Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin receptor type B (Mus musculus) | BDBM50304497 (2-(5-{[4-(Benzo[1,3]dioxol-5-yl)-2-hydroxy-2-(4-me...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital M£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from endothelin B receptor in DBA mouse microsomes | Bioorg Med Chem 17: 7197-208 (2009) Article DOI: 10.1016/j.bmc.2009.08.058 BindingDB Entry DOI: 10.7270/Q27S7NVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Mus musculus) | BDBM50336697 (3-Benzo[1,3]dioxol-5-yl-4-[3-(2-{2-[2-(2-{4-[4-(2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital Mu£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma counting | J Med Chem 54: 939-48 (2011) Article DOI: 10.1021/jm101110w BindingDB Entry DOI: 10.7270/Q2V69JW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Mus musculus) | BDBM50304499 (3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-[4-(2-bromoeth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital M£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from endothelin B receptor in DBA mouse microsomes | Bioorg Med Chem 17: 7197-208 (2009) Article DOI: 10.1016/j.bmc.2009.08.058 BindingDB Entry DOI: 10.7270/Q27S7NVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Mus musculus) | BDBM50304495 (2-{4-[4-(Benzo[1,3]dioxol-5-yl)-2-hydroxy-5-oxo-3-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 96 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital M£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from endothelin B receptor in DBA mouse microsomes | Bioorg Med Chem 17: 7197-208 (2009) Article DOI: 10.1016/j.bmc.2009.08.058 BindingDB Entry DOI: 10.7270/Q27S7NVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Mus musculus) | BDBM50304498 (3-Benzo[1,3]dioxol-5-yl-5-[4-(2-fluoroethoxy)pheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital M£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from endothelin B receptor in DBA mouse microsomes | Bioorg Med Chem 17: 7197-208 (2009) Article DOI: 10.1016/j.bmc.2009.08.058 BindingDB Entry DOI: 10.7270/Q27S7NVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Mus musculus) | BDBM50304494 (3-Benzo[1,3]dioxol-5-yl-4-[3-(2-bromoethoxy)-4,5-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital M£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from endothelin B receptor in DBA mouse microsomes | Bioorg Med Chem 17: 7197-208 (2009) Article DOI: 10.1016/j.bmc.2009.08.058 BindingDB Entry DOI: 10.7270/Q27S7NVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Mus musculus) | BDBM50304496 (3-Benzo[1,3]dioxol-5-yl-4-[3-(2-fluoroethoxy)-4,5-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital M£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from endothelin B receptor in DBA mouse microsomes | Bioorg Med Chem 17: 7197-208 (2009) Article DOI: 10.1016/j.bmc.2009.08.058 BindingDB Entry DOI: 10.7270/Q27S7NVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Mus musculus) | BDBM50304496 (3-Benzo[1,3]dioxol-5-yl-4-[3-(2-fluoroethoxy)-4,5-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital Mu£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma counting | J Med Chem 54: 939-48 (2011) Article DOI: 10.1021/jm101110w BindingDB Entry DOI: 10.7270/Q2V69JW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Mus musculus) | BDBM50336699 (CHEMBL1672884 | N-[1-(2-{2-[2-(2-{5-[4-Benzo[1,3]d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 288 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital Mu£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma counting | J Med Chem 54: 939-48 (2011) Article DOI: 10.1021/jm101110w BindingDB Entry DOI: 10.7270/Q2V69JW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Mus musculus) | BDBM50336694 (3-Benzo[1,3]dioxol-5-yl-4-{3-(2-(2-(2-(2-fluoroeth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 418 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital Mu£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma counting | J Med Chem 54: 939-48 (2011) Article DOI: 10.1021/jm101110w BindingDB Entry DOI: 10.7270/Q2V69JW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Mus musculus) | BDBM50336698 (CHEMBL1672885 | N-[1-(2-{2-[2-(2-{5-[4-Benzo[1,3]d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 893 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital Mu£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma counting | J Med Chem 54: 939-48 (2011) Article DOI: 10.1021/jm101110w BindingDB Entry DOI: 10.7270/Q2V69JW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Mus musculus) | BDBM50336696 (3-Benzo[1,3]dioxol-5-yl-4-[3-(2-{2-[2-(2-{1-[2-(2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital Mu£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma counting | J Med Chem 54: 939-48 (2011) Article DOI: 10.1021/jm101110w BindingDB Entry DOI: 10.7270/Q2V69JW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Mus musculus) | BDBM50336700 (3-Benzo[1,3]dioxol-5-yl-4-{3-[2-(2-{2-[2-(4-fluoro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital Mu£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma counting | J Med Chem 54: 939-48 (2011) Article DOI: 10.1021/jm101110w BindingDB Entry DOI: 10.7270/Q2V69JW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Mus musculus) | BDBM50336695 (3-Benzo[1,3]dioxol-5-yl-4-{3-[1-(2-{2-[2-(2-fluoro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital Mu£nster Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma counting | J Med Chem 54: 939-48 (2011) Article DOI: 10.1021/jm101110w BindingDB Entry DOI: 10.7270/Q2V69JW4 | |||||||||||
More data for this Ligand-Target Pair |