Compile Data Set for Download or QSAR

Found 53 hits of ic50 for UniProtKB: P49281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361134 (CHEMBL1933609) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C15H12N4O3/c1-10-14(11-5-7-12(8-6-11)19(21)22)15(20)18(17-10)13-4-2-3-9-16-13/h2-9,17H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50387726 (CHEMBL2058878) Show SMILES NC(=N)SCc1cccc2c1oc1c(CSC(N)=N)cccc21 Show InChI InChI=1S/C16H16N4OS2/c17-15(18)22-7-9-3-1-5-11-12-6-2-4-10(8-23-16(19)20)14(12)21-13(9)11/h1-6H,7-8H2,(H3,17,18)(H3,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DMT1 expressed in Xenopus oocytes assessed as inhibition of channel currents at -50 mV holding potential by two-electrode voltage...				Citation and Details Article DOI: 10.1039/d0md00085j BindingDB Entry DOI: 10.7270/Q2J96B1J
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361135 (CHEMBL1933610) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C16H12F3N3O/c1-10-14(11-5-7-12(8-6-11)16(17,18)19)15(23)22(21-10)13-4-2-3-9-20-13/h2-9,21H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361105 (CHEMBL1933782) Show SMILES Cc1ccc2nc(sc2c1)-n1[nH]c2CCc3ccccc3-c2c1=O Show InChI InChI=1S/C19H15N3OS/c1-11-6-8-14-16(10-11)24-19(20-14)22-18(23)17-13-5-3-2-4-12(13)7-9-15(17)21-22/h2-6,8,10,21H,7,9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361122 (CHEMBL1933598) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C17H13F3N4O2/c1-10-14(16(26)24(23-10)13-7-2-3-8-21-13)15(25)22-12-6-4-5-11(9-12)17(18,19)20/h2-9,23H,1H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361123 (CHEMBL1933599) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1C(=O)Nc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C16H13N5O4/c1-10-14(16(23)20(19-10)13-4-2-3-9-17-13)15(22)18-11-5-7-12(8-6-11)21(24)25/h2-9,19H,1H3,(H,18,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361114 (CHEMBL1933791) Show SMILES COc1ccc(cc1)-c1ccc2-c3c(CCc2c1)[nH]n(-c1ccccn1)c3=O Show InChI InChI=1S/C23H19N3O2/c1-28-18-9-5-15(6-10-18)16-7-11-19-17(14-16)8-12-20-22(19)23(27)26(25-20)21-4-2-3-13-24-21/h2-7,9-11,13-14,25H,8,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361115 (CHEMBL1933792) Show SMILES O=c1c-2c(CCc3cc(ccc-23)-c2ccccc2)[nH]n1-c1ccccn1 Show InChI InChI=1S/C22H17N3O/c26-22-21-18-11-9-16(15-6-2-1-3-7-15)14-17(18)10-12-19(21)24-25(22)20-8-4-5-13-23-20/h1-9,11,13-14,24H,10,12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361124 (CHEMBL1933600) Show SMILES COc1ccc(NC(=O)c2c(C)[nH]n(-c3ccccn3)c2=O)cc1F Show InChI InChI=1S/C17H15FN4O3/c1-10-15(17(24)22(21-10)14-5-3-4-8-19-14)16(23)20-11-6-7-13(25-2)12(18)9-11/h3-9,21H,1-2H3,(H,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361116 (CHEMBL1933793) Show SMILES Cc1ccc(cc1)-c1ccc2-c3c(CCc2c1)[nH]n(-c1ccccn1)c3=O Show InChI InChI=1S/C23H19N3O/c1-15-5-7-16(8-6-15)17-9-11-19-18(14-17)10-12-20-22(19)23(27)26(25-20)21-4-2-3-13-24-21/h2-9,11,13-14,25H,10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361125 (CHEMBL1933601) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H13F3N4O2/c1-10-14(16(26)24(23-10)13-4-2-3-9-21-13)15(25)22-12-7-5-11(6-8-12)17(18,19)20/h2-9,23H,1H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361117 (CHEMBL1933794) Show SMILES Brc1ccc2-c3c(CCc2c1)[nH]n(-c1ccccn1)c3=O Show InChI InChI=1S/C16H12BrN3O/c17-11-5-6-12-10(9-11)4-7-13-15(12)16(21)20(19-13)14-3-1-2-8-18-14/h1-3,5-6,8-9,19H,4,7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361136 (CHEMBL1933611) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C16H12F3N3O/c1-10-14(11-5-4-6-12(9-11)16(17,18)19)15(23)22(21-10)13-7-2-3-8-20-13/h2-9,21H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361106 (CHEMBL1933783) Show SMILES COc1ccc2nc(sc2c1)-n1[nH]c2CCc3ccccc3-c2c1=O Show InChI InChI=1S/C19H15N3O2S/c1-24-12-7-9-14-16(10-12)25-19(20-14)22-18(23)17-13-5-3-2-4-11(13)6-8-15(17)21-22/h2-5,7,9-10,21H,6,8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50553222 (CHEMBL1197758) Show SMILES Cc1cc(C)c(CSC(N)=N)c(C)c1CSC(N)=N Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DMT1 expressed in HEK293T cells assessed as inhibition of radiolabeled 55Fe2+ uptake preincubated with compound for 5 mins follow...				Citation and Details Article DOI: 10.1039/d0md00085j BindingDB Entry DOI: 10.7270/Q2J96B1J
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361137 (CHEMBL1933612) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccc(cc1)C#N Show InChI InChI=1S/C16H12N4O/c1-11-15(13-7-5-12(10-17)6-8-13)16(21)20(19-11)14-4-2-3-9-18-14/h2-9,19H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361144 (CHEMBL1933773) Show SMILES Cc1[nH]n(-c2nc3ccc(F)cc3s2)c(=O)c1-c1ccccc1 Show InChI InChI=1S/C17H12FN3OS/c1-10-15(11-5-3-2-4-6-11)16(22)21(20-10)17-19-13-8-7-12(18)9-14(13)23-17/h2-9,20H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361107 (CHEMBL1933784) Show SMILES Fc1ccc2nc(sc2c1)-n1[nH]c2CCc3ccccc3-c2c1=O Show InChI InChI=1S/C18H12FN3OS/c19-11-6-8-13-15(9-11)24-18(20-13)22-17(23)16-12-4-2-1-3-10(12)5-7-14(16)21-22/h1-4,6,8-9,21H,5,7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361126 (CHEMBL1933602) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1C(=O)Nc1cccc(C)c1 Show InChI InChI=1S/C17H16N4O2/c1-11-6-5-7-13(10-11)19-16(22)15-12(2)20-21(17(15)23)14-8-3-4-9-18-14/h3-10,20H,1-2H3,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361145 (CHEMBL1933774) Show SMILES Cc1[nH]n(-c2nc3ccccc3s2)c(=O)c1-c1ccccc1 Show InChI InChI=1S/C17H13N3OS/c1-11-15(12-7-3-2-4-8-12)16(21)20(19-11)17-18-13-9-5-6-10-14(13)22-17/h2-10,19H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361118 (CHEMBL1933795) Show SMILES O=c1c-2c(CCc3cc(ccc-23)C#N)[nH]n1-c1ccccn1 Show InChI InChI=1S/C17H12N4O/c18-10-11-4-6-13-12(9-11)5-7-14-16(13)17(22)21(20-14)15-3-1-2-8-19-15/h1-4,6,8-9,20H,5,7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361146 (CHEMBL1933775) Show SMILES Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1-c1ccccc1 Show InChI InChI=1S/C17H14N4O/c1-11-15(12-7-3-2-4-8-12)16(22)21(20-11)17-18-13-9-5-6-10-14(13)19-17/h2-10,20H,1H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361108 (CHEMBL1933785) Show SMILES OC(=O)c1ccc2nc(sc2c1)-n1[nH]c2CCc3ccccc3-c2c1=O Show InChI InChI=1S/C19H13N3O3S/c23-17-16-12-4-2-1-3-10(12)5-8-14(16)21-22(17)19-20-13-7-6-11(18(24)25)9-15(13)26-19/h1-4,6-7,9,21H,5,8H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361127 (CHEMBL1933603) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1C(=O)Nc1ccccc1 Show InChI InChI=1S/C16H14N4O2/c1-11-14(15(21)18-12-7-3-2-4-8-12)16(22)20(19-11)13-9-5-6-10-17-13/h2-10,19H,1H3,(H,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361128 (CHEMBL1933604) Show SMILES COc1cccc(NC(=O)c2c(C)[nH]n(-c3ccccn3)c2=O)c1 Show InChI InChI=1S/C17H16N4O3/c1-11-15(16(22)19-12-6-5-7-13(10-12)24-2)17(23)21(20-11)14-8-3-4-9-18-14/h3-10,20H,1-2H3,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361129 (CHEMBL1933605) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1C(=O)Nc1ccc(C)cc1 Show InChI InChI=1S/C17H16N4O2/c1-11-6-8-13(9-7-11)19-16(22)15-12(2)20-21(17(15)23)14-5-3-4-10-18-14/h3-10,20H,1-2H3,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361130 (CHEMBL1933606) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1C(=O)Nc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C16H13N5O4/c1-10-14(16(23)20(19-10)13-8-4-5-9-17-13)15(22)18-11-6-2-3-7-12(11)21(24)25/h2-9,19H,1H3,(H,18,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361109 (CHEMBL1933786) Show SMILES O=c1c-2c(CCc3ccccc-23)[nH]n1-c1nc2ccccc2s1 Show InChI InChI=1S/C18H13N3OS/c22-17-16-12-6-2-1-5-11(12)9-10-14(16)20-21(17)18-19-13-7-3-4-8-15(13)23-18/h1-8,20H,9-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361138 (CHEMBL1933613) Show SMILES CCOC(=O)c1ccc(cc1)-c1c(C)[nH]n(-c2ccccn2)c1=O Show InChI InChI=1S/C18H17N3O3/c1-3-24-18(23)14-9-7-13(8-10-14)16-12(2)20-21(17(16)22)15-6-4-5-11-19-15/h4-11,20H,3H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361110 (CHEMBL1933787) Show SMILES O=c1c-2c(CCc3ccccc-23)[nH]n1-c1ccccn1 Show InChI InChI=1S/C16H13N3O/c20-16-15-12-6-2-1-5-11(12)8-9-13(15)18-19(16)14-7-3-4-10-17-14/h1-7,10,18H,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361139 (CHEMBL1933614) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccc(F)cc1 Show InChI InChI=1S/C15H12FN3O/c1-10-14(11-5-7-12(16)8-6-11)15(20)19(18-10)13-4-2-3-9-17-13/h2-9,18H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361131 (CHEMBL1933607) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1C(=O)Nc1ccccc1C(F)(F)F Show InChI InChI=1S/C17H13F3N4O2/c1-10-14(16(26)24(23-10)13-8-4-5-9-21-13)15(25)22-12-7-3-2-6-11(12)17(18,19)20/h2-9,23H,1H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361099 (CHEMBL1933776) Show SMILES COc1ccc2nc(sc2c1)-n1[nH]c(C)c(-c2ccccc2)c1=O Show InChI InChI=1S/C18H15N3O2S/c1-11-16(12-6-4-3-5-7-12)17(22)21(20-11)18-19-14-9-8-13(23-2)10-15(14)24-18/h3-10,20H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361132 (CHEMBL1933608) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1C(=O)Nc1ccc2OCOc2c1 Show InChI InChI=1S/C17H14N4O4/c1-10-15(17(23)21(20-10)14-4-2-3-7-18-14)16(22)19-11-5-6-12-13(8-11)25-9-24-12/h2-8,20H,9H2,1H3,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361121 (CHEMBL1933597) Show SMILES CCN(CC)c1ccc(C=c2c(=C)[nH]n(-c3ccccn3)c2=O)cc1 |w:9.8| Show InChI InChI=1S/C20H22N4O/c1-4-23(5-2)17-11-9-16(10-12-17)14-18-15(3)22-24(20(18)25)19-8-6-7-13-21-19/h6-14,22H,3-5H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361140 (CHEMBL1933615) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccccc1 Show InChI InChI=1S/C15H13N3O/c1-11-14(12-7-3-2-4-8-12)15(19)18(17-11)13-9-5-6-10-16-13/h2-10,17H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361111 (CHEMBL1933788) Show SMILES O=c1c-2c(CCc3ccccc-23)[nH]n1-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C18H14N4O/c23-17-16-12-6-2-1-5-11(12)9-10-15(16)21-22(17)18-19-13-7-3-4-8-14(13)20-18/h1-8,21H,9-10H2,(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50387726 (CHEMBL2058878) Show SMILES NC(=N)SCc1cccc2c1oc1c(CSC(N)=N)cccc21 Show InChI InChI=1S/C16H16N4OS2/c17-15(18)22-7-9-3-1-5-11-12-6-2-4-10(8-23-16(19)20)14(12)21-13(9)11/h1-6H,7-8H2,(H3,17,18)(H3,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DMT1 expressed in HEK293T cells assessed as inhibition of radiolabeled 55Fe2+ uptake preincubated with compound for 5 mins follow...				Citation and Details Article DOI: 10.1039/d0md00085j BindingDB Entry DOI: 10.7270/Q2J96B1J
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361100 (CHEMBL1933777) Show SMILES Cc1[nH]n(-c2nccs2)c(=O)c1-c1ccccc1 Show InChI InChI=1S/C13H11N3OS/c1-9-11(10-5-3-2-4-6-10)12(17)16(15-9)13-14-7-8-18-13/h2-8,15H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM54072 (3-[(4Z)-4-[4-(diethylamino)benzylidene]-5-keto-3-m...) Show SMILES CCN(CC)c1ccc(C=c2c(=C)[nH]n(-c3nnc(C)c(=O)[nH]3)c2=O)cc1 |w:9.8| Show InChI InChI=1S/C19H22N6O2/c1-5-24(6-2)15-9-7-14(8-10-15)11-16-12(3)23-25(18(16)27)19-20-17(26)13(4)21-22-19/h7-11,23H,3,5-6H2,1-2,4H3,(H,20,22,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361119 (CHEMBL1933796) Show SMILES COc1ccc2-c3c(CCc2c1)[nH]n(-c1ccccn1)c3=O Show InChI InChI=1S/C17H15N3O2/c1-22-12-6-7-13-11(10-12)5-8-14-16(13)17(21)20(19-14)15-4-2-3-9-18-15/h2-4,6-7,9-10,19H,5,8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361141 (CHEMBL1933770) Show SMILES COc1ccc(cc1)-c1c(C)[nH]n(-c2ccccn2)c1=O Show InChI InChI=1S/C16H15N3O2/c1-11-15(12-6-8-13(21-2)9-7-12)16(20)19(18-11)14-5-3-4-10-17-14/h3-10,18H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361142 (CHEMBL1933771) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccc(N)cc1 Show InChI InChI=1S/C15H14N4O/c1-10-14(11-5-7-12(16)8-6-11)15(20)19(18-10)13-4-2-3-9-17-13/h2-9,18H,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361143 (CHEMBL1933772) Show SMILES CCN(CC)c1ccc(cc1)-c1c(C)[nH]n(-c2ccccn2)c1=O Show InChI InChI=1S/C19H22N4O/c1-4-22(5-2)16-11-9-15(10-12-16)18-14(3)21-23(19(18)24)17-8-6-7-13-20-17/h6-13,21H,4-5H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361101 (CHEMBL1933778) Show SMILES Cc1[nH]n(Cc2ccccn2)c(=O)c1-c1ccccc1 Show InChI InChI=1S/C16H15N3O/c1-12-15(13-7-3-2-4-8-13)16(20)19(18-12)11-14-9-5-6-10-17-14/h2-10,18H,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361103 (CHEMBL1933780) Show SMILES Cc1[nH]n(-c2cc(O)cnn2)c(=O)c1-c1ccccc1 Show InChI InChI=1S/C14H12N4O2/c1-9-13(10-5-3-2-4-6-10)14(20)18(17-9)12-7-11(19)8-15-16-12/h2-8,17H,1H3,(H,16,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361113 (CHEMBL1933790) Show SMILES Cc1cccc2sc(nc12)-n1[nH]c2CCc3ccccc3-c2c1=O Show InChI InChI=1S/C19H15N3OS/c1-11-5-4-8-15-17(11)20-19(24-15)22-18(23)16-13-7-3-2-6-12(13)9-10-14(16)21-22/h2-8,21H,9-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361112 (CHEMBL1933789) Show SMILES [O-][n+]1ccccc1-n1[nH]c2CCc3ccccc3-c2c1=O Show InChI InChI=1S/C16H13N3O2/c20-16-15-12-6-2-1-5-11(12)8-9-13(15)17-19(16)14-7-3-4-10-18(14)21/h1-7,10,17H,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361104 (CHEMBL1933781) Show SMILES Cc1[nH]n(N2CC=c3ccccc3=C2)c(=O)c1-c1ccccc1 |c:13,t:6| Show InChI InChI=1S/C19H17N3O/c1-14-18(16-8-3-2-4-9-16)19(23)22(20-14)21-12-11-15-7-5-6-10-17(15)13-21/h2-11,13,20H,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361133 (CHEMBL1537201) Show SMILES Cc1[nH]n(-c2ccccc2)c(=O)c1C(=O)Nc1ccccc1 Show InChI InChI=1S/C17H15N3O2/c1-12-15(16(21)18-13-8-4-2-5-9-13)17(22)20(19-12)14-10-6-3-7-11-14/h2-11,19H,1H3,(H,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair

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