BindingDB PrimarySearch

Found 3 hits of ec50 for UniProtKB: P19332
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Microtubule-associated protein tau (Rattus norvegicus)	BDBM50487729 (CHEMBL454948) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of microtubule polymerisation in Rattus norvegicus (rat) A10 cells				Citation and Details Article DOI: 10.1007/s00044-010-9334-1 BindingDB Entry DOI: 10.7270/Q2QN69N6
TBA					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Rattus norvegicus)	BDBM50487730 (CHEMBL508222) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of microtubule polymerisation in Rattus norvegicus (rat) A10 cells				Citation and Details Article DOI: 10.1007/s00044-010-9334-1 BindingDB Entry DOI: 10.7270/Q2QN69N6
TBA					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Rattus norvegicus)	BDBM50340902 ((4-amino-2-(pyridin-3-ylamino)thiazol-5-yl)(2-fluo...) Show SMILES Nc1nc(Nc2cccnc2)sc1C(=O)c1ccccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of tau protein phosphorylation at Ser396 in rat brain cells at 0.5 to 50 uM after 4 hrs				Bioorg Med Chem Lett 21: 2098-101 (2011) Article DOI: 10.1016/j.bmcl.2011.01.140 BindingDB Entry DOI: 10.7270/Q2GT5NG8
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair