-35.94,;27,-34.41,;28.31,-33.61,;29.67,-34.36,;30.98,-33.57,;30.96,-32.03,;29.61,-31.28,;32.2,-31.12,;33.67,-31.6,;34.58,-30.35,;33.67,-29.11,;32.21,-29.58,;25.71,-36.73,;25.71,-38.28,;26.78,-39.39,;26.77,-40.93,;25.43,-41.69,;28.1,-41.71,;28.08,-43.25,;29.4,-44.03,;30.75,-43.27,;32.07,-44.05,;32.06,-45.59,;30.72,-46.35,;33.39,-46.36,;30.75,-41.72,;29.43,-40.94,;24.17,-38.27,;23.38,-39.57,;24.1,-40.92,;23.31,-42.24,;21.77,-42.21,;20.97,-43.52,;21.71,-44.88,;23.24,-44.91,;20.76,-46.09,;19.21,-46.05,;18.69,-47.5,;19.91,-48.44,;21.18,-47.58,;21.03,-40.85,;19.49,-40.82,;18.75,-39.46,;21.83,-39.54,;24.17,-36.74,;23.4,-35.4,;24.17,-34.07,;25.71,-34.07,;23.4,-32.74,;24.17,-31.41,;23.4,-30.08,;21.86,-30.08,;21.09,-28.74,;21.86,-27.41,;23.4,-27.41,;21.08,-26.08,;21.09,-31.42,;21.87,-32.75,;22.63,-36.74,;21.86,-35.4,;21.86,-38.07,;27.25,-38.27,;28.02,-39.61,;27.77,-37.21,)| Show InChI InChI=1S/C48H40N4O14S2/c1-25(53)49-31-15-9-27(10-16-31)41(55)51-47(45(59)60)39(29-13-19-33(35(23-29)63-3)65-43(57)37-7-5-21-67-37)48(46(61)62,52-42(56)28-11-17-32(18-12-28)50-26(2)54)40(47)30-14-20-34(36(24-30)64-4)66-44(58)38-8-6-22-68-38/h5-24,39-40H,1-4H3,(H,49,53)(H,50,54)(H,51,55)(H,52,56)(H,59,60)(H,61,62)/t39-,40+,47+,48- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393588
(CHEMBL2158407)Show SMILES CCC(=O)Oc1ccc(cc1OC)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H](c2ccc(OC(=O)CC)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |r,wU:13.13,46.50,32.34,14.15,wD:46.68,14.71,(30.57,-26.73,;31.89,-25.94,;31.86,-24.4,;33.18,-23.6,;30.51,-23.65,;29.19,-24.44,;29.22,-25.99,;27.9,-26.78,;26.56,-26.03,;26.52,-24.49,;27.83,-23.7,;27.8,-22.16,;29.12,-21.36,;25.24,-26.82,;25.24,-28.36,;26.31,-29.47,;26.29,-31.01,;24.96,-31.77,;27.62,-31.79,;27.6,-33.33,;28.93,-34.11,;30.27,-33.35,;31.6,-34.13,;31.59,-35.67,;32.92,-36.45,;30.25,-36.43,;30.24,-37.97,;28.9,-38.73,;31.57,-38.75,;30.25,-39.51,;30.28,-31.8,;28.95,-31.03,;23.7,-28.36,;22.9,-29.65,;23.63,-31,;22.84,-32.33,;21.29,-32.29,;20.49,-33.61,;18.95,-33.57,;18.21,-32.22,;18.15,-34.89,;16.61,-34.85,;20.56,-30.94,;19.02,-30.9,;18.28,-29.55,;21.36,-29.63,;23.69,-26.82,;22.93,-25.49,;23.7,-24.15,;25.24,-24.15,;22.92,-22.82,;23.7,-21.49,;22.93,-20.16,;21.39,-20.16,;20.61,-18.83,;21.38,-17.49,;20.61,-16.16,;22.92,-17.49,;23.69,-16.15,;25.23,-16.15,;22.92,-14.82,;24.45,-14.81,;20.62,-21.5,;21.39,-22.83,;22.15,-26.82,;21.38,-25.49,;21.38,-28.15,;26.77,-28.36,;27.54,-29.69,;27.29,-27.3,)| Show InChI InChI=1S/C50H56N4O16/c1-11-37(55)67-33-23-17-29(25-35(33)65-9)39-49(43(59)60,53-41(57)27-13-19-31(20-14-27)51-45(63)69-47(3,4)5)40(30-18-24-34(36(26-30)66-10)68-38(56)12-2)50(39,44(61)62)54-42(58)28-15-21-32(22-16-28)52-46(64)70-48(6,7)8/h13-26,39-40H,11-12H2,1-10H3,(H,51,63)(H,52,64)(H,53,57)(H,54,58)(H,59,60)(H,61,62)/t39-,40+,49+,50- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393568
(CHEMBL2158495)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=S)Nc3cccc4ccccc34)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=S)Nc2cccc3ccccc23)cc1)C(O)=O)C(O)=O |r,wU:41.46,17.19,16.17,58.66,wD:17.95,58.92,(36.68,-8.09,;35.36,-8.88,;34.01,-8.13,;32.69,-8.92,;31.35,-8.17,;31.32,-6.64,;32.63,-5.84,;33.99,-6.59,;35.31,-5.79,;35.28,-4.25,;33.93,-3.51,;36.53,-3.35,;37.99,-3.83,;38.9,-2.58,;38,-1.33,;36.53,-1.81,;30.04,-8.96,;30.03,-10.5,;31.1,-11.62,;31.09,-13.16,;29.75,-13.92,;32.42,-13.94,;32.4,-15.47,;33.73,-16.25,;35.07,-15.49,;36.4,-16.27,;37.74,-15.51,;37.75,-13.97,;39.06,-16.29,;39.05,-17.83,;37.71,-18.59,;37.7,-20.12,;39.03,-20.9,;40.37,-20.13,;41.69,-20.9,;43.02,-20.14,;43.02,-18.6,;41.7,-17.84,;40.38,-18.6,;35.08,-13.95,;33.75,-13.17,;28.49,-10.5,;27.7,-11.8,;28.43,-13.15,;27.64,-14.47,;26.09,-14.44,;25.29,-15.75,;26.03,-17.1,;27.57,-17.14,;25.08,-18.32,;23.54,-18.28,;23.01,-19.73,;24.23,-20.67,;25.51,-19.8,;25.35,-13.08,;23.81,-13.04,;23.07,-11.69,;26.15,-11.77,;28.49,-8.96,;27.72,-7.63,;28.49,-6.3,;30.03,-6.29,;27.72,-4.96,;28.49,-3.63,;27.72,-2.3,;26.18,-2.3,;25.41,-.97,;26.18,.37,;27.72,.37,;25.4,1.7,;26.17,3.03,;27.72,3.03,;28.48,4.36,;27.71,5.7,;26.17,5.69,;25.4,6.99,;23.88,7,;23.12,5.67,;23.88,4.35,;25.4,4.35,;25.41,-3.65,;26.19,-4.97,;26.95,-8.96,;26.18,-7.63,;26.18,-10.3,;31.57,-10.5,;32.34,-11.84,;32.09,-9.44,)| Show InChI InChI=1S/C66H50N6O12S4/c1-81-51-35-41(25-31-49(51)83-59(75)53-19-9-33-87-53)55-65(61(77)78,71-57(73)39-21-27-43(28-22-39)67-63(85)69-47-17-7-13-37-11-3-5-15-45(37)47)56(42-26-32-50(52(36-42)82-2)84-60(76)54-20-10-34-88-54)66(55,62(79)80)72-58(74)40-23-29-44(30-24-40)68-64(86)70-48-18-8-14-38-12-4-6-16-46(38)48/h3-36,55-56H,1-2H3,(H,71,73)(H,72,74)(H,77,78)(H,79,80)(H2,67,69,85)(H2,68,70,86)/t55-,56+,65+,66- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393590
(CHEMBL2158404)Show SMILES CCOc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OCC)c2)[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |r,wU:36.39,18.20,17.18,54.60,wD:18.81,54.78,(25.6,-43.26,;24.85,-41.91,;25.65,-40.59,;24.9,-39.25,;25.69,-37.93,;24.97,-36.58,;23.42,-36.55,;22.62,-37.86,;23.35,-39.21,;22.55,-40.53,;21.01,-40.49,;20.21,-41.81,;20.16,-39.21,;18.62,-39.15,;18.2,-37.67,;19.48,-36.81,;20.69,-37.76,;25.76,-35.28,;25.76,-33.74,;24.99,-32.41,;25.76,-31.07,;27.3,-31.07,;24.99,-29.74,;25.76,-28.41,;24.99,-27.08,;23.45,-27.08,;22.68,-25.75,;23.44,-24.41,;22.67,-23.08,;24.98,-24.41,;25.75,-23.08,;27.29,-23.07,;24.98,-21.74,;26.51,-21.73,;22.68,-28.42,;23.45,-29.75,;27.3,-33.74,;28.62,-32.95,;29.96,-33.7,;31.28,-32.91,;31.25,-31.37,;32.57,-30.57,;33.92,-31.32,;35.24,-30.52,;33.95,-32.86,;32.72,-33.79,;33.22,-35.24,;34.76,-35.22,;35.21,-33.74,;29.9,-30.62,;29.86,-29.08,;31.18,-28.28,;31.15,-26.74,;28.58,-31.41,;27.3,-35.28,;28.37,-36.39,;28.36,-37.93,;27.02,-38.69,;29.68,-38.71,;29.66,-40.25,;30.99,-41.03,;32.33,-40.27,;33.66,-41.05,;33.65,-42.59,;34.98,-43.37,;32.31,-43.35,;32.3,-44.89,;30.96,-45.65,;33.63,-45.67,;32.31,-46.43,;32.34,-38.72,;31.01,-37.95,;28.83,-35.28,;29.6,-36.61,;29.35,-34.22,;24.21,-33.74,;23.44,-32.41,;23.44,-35.08,)| Show InChI InChI=1S/C56H56N4O16S2/c1-9-71-39-29-33(19-25-37(39)73-47(63)41-13-11-27-77-41)43-55(49(65)66,59-45(61)31-15-21-35(22-16-31)57-51(69)75-53(3,4)5)44(34-20-26-38(40(30-34)72-10-2)74-48(64)42-14-12-28-78-42)56(43,50(67)68)60-46(62)32-17-23-36(24-18-32)58-52(70)76-54(6,7)8/h11-30,43-44H,9-10H2,1-8H3,(H,57,69)(H,58,70)(H,59,61)(H,60,62)(H,65,66)(H,67,68)/t43-,44+,55+,56- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393602
(CHEMBL2158493)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)Cc3ccccc3)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)Cc2ccccc2)cc1)C(O)=O)C(O)=O |r,wU:37.41,17.19,16.17,54.61,wD:54.82,17.85,(33.8,-34.57,;32.48,-35.36,;31.14,-34.61,;29.82,-35.4,;28.48,-34.65,;28.44,-33.12,;29.76,-32.32,;31.11,-33.07,;32.43,-32.28,;32.4,-30.74,;31.06,-29.99,;33.65,-29.83,;35.12,-30.31,;36.02,-29.06,;35.12,-27.82,;33.65,-28.29,;27.16,-35.44,;27.16,-36.98,;28.23,-38.1,;28.22,-39.64,;26.88,-40.4,;29.54,-40.42,;29.52,-41.95,;30.85,-42.73,;32.19,-41.98,;33.52,-42.75,;33.51,-44.29,;34.84,-45.07,;32.17,-45.06,;32.16,-46.6,;30.82,-47.35,;30.81,-48.89,;32.14,-49.67,;33.49,-48.9,;33.49,-47.36,;32.2,-40.43,;30.87,-39.65,;25.62,-36.98,;24.83,-38.28,;25.55,-39.63,;24.76,-40.95,;23.21,-40.92,;22.41,-42.23,;23.15,-43.58,;24.69,-43.62,;22.21,-44.8,;20.66,-44.76,;20.14,-46.21,;21.36,-47.15,;22.63,-46.28,;22.48,-39.56,;20.94,-39.52,;20.2,-38.17,;23.28,-38.25,;25.62,-35.45,;24.85,-34.11,;25.62,-32.78,;27.16,-32.78,;24.85,-31.44,;25.62,-30.12,;24.85,-28.78,;23.31,-28.78,;22.54,-27.45,;23.3,-26.12,;22.53,-24.78,;24.84,-26.11,;25.61,-24.78,;27.15,-24.78,;27.91,-23.45,;27.14,-22.11,;25.59,-22.12,;24.83,-23.45,;22.54,-30.13,;23.31,-31.45,;24.07,-35.45,;23.3,-34.11,;23.3,-36.78,;28.69,-36.98,;29.46,-38.32,;29.21,-35.92,)| Show InChI InChI=1S/C60H48N4O14S2/c1-75-45-33-39(21-27-43(45)77-55(69)47-15-9-29-79-47)51-59(57(71)72,63-53(67)37-17-23-41(24-18-37)61-49(65)31-35-11-5-3-6-12-35)52(40-22-28-44(46(34-40)76-2)78-56(70)48-16-10-30-80-48)60(51,58(73)74)64-54(68)38-19-25-42(26-20-38)62-50(66)32-36-13-7-4-8-14-36/h3-30,33-34,51-52H,31-32H2,1-2H3,(H,61,65)(H,62,66)(H,63,67)(H,64,68)(H,71,72)(H,73,74)/t51-,52+,59+,60- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393605
(CHEMBL2158487)Show SMILES CCCC(=O)Nc1ccc(cc1)C(=O)N[C@@]1([C@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@](NC(=O)c2ccc(NC(=O)CCC)cc2)([C@@H]1c1ccc(OC(=O)c2cccs2)c(OC)c1)C(O)=O)C(O)=O |r,wU:33.36,49.54,15.15,16.17,wD:33.72,15.75,(31.19,-14.45,;32.53,-13.69,;33.86,-14.47,;35.2,-13.7,;36.53,-14.48,;35.21,-12.16,;33.88,-11.39,;32.54,-12.14,;31.21,-11.36,;31.23,-9.83,;32.56,-9.06,;33.89,-9.84,;29.9,-9.05,;28.56,-9.81,;29.92,-7.51,;28.85,-6.39,;28.85,-4.85,;30.17,-4.06,;30.13,-2.53,;31.44,-1.73,;32.8,-2.48,;34.12,-1.69,;34.09,-.15,;32.74,.6,;35.34,.76,;36.8,.28,;37.71,1.53,;36.81,2.77,;35.34,2.3,;32.82,-4.02,;34.17,-4.77,;35.49,-3.98,;31.51,-4.81,;27.3,-4.86,;26.53,-3.52,;27.3,-2.19,;28.84,-2.19,;26.53,-.85,;27.31,.47,;26.54,1.81,;25,1.81,;24.22,3.14,;24.99,4.47,;24.22,5.81,;26.53,4.48,;27.3,3.14,;28.84,3.15,;24.23,.46,;25,-.86,;27.31,-6.39,;26.51,-7.69,;27.24,-9.04,;26.45,-10.36,;24.9,-10.33,;24.1,-11.64,;24.84,-12.99,;26.38,-13.03,;23.9,-14.21,;22.35,-14.17,;21.83,-15.62,;23.04,-16.56,;24.32,-15.69,;24.16,-8.97,;22.63,-8.93,;21.89,-7.58,;24.97,-7.66,;25.76,-4.86,;24.99,-3.52,;24.99,-6.19,;30.38,-6.39,;31.15,-7.73,;30.9,-5.33,)| Show InChI InChI=1S/C52H48N4O14S2/c1-5-9-41(57)53-33-19-13-29(14-20-33)45(59)55-51(49(63)64)43(31-17-23-35(37(27-31)67-3)69-47(61)39-11-7-25-71-39)52(50(65)66,56-46(60)30-15-21-34(22-16-30)54-42(58)10-6-2)44(51)32-18-24-36(38(28-32)68-4)70-48(62)40-12-8-26-72-40/h7-8,11-28,43-44H,5-6,9-10H2,1-4H3,(H,53,57)(H,54,58)(H,55,59)(H,56,60)(H,63,64)(H,65,66)/t43-,44+,51+,52- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50260246
(1,3-bis(4-(tert-butoxycarbonyl)benzamido)-2,4-bis(...)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)C1C(NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)(C(c2ccc(OC(=O)c3cccs3)c(OC)c2)C1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |(.32,-12.51,;1.08,-13.85,;2.62,-13.86,;3.39,-12.53,;4.93,-12.54,;5.69,-13.87,;4.93,-15.19,;3.38,-15.19,;2.61,-16.52,;1.07,-16.52,;.3,-15.18,;.3,-17.85,;-1.23,-18.01,;-1.55,-19.51,;-.22,-20.29,;.93,-19.26,;4.93,-10.99,;4.93,-9.45,;4.92,-7.9,;3.56,-7.14,;2.02,-7.16,;3.56,-5.61,;4.89,-4.84,;4.89,-3.3,;3.55,-2.53,;3.55,-.99,;4.88,-.21,;6.22,-.98,;4.87,1.33,;6.21,2.1,;7.53,2.89,;6.99,.77,;5.43,3.43,;2.22,-3.31,;2.23,-4.85,;6.47,-9.45,;6.46,-7.9,;5.7,-6.57,;6.46,-5.25,;8,-5.24,;8.77,-3.91,;10.31,-3.9,;11.08,-5.24,;11.07,-2.57,;12.6,-2.4,;12.92,-.9,;11.58,-.13,;10.44,-1.16,;8.77,-6.57,;10.31,-6.57,;11.08,-7.91,;8,-7.9,;6.47,-10.99,;6.48,-12.53,;7.83,-13.3,;9.37,-13.29,;7.82,-14.84,;6.48,-15.6,;6.47,-17.14,;7.8,-17.92,;7.8,-19.46,;6.46,-20.22,;5.13,-19.45,;6.45,-21.76,;5.12,-22.53,;3.77,-23.29,;5.88,-23.87,;4.36,-21.19,;9.14,-17.14,;9.15,-15.61,;8.02,-11.01,;8.77,-12.35,;8.8,-9.68,;3.39,-9.44,;2.62,-8.1,;2.61,-10.77,)| Show InChI InChI=1S/C54H52N4O16S2/c1-51(2,3)73-49(67)55-33-19-13-29(14-20-33)43(59)57-53(47(63)64)41(31-17-23-35(37(27-31)69-7)71-45(61)39-11-9-25-75-39)54(48(65)66,58-44(60)30-15-21-34(22-16-30)56-50(68)74-52(4,5)6)42(53)32-18-24-36(38(28-32)70-8)72-46(62)40-12-10-26-76-40/h9-28,41-42H,1-8H3,(H,55,67)(H,56,68)(H,57,59)(H,58,60)(H,63,64)(H,65,66) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393585
(CHEMBL2158311)Show SMILES COc1cc(ccc1OC(=O)C12CC3CC(CC(C3)C1)C2)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H](c2ccc(OC(=O)C34CC5CC(CC(C5)C3)C4)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |r,wU:21.24,62.72,40.45,22.26,wD:62.90,22.93,TLB:9:11:14:18.16.17,THB:19:17:14:20.11.12,19:11:14:18.16.17,53:52:49:55.54.56,53:54:51.52.57:49,56:54:51:57.48.49,56:48:51:55.53.54,16:15:12:18.17.19,16:17:14.15.20:12,(17.48,-8.85,;16.16,-9.64,;16.19,-11.18,;14.88,-11.98,;14.91,-13.51,;16.25,-14.26,;17.57,-13.47,;17.55,-11.93,;18.87,-11.14,;20.22,-11.88,;21.53,-11.09,;20.24,-13.42,;18.9,-13.9,;18.9,-15.39,;17.71,-16.66,;19.21,-16.24,;20.61,-16.81,;21.63,-15.53,;20.23,-15.88,;21.64,-14,;19.2,-14.66,;13.6,-14.31,;13.59,-15.85,;14.66,-16.96,;14.65,-18.5,;13.31,-19.26,;15.98,-19.28,;15.96,-20.82,;17.29,-21.6,;18.63,-20.84,;19.96,-21.62,;19.95,-23.16,;21.28,-23.94,;18.61,-23.92,;18.6,-25.46,;17.26,-26.22,;19.93,-26.24,;18.6,-27,;18.64,-19.29,;17.31,-18.52,;12.06,-15.85,;11.26,-17.14,;11.99,-18.49,;11.2,-19.81,;9.65,-19.78,;8.85,-21.1,;7.31,-21.06,;6.57,-19.71,;6.51,-22.38,;5.08,-22.4,;4.62,-23.82,;3.08,-24.65,;4.64,-24.73,;5.79,-25.7,;7.16,-24.81,;5.72,-24.7,;7.65,-23.37,;5.13,-23.22,;8.91,-18.43,;7.37,-18.39,;6.64,-17.03,;9.71,-17.11,;12.05,-14.31,;11.28,-12.97,;12.05,-11.64,;13.59,-11.64,;11.28,-10.31,;12.05,-8.98,;11.29,-7.65,;9.74,-7.65,;8.97,-6.31,;9.74,-4.98,;8.97,-3.65,;11.28,-4.98,;12.05,-3.64,;13.59,-3.64,;11.27,-2.31,;12.8,-2.3,;8.97,-8.99,;9.75,-10.32,;10.51,-14.31,;9.74,-12.98,;9.74,-15.64,;15.13,-15.85,;15.9,-17.18,;15.65,-14.78,)| Show InChI InChI=1S/C66H76N4O16/c1-61(2,3)85-59(79)67-45-15-9-41(10-16-45)53(71)69-65(55(73)74)51(43-13-19-47(49(27-43)81-7)83-57(77)63-29-35-21-36(30-63)23-37(22-35)31-63)66(56(75)76,70-54(72)42-11-17-46(18-12-42)68-60(80)86-62(4,5)6)52(65)44-14-20-48(50(28-44)82-8)84-58(78)64-32-38-24-39(33-64)26-40(25-38)34-64/h9-20,27-28,35-40,51-52H,21-26,29-34H2,1-8H3,(H,67,79)(H,68,80)(H,69,71)(H,70,72)(H,73,74)(H,75,76)/t35?,36?,37?,38?,39?,40?,51-,52+,63?,64?,65+,66- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393566
(CHEMBL2158497)Show SMILES CCOC(=O)CNC(=O)Nc1ccc(cc1)C(=O)N[C@@]1([C@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@](NC(=O)c2ccc(NC(=O)NCC(=O)OCC)cc2)([C@@H]1c1ccc(OC(=O)c2cccs2)c(OC)c1)C(O)=O)C(O)=O |r,wU:57.62,19.19,20.21,37.40,wD:19.83,37.80,(36.12,-48.39,;36.13,-46.85,;37.47,-46.09,;37.48,-44.55,;36.15,-43.77,;38.81,-43.79,;38.82,-42.25,;37.5,-41.47,;37.51,-39.93,;36.16,-42.23,;34.83,-41.45,;33.49,-42.21,;32.16,-41.43,;32.18,-39.9,;33.51,-39.13,;34.84,-39.91,;30.85,-39.12,;29.51,-39.88,;30.86,-37.58,;29.8,-36.46,;29.8,-34.92,;31.12,-34.13,;31.08,-32.6,;32.39,-31.8,;33.75,-32.55,;35.07,-31.75,;35.04,-30.21,;33.69,-29.47,;36.29,-29.31,;37.75,-29.79,;38.66,-28.54,;37.76,-27.3,;36.29,-27.77,;33.77,-34.09,;35.12,-34.84,;36.44,-34.05,;32.45,-34.88,;28.25,-34.92,;27.48,-33.59,;28.25,-32.26,;29.79,-32.26,;27.48,-30.92,;28.26,-29.6,;27.49,-28.26,;25.94,-28.26,;25.17,-26.93,;25.94,-25.6,;27.48,-25.59,;25.17,-24.26,;25.93,-22.93,;27.47,-22.93,;28.25,-24.26,;28.24,-21.59,;29.78,-21.59,;30.55,-20.25,;25.18,-29.61,;25.95,-30.93,;28.26,-36.46,;27.46,-37.76,;28.19,-39.11,;27.4,-40.43,;25.85,-40.4,;25.05,-41.71,;25.79,-43.06,;27.33,-43.1,;24.84,-44.28,;23.3,-44.24,;22.78,-45.69,;23.99,-46.63,;25.27,-45.76,;25.11,-39.04,;23.57,-39,;22.84,-37.65,;25.92,-37.73,;26.71,-34.93,;25.94,-33.59,;25.94,-36.26,;31.33,-36.46,;32.1,-37.8,;31.85,-35.4,)| Show InChI InChI=1S/C54H50N6O18S2/c1-5-75-41(61)27-55-51(71)57-33-17-11-29(12-18-33)45(63)59-53(49(67)68)43(31-15-21-35(37(25-31)73-3)77-47(65)39-9-7-23-79-39)54(50(69)70,44(53)32-16-22-36(38(26-32)74-4)78-48(66)40-10-8-24-80-40)60-46(64)30-13-19-34(20-14-30)58-52(72)56-28-42(62)76-6-2/h7-26,43-44H,5-6,27-28H2,1-4H3,(H,59,63)(H,60,64)(H,67,68)(H,69,70)(H2,55,57,71)(H2,56,58,72)/t43-,44+,53+,54- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50260246
(1,3-bis(4-(tert-butoxycarbonyl)benzamido)-2,4-bis(...)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)C1C(NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)(C(c2ccc(OC(=O)c3cccs3)c(OC)c2)C1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |(.32,-12.51,;1.08,-13.85,;2.62,-13.86,;3.39,-12.53,;4.93,-12.54,;5.69,-13.87,;4.93,-15.19,;3.38,-15.19,;2.61,-16.52,;1.07,-16.52,;.3,-15.18,;.3,-17.85,;-1.23,-18.01,;-1.55,-19.51,;-.22,-20.29,;.93,-19.26,;4.93,-10.99,;4.93,-9.45,;4.92,-7.9,;3.56,-7.14,;2.02,-7.16,;3.56,-5.61,;4.89,-4.84,;4.89,-3.3,;3.55,-2.53,;3.55,-.99,;4.88,-.21,;6.22,-.98,;4.87,1.33,;6.21,2.1,;7.53,2.89,;6.99,.77,;5.43,3.43,;2.22,-3.31,;2.23,-4.85,;6.47,-9.45,;6.46,-7.9,;5.7,-6.57,;6.46,-5.25,;8,-5.24,;8.77,-3.91,;10.31,-3.9,;11.08,-5.24,;11.07,-2.57,;12.6,-2.4,;12.92,-.9,;11.58,-.13,;10.44,-1.16,;8.77,-6.57,;10.31,-6.57,;11.08,-7.91,;8,-7.9,;6.47,-10.99,;6.48,-12.53,;7.83,-13.3,;9.37,-13.29,;7.82,-14.84,;6.48,-15.6,;6.47,-17.14,;7.8,-17.92,;7.8,-19.46,;6.46,-20.22,;5.13,-19.45,;6.45,-21.76,;5.12,-22.53,;3.77,-23.29,;5.88,-23.87,;4.36,-21.19,;9.14,-17.14,;9.15,-15.61,;8.02,-11.01,;8.77,-12.35,;8.8,-9.68,;3.39,-9.44,;2.62,-8.1,;2.61,-10.77,)| Show InChI InChI=1S/C54H52N4O16S2/c1-51(2,3)73-49(67)55-33-19-13-29(14-20-33)43(59)57-53(47(63)64)41(31-17-23-35(37(27-31)69-7)71-45(61)39-11-9-25-75-39)54(48(65)66,58-44(60)30-15-21-34(22-16-30)56-50(68)74-52(4,5)6)42(53)32-18-24-36(38(28-32)70-8)72-46(62)40-12-10-26-76-40/h9-28,41-42H,1-8H3,(H,55,67)(H,56,68)(H,57,59)(H,58,60)(H,63,64)(H,65,66) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393573
(CHEMBL2158423)Show SMILES CCC(=O)Nc1ccc(cc1)C(=O)N[C@@]1([C@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@](NC(=O)c2ccc(NC(=O)CC)cc2)([C@@H]1c1ccc(OC(=O)c2cccs2)c(OC)c1)C(O)=O)C(O)=O |r,wU:15.16,32.35,47.52,14.14,wD:32.70,14.73,(9.59,-16.65,;9.6,-15.11,;10.94,-14.35,;12.27,-15.13,;10.95,-12.81,;9.62,-12.03,;8.28,-12.79,;6.95,-12.01,;6.97,-10.47,;8.3,-9.71,;9.63,-10.48,;5.64,-9.69,;4.31,-10.45,;5.66,-8.15,;4.59,-7.04,;4.59,-5.5,;5.91,-4.71,;5.87,-3.17,;7.18,-2.38,;8.54,-3.12,;9.86,-2.33,;9.83,-.79,;8.48,-.05,;11.08,.11,;12.54,-.36,;13.45,.88,;12.55,2.13,;11.08,1.65,;8.57,-4.67,;9.91,-5.41,;11.23,-4.62,;7.25,-5.46,;3.04,-5.5,;2.28,-4.17,;3.05,-2.83,;4.59,-2.83,;2.27,-1.5,;3.05,-.17,;2.28,1.16,;.74,1.16,;-.04,2.49,;.73,3.83,;-.04,5.16,;2.27,3.83,;3.04,2.5,;-.03,-.18,;.74,-1.51,;3.05,-7.04,;2.25,-8.34,;2.98,-9.68,;2.19,-11.01,;.64,-10.97,;-.16,-12.29,;.58,-13.64,;2.12,-13.68,;-.36,-14.86,;-1.91,-14.81,;-2.43,-16.26,;-1.21,-17.21,;.06,-16.34,;-.09,-9.62,;-1.63,-9.58,;-2.37,-8.23,;.71,-8.31,;1.5,-5.5,;.73,-4.17,;.73,-6.84,;6.12,-7.04,;6.89,-8.37,;6.64,-5.98,)| Show InChI InChI=1S/C50H44N4O14S2/c1-5-39(55)51-31-17-11-27(12-18-31)43(57)53-49(47(61)62)41(29-15-21-33(35(25-29)65-3)67-45(59)37-9-7-23-69-37)50(48(63)64,54-44(58)28-13-19-32(20-14-28)52-40(56)6-2)42(49)30-16-22-34(36(26-30)66-4)68-46(60)38-10-8-24-70-38/h7-26,41-42H,5-6H2,1-4H3,(H,51,55)(H,52,56)(H,53,57)(H,54,58)(H,61,62)(H,63,64)/t41-,42+,49+,50- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393587
(CHEMBL2158408)Show SMILES CCCC(=O)Oc1ccc(cc1OC)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H](c2ccc(OC(=O)CCC)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |r,wU:14.14,48.52,33.35,15.16,wD:48.70,15.73,(11.3,-3.28,;11.27,-1.74,;9.92,-.99,;9.89,.55,;11.21,1.34,;8.55,1.29,;7.23,.5,;7.25,-1.04,;5.93,-1.83,;4.59,-1.08,;4.56,.45,;5.87,1.25,;5.84,2.79,;7.16,3.58,;3.27,-1.87,;3.27,-3.42,;4.34,-4.53,;4.33,-6.07,;2.99,-6.83,;5.66,-6.85,;5.64,-8.39,;6.96,-9.17,;8.31,-8.41,;9.63,-9.19,;9.62,-10.73,;10.95,-11.5,;8.29,-11.49,;8.28,-13.03,;6.94,-13.79,;9.6,-13.8,;8.28,-14.57,;8.31,-6.86,;6.99,-6.08,;1.73,-3.41,;.94,-4.71,;1.66,-6.06,;.88,-7.38,;-.67,-7.35,;-1.47,-8.66,;-3.01,-8.63,;-3.75,-7.28,;-3.81,-9.94,;-3.07,-11.3,;-3.88,-12.61,;-1.41,-5.99,;-2.95,-5.96,;-3.68,-4.6,;-.61,-4.68,;1.73,-1.88,;.96,-.54,;1.73,.79,;3.27,.79,;.96,2.12,;1.73,3.45,;.96,4.78,;-.58,4.78,;-1.35,6.12,;-.58,7.45,;-1.36,8.79,;.96,7.45,;1.72,8.8,;3.26,8.8,;.95,10.13,;2.48,10.13,;-1.35,3.44,;-.57,2.11,;.19,-1.88,;-.58,-.54,;-.58,-3.21,;4.81,-3.41,;5.58,-4.75,;5.33,-2.35,)| Show InChI InChI=1S/C52H60N4O16/c1-11-13-39(57)69-35-25-19-31(27-37(35)67-9)41-51(45(61)62,55-43(59)29-15-21-33(22-16-29)53-47(65)71-49(3,4)5)42(32-20-26-36(38(28-32)68-10)70-40(58)14-12-2)52(41,46(63)64)56-44(60)30-17-23-34(24-18-30)54-48(66)72-50(6,7)8/h15-28,41-42H,11-14H2,1-10H3,(H,53,65)(H,54,66)(H,55,59)(H,56,60)(H,61,62)(H,63,64)/t41-,42+,51+,52- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393586
(CHEMBL2158409)Show SMILES COc1cc(ccc1OC(=O)C(C)C)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H](c2ccc(OC(=O)C(C)C)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |r,wU:14.14,48.52,33.35,15.16,wD:48.70,15.73,(35.61,1.08,;34.29,.28,;34.32,-1.26,;33.01,-2.05,;33.04,-3.59,;34.38,-4.34,;35.7,-3.55,;35.68,-2,;37,-1.21,;38.34,-1.96,;39.66,-1.16,;38.37,-3.5,;37.05,-4.29,;39.72,-4.24,;31.73,-4.38,;31.72,-5.92,;32.79,-7.03,;32.78,-8.57,;31.44,-9.33,;34.11,-9.35,;34.09,-10.89,;35.42,-11.67,;36.76,-10.91,;38.09,-11.69,;38.08,-13.23,;39.4,-14.01,;36.74,-13.99,;36.73,-15.53,;35.39,-16.29,;38.06,-16.31,;36.73,-17.07,;36.76,-9.36,;35.44,-8.59,;30.19,-5.92,;29.39,-7.22,;30.12,-8.56,;29.33,-9.89,;27.78,-9.85,;26.98,-11.17,;25.44,-11.13,;24.7,-9.78,;24.64,-12.45,;25.38,-13.8,;23.1,-12.41,;27.04,-8.5,;25.5,-8.46,;24.77,-7.11,;27.84,-7.19,;30.18,-4.38,;29.41,-3.05,;30.18,-1.71,;31.72,-1.71,;29.41,-.38,;30.18,.95,;29.42,2.28,;27.87,2.28,;27.1,3.61,;27.87,4.95,;27.1,6.28,;29.41,4.95,;30.18,6.29,;31.72,6.29,;29.4,7.63,;30.93,7.63,;27.1,.94,;27.88,-.39,;28.64,-4.38,;27.87,-3.05,;27.87,-5.72,;33.26,-5.92,;34.03,-7.25,;33.78,-4.86,)| Show InChI InChI=1S/C52H60N4O16/c1-27(2)43(59)69-35-23-17-31(25-37(35)67-11)39-51(45(61)62,55-41(57)29-13-19-33(20-14-29)53-47(65)71-49(5,6)7)40(32-18-24-36(38(26-32)68-12)70-44(60)28(3)4)52(39,46(63)64)56-42(58)30-15-21-34(22-16-30)54-48(66)72-50(8,9)10/h13-28,39-40H,1-12H3,(H,53,65)(H,54,66)(H,55,57)(H,56,58)(H,61,62)(H,63,64)/t39-,40+,51+,52- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393604
(CHEMBL2158490)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)C34CC5CC(CC(C5)C3)C4)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)C23CC4CC(CC(C4)C2)C3)cc1)C(O)=O)C(O)=O |r,wU:40.46,16.17,57.66,17.19,wD:57.92,17.95,TLB:66:68:71:75.73.74,THB:36:34:31:37.28.29,36:28:31:35.33.34,73:72:69:75.74.76,73:74:71.72.77:69,76:74:71:77.68.69,76:68:71:75.73.74,33:32:29:35.34.36,33:34:31.32.37:29,(14.15,-10.65,;12.83,-11.44,;11.48,-10.69,;10.16,-11.49,;8.82,-10.74,;8.79,-9.2,;10.1,-8.41,;11.46,-9.15,;12.78,-8.36,;12.75,-6.82,;11.4,-6.07,;14,-5.92,;15.46,-6.39,;16.37,-5.15,;15.47,-3.9,;14,-4.37,;7.51,-11.53,;7.5,-13.07,;8.57,-14.18,;8.56,-15.72,;7.22,-16.48,;9.89,-16.5,;9.87,-18.04,;11.2,-18.82,;12.54,-18.06,;13.87,-18.84,;13.86,-20.38,;15.18,-21.16,;12.51,-21.14,;11.25,-20.47,;10.16,-21.47,;8.41,-21.45,;9.73,-22.28,;10.26,-23.69,;11.89,-23.58,;10.69,-22.78,;13.03,-22.56,;10.9,-21.2,;12.54,-16.51,;11.22,-15.74,;5.97,-13.07,;5.17,-14.36,;5.9,-15.71,;5.11,-17.03,;3.56,-17,;2.76,-18.32,;3.5,-19.67,;5.04,-19.7,;2.55,-20.89,;1.01,-20.84,;.49,-22.29,;1.7,-23.23,;2.98,-22.37,;2.82,-15.65,;1.28,-15.61,;.55,-14.26,;3.62,-14.33,;5.96,-11.53,;5.19,-10.19,;5.96,-8.86,;7.5,-8.86,;5.19,-7.53,;5.96,-6.2,;5.2,-4.87,;3.65,-4.87,;2.88,-3.54,;3.65,-2.2,;2.88,-.87,;5.19,-2.2,;5.16,-3.63,;6.56,-4.14,;7.33,-5.71,;7.47,-4.15,;8.49,-3.04,;7.65,-1.64,;7.48,-3.07,;6.22,-1.09,;5.97,-3.6,;2.88,-6.21,;3.66,-7.54,;4.42,-11.53,;3.65,-10.2,;3.65,-12.86,;9.04,-13.07,;9.81,-14.4,;9.56,-12,)| Show InChI InChI=1S/C66H64N4O14S2/c1-81-49-27-43(11-17-47(49)83-57(73)51-5-3-19-85-51)53-65(61(77)78,69-55(71)41-7-13-45(14-8-41)67-59(75)63-29-35-21-36(30-63)23-37(22-35)31-63)54(44-12-18-48(50(28-44)82-2)84-58(74)52-6-4-20-86-52)66(53,62(79)80)70-56(72)42-9-15-46(16-10-42)68-60(76)64-32-38-24-39(33-64)26-40(25-38)34-64/h3-20,27-28,35-40,53-54H,21-26,29-34H2,1-2H3,(H,67,75)(H,68,76)(H,69,71)(H,70,72)(H,77,78)(H,79,80)/t35?,36?,37?,38?,39?,40?,53-,54+,63?,64?,65+,66- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393599
(CHEMBL2158500)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)CO)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)CO)cc1)C(O)=O)C(O)=O |r,wU:16.17,49.55,32.35,17.19,wD:49.70,17.73,(11.11,-34.3,;9.79,-35.09,;8.44,-34.35,;7.12,-35.14,;5.78,-34.39,;5.75,-32.85,;7.06,-32.06,;8.42,-32.8,;9.74,-32.01,;9.71,-30.47,;8.36,-29.73,;10.96,-29.57,;12.42,-30.04,;13.33,-28.8,;12.42,-27.55,;10.96,-28.03,;4.46,-35.18,;4.46,-36.72,;5.53,-37.83,;5.52,-39.37,;4.18,-40.13,;6.85,-40.15,;6.83,-41.69,;8.15,-42.47,;9.5,-41.71,;10.82,-42.49,;10.81,-44.03,;12.14,-44.81,;9.48,-44.79,;8.15,-44.01,;9.5,-40.16,;8.18,-39.39,;2.92,-36.72,;2.13,-38.02,;2.85,-39.36,;2.07,-40.69,;.52,-40.65,;-.28,-41.97,;.46,-43.32,;2,-43.36,;-.49,-44.54,;-2.03,-44.49,;-2.56,-45.94,;-1.34,-46.89,;-.06,-46.02,;-.22,-39.3,;-1.76,-39.26,;-2.49,-37.91,;.58,-37.99,;2.92,-35.18,;2.15,-33.85,;2.92,-32.51,;4.46,-32.51,;2.15,-31.18,;2.92,-29.85,;2.15,-28.52,;.61,-28.52,;-.16,-27.19,;.61,-25.85,;-.17,-24.52,;2.14,-25.85,;2.91,-27.19,;-.16,-29.86,;.62,-31.19,;1.38,-35.18,;.61,-33.85,;.61,-36.52,;6,-36.72,;6.77,-38.05,;6.52,-35.66,)| Show InChI InChI=1S/C48H40N4O16S2/c1-65-33-21-27(11-17-31(33)67-43(59)35-5-3-19-69-35)39-47(45(61)62,51-41(57)25-7-13-29(14-8-25)49-37(55)23-53)40(28-12-18-32(34(22-28)66-2)68-44(60)36-6-4-20-70-36)48(39,46(63)64)52-42(58)26-9-15-30(16-10-26)50-38(56)24-54/h3-22,39-40,53-54H,23-24H2,1-2H3,(H,49,55)(H,50,56)(H,51,57)(H,52,58)(H,61,62)(H,63,64)/t39-,40+,47+,48- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393570
(CHEMBL2158492)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)CCl)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)CCl)cc1)C(O)=O)C(O)=O |r,wU:16.17,49.55,32.35,17.19,wD:49.70,17.73,(8.11,-32.7,;6.79,-33.49,;5.44,-32.74,;4.12,-33.54,;2.78,-32.79,;2.74,-31.25,;4.06,-30.46,;5.41,-31.2,;6.73,-30.41,;6.71,-28.87,;5.36,-28.12,;7.95,-27.97,;9.42,-28.44,;10.33,-27.2,;9.42,-25.95,;7.96,-26.42,;1.46,-33.58,;1.46,-35.12,;2.53,-36.23,;2.52,-37.77,;1.18,-38.53,;3.85,-38.55,;3.83,-40.09,;5.15,-40.87,;6.49,-40.11,;7.82,-40.89,;7.81,-42.43,;9.14,-43.21,;6.47,-43.19,;5.15,-42.41,;6.5,-38.56,;5.17,-37.79,;-.08,-35.12,;-.87,-36.41,;-.15,-37.76,;-.94,-39.08,;-2.48,-39.05,;-3.28,-40.37,;-2.55,-41.72,;-1.01,-41.75,;-3.49,-42.94,;-5.04,-42.89,;-5.56,-44.34,;-4.34,-45.28,;-3.07,-44.42,;-3.22,-37.7,;-4.76,-37.66,;-5.5,-36.31,;-2.42,-36.38,;-.08,-33.58,;-.85,-32.24,;-.08,-30.91,;1.46,-30.91,;-.85,-29.58,;-.08,-28.25,;-.85,-26.92,;-2.39,-26.92,;-3.16,-25.59,;-2.39,-24.25,;-3.17,-22.92,;-.85,-24.25,;-.08,-25.58,;-3.16,-28.26,;-2.38,-29.59,;-1.63,-33.58,;-2.4,-32.25,;-2.39,-34.91,;2.99,-35.12,;3.77,-36.45,;3.51,-34.05,)| Show InChI InChI=1S/C48H38Cl2N4O14S2/c1-65-33-21-27(11-17-31(33)67-43(59)35-5-3-19-69-35)39-47(45(61)62,53-41(57)25-7-13-29(14-8-25)51-37(55)23-49)40(28-12-18-32(34(22-28)66-2)68-44(60)36-6-4-20-70-36)48(39,46(63)64)54-42(58)26-9-15-30(16-10-26)52-38(56)24-50/h3-22,39-40H,23-24H2,1-2H3,(H,51,55)(H,52,56)(H,53,57)(H,54,58)(H,61,62)(H,63,64)/t39-,40+,47+,48- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393581
(CHEMBL2158316)Show SMILES COc1cc(ccc1OC(=O)C1CCC1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)C(C)C)cc2)([C@@H](c2ccc(OC(=O)C3CCC3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)C(C)C)cc1)C(O)=O)C(O)=O |r,wU:15.16,48.54,32.35,16.18,wD:48.70,16.73,(8.33,2.38,;7.01,1.58,;7.04,.04,;5.73,-.75,;5.77,-2.29,;7.11,-3.04,;8.43,-2.25,;8.4,-.71,;9.72,.09,;11.07,-.66,;12.39,.14,;11.1,-2.19,;10.03,-3.3,;11.13,-4.37,;12.2,-3.26,;4.45,-3.08,;4.45,-4.62,;5.52,-5.73,;5.5,-7.27,;4.17,-8.03,;6.83,-8.05,;6.81,-9.59,;8.14,-10.37,;9.48,-9.61,;10.81,-10.39,;10.8,-11.93,;12.13,-12.71,;9.46,-12.69,;8.13,-11.91,;9.45,-14.23,;9.49,-8.06,;8.16,-7.29,;2.91,-4.62,;2.11,-5.92,;2.84,-7.27,;2.05,-8.59,;.5,-8.55,;-.3,-9.87,;-1.84,-9.83,;-2.58,-8.48,;-2.63,-11.15,;-4.13,-11.51,;-3.77,-13.01,;-2.27,-12.65,;-.23,-7.2,;-1.77,-7.16,;-2.51,-5.81,;.57,-5.89,;2.9,-3.08,;2.14,-1.75,;2.91,-.41,;4.45,-.41,;2.13,.92,;2.91,2.25,;2.14,3.58,;.6,3.58,;-.18,4.91,;.59,6.25,;-.18,7.59,;2.13,6.25,;2.9,4.92,;2.9,7.6,;-.17,2.24,;.6,.91,;1.36,-3.08,;.59,-1.75,;.59,-4.42,;5.98,-4.62,;6.75,-5.95,;6.5,-3.56,)| Show InChI InChI=1S/C52H56N4O14/c1-27(2)43(57)53-35-19-13-29(14-20-35)45(59)55-51(49(63)64)41(33-17-23-37(39(25-33)67-5)69-47(61)31-9-7-10-31)52(50(65)66,56-46(60)30-15-21-36(22-16-30)54-44(58)28(3)4)42(51)34-18-24-38(40(26-34)68-6)70-48(62)32-11-8-12-32/h13-28,31-32,41-42H,7-12H2,1-6H3,(H,53,57)(H,54,58)(H,55,59)(H,56,60)(H,63,64)(H,65,66)/t41-,42+,51+,52- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393600
(CHEMBL2158499)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)C(C)N)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)C(C)N)cc1)C(O)=O)C(O)=O |r,wU:33.36,17.19,16.17,50.56,wD:17.75,50.72,(35.34,-8.22,;34.02,-9.01,;32.68,-8.26,;31.36,-9.05,;30.02,-8.3,;29.98,-6.77,;31.3,-5.97,;32.65,-6.72,;33.97,-5.92,;33.94,-4.38,;32.6,-3.64,;35.19,-3.48,;36.66,-3.96,;37.56,-2.71,;36.66,-1.47,;35.19,-1.94,;28.7,-9.09,;28.7,-10.63,;29.77,-11.75,;29.76,-13.29,;28.42,-14.05,;31.08,-14.07,;31.06,-15.6,;32.39,-16.38,;33.73,-15.62,;35.06,-16.4,;36.4,-15.64,;36.41,-14.1,;37.73,-16.42,;37.72,-17.96,;39.07,-15.66,;33.74,-14.08,;32.41,-13.3,;27.16,-10.63,;26.37,-11.93,;27.09,-13.28,;26.3,-14.6,;24.75,-14.57,;23.95,-15.88,;24.69,-17.23,;26.23,-17.27,;23.75,-18.45,;22.2,-18.41,;21.68,-19.86,;22.9,-20.8,;24.17,-19.93,;24.02,-13.21,;22.48,-13.17,;21.74,-11.82,;24.82,-11.9,;27.16,-9.09,;26.39,-7.76,;27.16,-6.43,;28.7,-6.43,;26.39,-5.09,;27.16,-3.77,;26.39,-2.43,;24.85,-2.43,;24.08,-1.1,;24.84,.23,;26.38,.24,;24.07,1.57,;22.53,1.56,;24.84,2.9,;24.08,-3.78,;24.85,-5.1,;25.61,-9.1,;24.84,-7.76,;24.84,-10.43,;30.23,-10.63,;31,-11.97,;30.75,-9.57,)| Show InChI InChI=1S/C50H46N6O14S2/c1-25(51)41(57)53-31-15-9-27(10-16-31)43(59)55-49(47(63)64)39(29-13-19-33(35(23-29)67-3)69-45(61)37-7-5-21-71-37)50(48(65)66,56-44(60)28-11-17-32(18-12-28)54-42(58)26(2)52)40(49)30-14-20-34(36(24-30)68-4)70-46(62)38-8-6-22-72-38/h5-26,39-40H,51-52H2,1-4H3,(H,53,57)(H,54,58)(H,55,59)(H,56,60)(H,63,64)(H,65,66)/t25?,26?,39-,40+,49+,50- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.62E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393583
(CHEMBL2158313)Show SMILES COc1cc(ccc1OC(=O)c1ccc(C)s1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H](c2ccc(OC(=O)c3ccc(C)s3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |r,wU:36.39,18.20,17.18,54.60,wD:18.81,54.78,(-.94,-8.57,;-.2,-9.92,;1.34,-9.96,;2.14,-8.65,;3.69,-8.68,;4.41,-10.03,;3.62,-11.35,;2.07,-11.32,;1.27,-12.63,;-.27,-12.59,;-1.01,-11.24,;-1.15,-13.86,;-.64,-15.32,;-1.87,-16.25,;-3.13,-15.37,;-4.59,-15.87,;-2.68,-13.9,;4.48,-7.38,;4.48,-5.84,;3.71,-4.51,;4.48,-3.18,;6.02,-3.17,;3.71,-1.84,;4.48,-.51,;3.71,.82,;2.17,.82,;1.4,2.15,;2.16,3.49,;1.39,4.82,;3.7,3.49,;4.47,4.82,;6.01,4.83,;3.7,6.16,;5.23,6.17,;1.4,-.53,;2.17,-1.85,;6.02,-5.84,;7.34,-5.05,;8.68,-5.8,;10,-5.01,;9.97,-3.47,;11.29,-2.67,;12.64,-3.42,;13.96,-2.62,;12.67,-4.96,;11.44,-5.89,;11.94,-7.35,;13.48,-7.32,;14.41,-8.55,;13.93,-5.85,;8.62,-2.72,;8.58,-1.18,;9.9,-.38,;7.3,-3.52,;6.02,-7.38,;7.09,-8.5,;7.08,-10.04,;5.74,-10.79,;8.4,-10.82,;8.38,-12.35,;9.71,-13.13,;11.05,-12.37,;12.38,-13.15,;12.37,-14.69,;13.7,-15.47,;11.03,-15.45,;11.02,-16.99,;9.68,-17.75,;12.35,-17.77,;11.03,-18.54,;11.06,-10.82,;9.73,-10.05,;7.55,-7.38,;8.32,-8.71,;8.07,-6.32,;2.93,-5.84,;2.16,-4.51,;2.16,-7.18,)| Show InChI InChI=1S/C56H56N4O16S2/c1-29-11-25-41(77-29)47(63)73-37-23-17-33(27-39(37)71-9)43-55(49(65)66,59-45(61)31-13-19-35(20-14-31)57-51(69)75-53(3,4)5)44(34-18-24-38(40(28-34)72-10)74-48(64)42-26-12-30(2)78-42)56(43,50(67)68)60-46(62)32-15-21-36(22-16-32)58-52(70)76-54(6,7)8/h11-28,43-44H,1-10H3,(H,57,69)(H,58,70)(H,59,61)(H,60,62)(H,65,66)(H,67,68)/t43-,44+,55+,56- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393596
(CHEMBL2158395)Show SMILES CC(C)(C)OC(=O)Nc1ccc(cc1)C(=O)N[C@@]1([C@H](c2cccc(OCc3ccccc3)c2)[C@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H]1c1cccc(OCc2ccccc2)c1)C(O)=O)C(O)=O |r,wU:18.19,33.36,51.56,17.17,wD:33.72,17.75,(7.25,-16.86,;8.59,-16.1,;9.92,-16.88,;8.59,-17.64,;8.6,-14.56,;9.94,-13.8,;11.26,-14.58,;9.95,-12.26,;8.62,-11.48,;7.28,-12.24,;5.95,-11.46,;5.97,-9.92,;7.3,-9.16,;8.62,-9.93,;4.64,-9.14,;3.3,-9.9,;4.65,-7.6,;3.58,-6.49,;3.59,-4.95,;4.9,-4.16,;4.87,-2.62,;6.18,-1.83,;7.54,-2.57,;7.56,-4.11,;8.91,-4.86,;10.23,-4.07,;11.58,-4.82,;11.59,-6.36,;12.94,-7.1,;14.26,-6.31,;14.23,-4.76,;12.88,-4.02,;6.24,-4.91,;2.04,-4.95,;1.27,-3.61,;2.04,-2.28,;3.58,-2.28,;1.27,-.95,;2.04,.38,;1.28,1.71,;-.27,1.71,;-1.04,3.04,;-.27,4.38,;-1.04,5.71,;1.27,4.38,;2.04,5.72,;3.58,5.72,;1.26,7.05,;2.79,7.06,;-1.04,.37,;-.26,-.96,;2.05,-6.49,;1.25,-7.78,;1.98,-9.13,;1.19,-10.45,;-.36,-10.42,;-1.1,-9.07,;-2.64,-9.03,;-3.37,-7.68,;-4.91,-7.64,;-5.64,-6.29,;-7.18,-6.25,;-7.98,-7.56,;-7.24,-8.92,;-5.7,-8.95,;-.3,-7.75,;.5,-4.95,;-.27,-3.62,;-.27,-6.28,;5.12,-6.49,;5.89,-7.82,;5.64,-5.42,)| Show InChI InChI=1S/C56H56N4O12/c1-53(2,3)71-51(67)57-41-27-23-37(24-28-41)47(61)59-55(49(63)64)45(39-19-13-21-43(31-39)69-33-35-15-9-7-10-16-35)56(50(65)66,46(55)40-20-14-22-44(32-40)70-34-36-17-11-8-12-18-36)60-48(62)38-25-29-42(30-26-38)58-52(68)72-54(4,5)6/h7-32,45-46H,33-34H2,1-6H3,(H,57,67)(H,58,68)(H,59,61)(H,60,62)(H,63,64)(H,65,66)/t45-,46+,55+,56- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393582
(CHEMBL2158315)Show SMILES COc1cc(ccc1OC(=O)C1CCCCC1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H](c2ccc(OC(=O)C3CCCCC3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |r,wU:36.39,18.20,17.18,54.60,wD:18.81,54.78,(.45,-38.27,;1.18,-39.62,;2.72,-39.66,;3.52,-38.34,;5.07,-38.37,;5.79,-39.72,;5.01,-41.04,;3.46,-41.01,;2.66,-42.33,;1.12,-42.29,;.38,-40.94,;.32,-43.61,;-1.22,-43.57,;-2.02,-44.88,;-1.29,-46.23,;.25,-46.27,;1.06,-44.96,;5.86,-37.08,;5.86,-35.54,;5.09,-34.2,;5.86,-32.87,;7.4,-32.87,;5.09,-31.54,;5.86,-30.21,;5.09,-28.88,;3.55,-28.88,;2.78,-27.55,;3.55,-26.21,;2.77,-24.88,;5.09,-26.21,;5.85,-24.87,;7.39,-24.87,;5.08,-23.54,;6.61,-23.53,;2.78,-30.22,;3.56,-31.55,;7.4,-35.54,;8.72,-34.75,;10.06,-35.5,;11.38,-34.7,;11.36,-33.16,;12.68,-32.37,;14.02,-33.11,;15.34,-32.32,;14.05,-34.65,;12.73,-35.44,;12.75,-36.97,;14.1,-37.73,;15.42,-36.93,;15.4,-35.39,;10,-32.42,;9.97,-30.88,;11.29,-30.08,;8.69,-33.21,;7.4,-37.08,;8.47,-38.19,;8.46,-39.73,;7.12,-40.49,;9.79,-40.51,;9.77,-42.05,;11.09,-42.83,;12.44,-42.07,;13.76,-42.85,;13.75,-44.39,;15.08,-45.17,;12.42,-45.15,;12.41,-46.69,;11.07,-47.45,;13.73,-47.47,;12.41,-48.23,;12.44,-40.52,;11.12,-39.75,;8.94,-37.08,;9.71,-38.41,;9.46,-36.01,;4.32,-35.54,;3.55,-34.21,;3.55,-36.87,)| Show InChI InChI=1S/C58H68N4O16/c1-55(2,3)77-53(71)59-39-25-19-33(20-26-39)47(63)61-57(51(67)68)45(37-23-29-41(43(31-37)73-7)75-49(65)35-15-11-9-12-16-35)58(52(69)70,62-48(64)34-21-27-40(28-22-34)60-54(72)78-56(4,5)6)46(57)38-24-30-42(44(32-38)74-8)76-50(66)36-17-13-10-14-18-36/h19-32,35-36,45-46H,9-18H2,1-8H3,(H,59,71)(H,60,72)(H,61,63)(H,62,64)(H,67,68)(H,69,70)/t45-,46+,57+,58- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393579
(CHEMBL2158415)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1C[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O |r| Show InChI InChI=1S/C28H28N2O8S/c1-27(2,3)38-26(35)29-18-10-7-16(8-11-18)23(31)30-28(25(33)34)15-19(28)17-9-12-20(21(14-17)36-4)37-24(32)22-6-5-13-39-22/h5-14,19H,15H2,1-4H3,(H,29,35)(H,30,31)(H,33,34)/t19-,28-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393578
(CHEMBL2158416)Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(N)=O)C(N)=O |r,wU:35.38,17.19,16.17,52.58,wD:17.79,52.76,(16.51,-8.98,;17.24,-10.33,;18.78,-10.37,;19.58,-9.06,;21.13,-9.09,;21.86,-10.44,;21.07,-11.76,;19.52,-11.73,;18.72,-13.04,;19.46,-14.39,;21,-14.43,;18.51,-15.61,;16.97,-15.57,;16.45,-17.02,;17.66,-17.96,;18.94,-17.09,;21.93,-7.79,;21.92,-6.26,;21.15,-4.92,;21.92,-3.59,;23.46,-3.59,;21.15,-2.25,;21.92,-.93,;21.16,.41,;19.61,.41,;18.84,1.74,;19.61,3.07,;18.84,4.41,;21.15,3.08,;21.92,4.41,;23.46,4.41,;21.14,5.74,;22.67,5.76,;18.84,-.94,;19.62,-2.26,;23.47,-6.25,;24.78,-5.46,;24.75,-3.93,;26.06,-3.13,;27.42,-3.88,;28.74,-3.09,;28.71,-1.55,;27.36,-.8,;29.96,-.64,;31.42,-1.12,;32.33,.13,;31.43,1.37,;29.96,.9,;27.44,-5.42,;28.79,-6.17,;30.11,-5.38,;26.12,-6.21,;23.46,-7.79,;24.53,-8.91,;24.52,-10.45,;23.18,-11.21,;25.85,-11.23,;25.83,-12.76,;27.16,-13.54,;28.5,-12.79,;29.83,-13.56,;29.82,-15.1,;31.14,-15.88,;28.48,-15.87,;28.47,-17.41,;27.13,-18.17,;29.8,-18.18,;28.47,-18.95,;28.5,-11.24,;27.18,-10.46,;25,-7.79,;25.77,-9.13,;25.52,-6.73,;20.38,-6.26,;19.61,-4.92,;19.61,-7.59,)| Show InChI InChI=1S/C54H54N6O14S2/c1-51(2,3)73-49(67)57-33-19-13-29(14-20-33)43(61)59-53(47(55)65)41(31-17-23-35(37(27-31)69-7)71-45(63)39-11-9-25-75-39)54(48(56)66,60-44(62)30-15-21-34(22-16-30)58-50(68)74-52(4,5)6)42(53)32-18-24-36(38(28-32)70-8)72-46(64)40-12-10-26-76-40/h9-28,41-42H,1-8H3,(H2,55,65)(H2,56,66)(H,57,67)(H,58,68)(H,59,61)(H,60,62)/t41-,42+,53+,54- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393577
(CHEMBL2158417)Show SMILES COC(=O)[C@@]1(NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)[C@H](c2ccc(OC(=O)c3cccs3)c(OC)c2)[C@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H]1c1ccc(OC(=O)c2cccs2)c(OC)c1)C(=O)OC |r,wU:57.62,4.4,22.23,39.42,wD:4.3,39.80,(1.51,-33.71,;3.05,-33.71,;3.82,-35.04,;3.05,-36.38,;5.36,-35.04,;4.59,-33.71,;5.36,-32.37,;6.9,-32.37,;4.59,-31.04,;5.37,-29.71,;4.6,-28.38,;3.05,-28.38,;2.28,-27.05,;3.05,-25.71,;2.28,-24.38,;4.59,-25.71,;5.36,-24.37,;6.9,-24.37,;4.58,-23.04,;6.11,-23.03,;2.29,-29.72,;3.06,-31.05,;5.37,-36.58,;4.57,-37.88,;5.3,-39.22,;4.51,-40.55,;2.96,-40.51,;2.16,-41.83,;2.9,-43.18,;4.44,-43.22,;1.95,-44.4,;.41,-44.35,;-.11,-45.8,;1.1,-46.75,;2.38,-45.88,;2.22,-39.16,;.68,-39.12,;-.05,-37.77,;3.03,-37.85,;6.91,-36.58,;7.97,-37.69,;7.96,-39.23,;6.62,-39.99,;9.29,-40.01,;9.27,-41.55,;10.6,-42.33,;11.94,-41.57,;13.27,-42.35,;13.26,-43.89,;14.59,-44.67,;11.92,-44.65,;11.91,-46.19,;10.57,-46.95,;13.24,-46.97,;11.91,-47.73,;11.95,-40.02,;10.62,-39.25,;6.91,-35.04,;8.23,-34.25,;8.19,-32.71,;9.5,-31.92,;10.86,-32.66,;12.18,-31.87,;12.15,-30.33,;10.8,-29.59,;13.4,-29.43,;14.86,-29.9,;15.77,-28.66,;14.87,-27.41,;13.4,-27.89,;10.88,-34.21,;12.23,-34.95,;13.55,-34.16,;9.56,-35,;8.44,-36.58,;8.96,-35.52,;9.21,-37.91,;10.75,-37.91,)| Show InChI InChI=1S/C56H56N4O16S2/c1-53(2,3)75-51(67)57-35-21-15-31(16-22-35)45(61)59-55(49(65)71-9)43(33-19-25-37(39(29-33)69-7)73-47(63)41-13-11-27-77-41)56(50(66)72-10,60-46(62)32-17-23-36(24-18-32)58-52(68)76-54(4,5)6)44(55)34-20-26-38(40(30-34)70-8)74-48(64)42-14-12-28-78-42/h11-30,43-44H,1-10H3,(H,57,67)(H,58,68)(H,59,61)(H,60,62)/t43-,44+,55+,56- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393593
(CHEMBL2158400)Show SMILES COc1ccc(cc1OCCCc1ccccc1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H](c2ccc(OCCCc3ccccc3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C62H68N4O14/c1-59(2,3)79-57(73)63-45-29-23-41(24-30-45)53(67)65-61(55(69)70)51(43-28-34-48(49(37-43)76-8)77-35-15-21-39-17-11-9-12-18-39)62(56(71)72,66-54(68)42-25-31-46(32-26-42)64-58(74)80-60(4,5)6)52(61)44-27-33-47(75-7)50(38-44)78-36-16-22-40-19-13-10-14-20-40/h9-14,17-20,23-34,37-38,51-52H,15-16,21-22,35-36H2,1-8H3,(H,63,73)(H,64,74)(H,65,67)(H,66,68)(H,69,70)(H,71,72)/t51-,52+,61+,62- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393565
(CHEMBL2158391)Show SMILES COc1cccc(c1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H](c2cccc(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |r,wU:8.8,36.40,27.29,9.10,wD:36.58,9.61,(8.25,-4.56,;6.93,-5.35,;5.58,-4.6,;5.55,-3.06,;4.2,-2.32,;2.88,-3.11,;2.92,-4.65,;4.26,-5.4,;1.6,-5.44,;1.6,-6.98,;2.67,-8.09,;2.66,-9.63,;1.32,-10.39,;3.99,-10.41,;3.97,-11.95,;5.29,-12.73,;6.63,-11.97,;7.96,-12.75,;7.95,-14.29,;9.28,-15.07,;6.61,-15.05,;6.6,-16.59,;5.27,-17.35,;7.93,-17.37,;6.61,-18.13,;6.64,-10.42,;5.31,-9.65,;.06,-6.98,;-.73,-8.27,;-.01,-9.62,;-.8,-10.94,;-2.34,-10.91,;-3.08,-9.56,;-4.62,-9.52,;-5.36,-8.17,;-2.28,-8.24,;.06,-5.44,;-.71,-4.1,;.06,-2.77,;1.6,-2.77,;-.71,-1.44,;.06,-.11,;-.71,1.22,;-2.25,1.22,;-3.02,2.55,;-2.25,3.89,;-3.03,5.22,;-.71,3.89,;.05,5.23,;1.59,5.23,;-.72,6.56,;.81,6.57,;-3.02,-.12,;-2.24,-1.45,;-1.49,-5.44,;-2.26,-4.11,;-2.25,-6.77,;3.13,-6.98,;3.91,-8.31,;3.65,-5.91,)| Show InChI InChI=1S/C44H48N4O12/c1-41(2,3)59-39(55)45-29-19-15-25(16-20-29)35(49)47-43(37(51)52)33(27-11-9-13-31(23-27)57-7)44(38(53)54,34(43)28-12-10-14-32(24-28)58-8)48-36(50)26-17-21-30(22-18-26)46-40(56)60-42(4,5)6/h9-24,33-34H,1-8H3,(H,45,55)(H,46,56)(H,47,49)(H,48,50)(H,51,52)(H,53,54)/t33-,34+,43+,44- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393594
(CHEMBL2158399)Show SMILES COc1cc(ccc1OCc1ccc(F)cc1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H](c2ccc(OCc3ccc(F)cc3)c(OC)c2)[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |r,wU:36.39,18.20,17.18,54.60,wD:18.81,54.78,(-1.48,-7.62,;-.75,-8.97,;.79,-9.01,;1.59,-7.7,;3.14,-7.73,;3.87,-9.08,;3.08,-10.4,;1.53,-10.37,;.73,-11.68,;-.81,-11.65,;-1.61,-12.96,;-3.15,-12.92,;-3.95,-14.24,;-3.21,-15.59,;-4.01,-16.91,;-1.66,-15.62,;-.87,-14.31,;3.94,-6.43,;3.93,-4.89,;3.16,-3.56,;3.93,-2.23,;5.47,-2.23,;3.16,-.89,;3.93,.43,;3.17,1.77,;1.62,1.77,;.85,3.1,;1.62,4.43,;.85,5.77,;3.16,4.44,;3.93,5.77,;5.47,5.77,;3.15,7.1,;4.68,7.12,;.85,.42,;1.63,-.9,;5.48,-4.89,;6.79,-4.1,;6.76,-2.57,;8.07,-1.77,;9.43,-2.52,;10.75,-1.72,;10.72,-.18,;12.04,.61,;13.38,-.14,;14.7,.66,;14.67,2.2,;15.99,2.99,;13.32,2.94,;12,2.14,;9.45,-4.06,;10.8,-4.81,;12.12,-4.02,;8.13,-4.85,;5.47,-6.43,;6.54,-7.55,;6.53,-9.09,;5.19,-9.85,;7.86,-9.87,;7.84,-11.4,;9.17,-12.18,;10.51,-11.42,;11.84,-12.2,;11.83,-13.74,;13.15,-14.52,;10.49,-14.5,;10.48,-16.04,;9.14,-16.81,;11.81,-16.82,;10.48,-17.59,;10.51,-9.88,;9.19,-9.1,;7.01,-6.43,;7.78,-7.77,;7.53,-5.37,;2.39,-4.9,;1.62,-3.56,;1.62,-6.23,)| Show InChI InChI=1S/C58H58F2N4O14/c1-55(2,3)77-53(71)61-41-23-13-35(14-24-41)49(65)63-57(51(67)68)47(37-17-27-43(45(29-37)73-7)75-31-33-9-19-39(59)20-10-33)58(52(69)70,64-50(66)36-15-25-42(26-16-36)62-54(72)78-56(4,5)6)48(57)38-18-28-44(46(30-38)74-8)76-32-34-11-21-40(60)22-12-34/h9-30,47-48H,31-32H2,1-8H3,(H,61,71)(H,62,72)(H,63,65)(H,64,66)(H,67,68)(H,69,70)/t47-,48+,57+,58- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Rattus norvegicus) | BDBM50393597
(CHEMBL2158394)Show SMILES CCCOc1ccc(cc1)[C@H]1[C@@](NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)([C@@H](c2ccc(OCCC)cc2)[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O |r,wU:10.10,40.44,29.31,11.12,wD:40.62,11.65,(34.55,-25.37,;34.58,-26.91,;33.26,-27.7,;33.29,-29.24,;31.97,-30.04,;31.99,-31.58,;30.67,-32.37,;29.33,-31.62,;29.3,-30.08,;30.61,-29.29,;28.02,-32.41,;28.01,-33.95,;29.08,-35.06,;29.07,-36.6,;27.73,-37.36,;30.4,-37.38,;30.38,-38.92,;31.71,-39.7,;33.05,-38.94,;34.38,-39.72,;34.37,-41.26,;35.69,-42.04,;33.03,-42.02,;33.02,-43.56,;31.68,-44.32,;34.35,-44.34,;33.02,-45.1,;33.05,-37.39,;31.73,-36.62,;26.48,-33.95,;25.68,-35.25,;24.13,-35.22,;23.33,-36.53,;24.07,-37.88,;23.27,-39.2,;21.73,-39.16,;20.93,-40.48,;19.39,-40.44,;25.62,-37.92,;26.41,-36.6,;26.47,-32.41,;25.7,-31.08,;26.47,-29.74,;28.01,-29.74,;25.7,-28.41,;26.47,-27.08,;25.71,-25.75,;24.16,-25.75,;23.39,-24.42,;24.16,-23.08,;23.39,-21.75,;25.7,-23.08,;26.47,-21.75,;28.01,-21.74,;25.69,-20.41,;27.22,-20.4,;23.39,-27.09,;24.17,-28.42,;24.93,-32.41,;24.16,-31.08,;24.16,-33.75,;29.55,-33.95,;30.32,-35.28,;30.07,-32.89,)| Show InChI InChI=1S/C48H56N4O12/c1-9-27-61-35-23-15-29(16-24-35)37-47(41(55)56,51-39(53)31-11-19-33(20-12-31)49-43(59)63-45(3,4)5)38(30-17-25-36(26-18-30)62-28-10-2)48(37,42(57)58)52-40(54)32-13-21-34(22-14-32)50-44(60)64-46(6,7)8/h11-26,37-38H,9-10,27-28H2,1-8H3,(H,49,59)(H,50,60)(H,51,53)(H,52,54)(H,55,56)(H,57,58)/t37-,38+,47+,48- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The National Center for Drug Screening
Curated by ChEMBL
| Assay Description
Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cells |
J Med Chem 55: 250-67 (2012)
Article DOI: 10.1021/jm201150j
BindingDB Entry DOI: 10.7270/Q2M046JC |
More data for this
Ligand-Target Pair | |
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