Compile Data Set for Download or QSAR

Found 6 hits of ic50 for UniProtKB: P42225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Signal transducer and activator of transcription 1 (Mus musculus)	BDBM549075 (BDBM50556877 | US11299480, Example 34) Show SMILES OC(=O)c1ccc(cc1O)N(Cc1ccc(cc1)C1CCCCC1)C(=O)[C@H]1CCN1S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F |r| Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT1 homodimer in mouse NIH3T3 nuclear extract preincubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31
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Signal transducer and activator of transcription 1 (Mus musculus)	BDBM549118 (BDBM50556884 | US11299480, Example 53) Show SMILES OC(=O)c1ccc(cc1O)N(Cc1ccc(cn1)C1CCCCC1)C(=O)[C@H]1CCN1S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F |r| Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT1 homodimer in mouse NIH3T3 nuclear extract preincubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 1 (Mus musculus)	BDBM549132 (BDBM50556940 | US11299480, Example 138) Show SMILES Fc1c(F)c(F)c(c(F)c1F)S(=O)(=O)N1CC[C@@H]1C(=O)N(Cc1ccc(cn1)C1CCCCC1)c1ccc2C(=O)NC(=O)c2c1 |r| Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT1 homodimer in mouse NIH3T3 nuclear extract preincubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 1 (Mus musculus)	BDBM50556895 (CHEMBL4760561) Show SMILES OC(=O)c1ccc(N(Cc2ccc(cc2)C2CCCCC2)C(=O)[C@H]2CCN2S(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)c(F)c1 |r| Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT1 homodimer in mouse NIH3T3 nuclear extract preincubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 1 (Mus musculus)	BDBM549125 (BDBM50556925 | US11299480, Example 135) Show SMILES CNC(=O)c1ccc(cc1O)N(Cc1ccc(cn1)C1CCCCC1)C(=O)[C@H]1CCN1S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F |r| Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT1 homodimer in mouse NIH3T3 nuclear extract preincubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 1 (Mus musculus)	BDBM20283 (2-hydroxy-4-(2-{[(4-methylbenzene)sulfonyl]oxy}ace...) Show SMILES Cc1ccc(cc1)S(=O)(=O)OCC(=O)Nc1ccc(C(O)=O)c(O)c1 Show InChI InChI=1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of STAT1 dimerization in EGF-stimulated mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT1-DNA interaction aft...				J Med Chem 55: 6645-68 (2012) Article DOI: 10.1021/jm300207s BindingDB Entry DOI: 10.7270/Q2CJ8FKK
					More data for this Ligand-Target Pair