Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein-tyrosine-phosphatase (Homo sapiens (Human)) | BDBM50391713 (CHEMBL2146956) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University Curated by ChEMBL | Assay Description Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysis | Bioorg Med Chem Lett 22: 6333-7 (2012) Article DOI: 10.1016/j.bmcl.2012.08.081 BindingDB Entry DOI: 10.7270/Q2HT2QDC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-tyrosine-phosphatase (Homo sapiens (Human)) | BDBM50237957 (4-(2-((2,5-dioxoimidazolidin-4-ylidene)methyl)-1H-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University Curated by ChEMBL | Assay Description Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysis | Bioorg Med Chem Lett 22: 6333-7 (2012) Article DOI: 10.1016/j.bmcl.2012.08.081 BindingDB Entry DOI: 10.7270/Q2HT2QDC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-tyrosine-phosphatase (Homo sapiens (Human)) | BDBM50391714 (CHEMBL2146957) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University Curated by ChEMBL | Assay Description Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysis | Bioorg Med Chem Lett 22: 6333-7 (2012) Article DOI: 10.1016/j.bmcl.2012.08.081 BindingDB Entry DOI: 10.7270/Q2HT2QDC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-tyrosine-phosphatase (Homo sapiens (Human)) | BDBM50391715 (CHEMBL2146960) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University Curated by ChEMBL | Assay Description Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysis | Bioorg Med Chem Lett 22: 6333-7 (2012) Article DOI: 10.1016/j.bmcl.2012.08.081 BindingDB Entry DOI: 10.7270/Q2HT2QDC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-tyrosine-phosphatase (Homo sapiens (Human)) | BDBM50391711 (CHEMBL2146958) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University Curated by ChEMBL | Assay Description Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysis | Bioorg Med Chem Lett 22: 6333-7 (2012) Article DOI: 10.1016/j.bmcl.2012.08.081 BindingDB Entry DOI: 10.7270/Q2HT2QDC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-tyrosine-phosphatase (Homo sapiens (Human)) | BDBM50387974 (CHEMBL2057830) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University Curated by ChEMBL | Assay Description Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysis | Bioorg Med Chem Lett 22: 6333-7 (2012) Article DOI: 10.1016/j.bmcl.2012.08.081 BindingDB Entry DOI: 10.7270/Q2HT2QDC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-tyrosine-phosphatase (Homo sapiens (Human)) | BDBM50391712 (CHEMBL2146959) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University Curated by ChEMBL | Assay Description Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysis | Bioorg Med Chem Lett 22: 6333-7 (2012) Article DOI: 10.1016/j.bmcl.2012.08.081 BindingDB Entry DOI: 10.7270/Q2HT2QDC | |||||||||||
More data for this Ligand-Target Pair |