Compile Data Set for Download or QSAR

Found 8 hits of ec50 data for polymerid = 50006425   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Virulence factor transcriptional regulator MvfR (Pseudomonas aeruginosa PA14)	BDBM50440124 (CHEMBL2426232) Show SMILES Nc1nnc(o1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C9H6F3N3O/c10-9(11,12)6-3-1-2-5(4-6)7-14-15-8(13)16-7/h1-4H,(H2,13,15)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a
Helmholtz-Institute for Pharmaceutical Research Saarland Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...				J Med Chem 56: 6761-74 (2013) Article DOI: 10.1021/jm400830r BindingDB Entry DOI: 10.7270/Q2T72JV2
					More data for this Ligand-Target Pair
Virulence factor transcriptional regulator MvfR (Pseudomonas aeruginosa PA14)	BDBM50440129 (CHEMBL2426231) Show SMILES Nc1nnc(o1)-c1cccc(Br)c1 Show InChI InChI=1S/C8H6BrN3O/c9-6-3-1-2-5(4-6)7-11-12-8(10)13-7/h1-4H,(H2,10,12)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a
Helmholtz-Institute for Pharmaceutical Research Saarland Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...				J Med Chem 56: 6761-74 (2013) Article DOI: 10.1021/jm400830r BindingDB Entry DOI: 10.7270/Q2T72JV2
					More data for this Ligand-Target Pair
Virulence factor transcriptional regulator MvfR (Pseudomonas aeruginosa PA14)	BDBM50440126 (CHEMBL2426233) Show SMILES Nc1nnc(o1)-c1cccc(c1)C#N Show InChI InChI=1S/C9H6N4O/c10-5-6-2-1-3-7(4-6)8-12-13-9(11)14-8/h1-4H,(H2,11,13)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a
Helmholtz-Institute for Pharmaceutical Research Saarland Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...				J Med Chem 56: 6761-74 (2013) Article DOI: 10.1021/jm400830r BindingDB Entry DOI: 10.7270/Q2T72JV2
					More data for this Ligand-Target Pair
Virulence factor transcriptional regulator MvfR (Pseudomonas aeruginosa PA14)	BDBM50440125 (CHEMBL2426228) Show SMILES Nc1nnc(o1)-c1cccc(Cl)c1 Show InChI InChI=1S/C8H6ClN3O/c9-6-3-1-2-5(4-6)7-11-12-8(10)13-7/h1-4H,(H2,10,12)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.67E+4	n/a	n/a	n/a	n/a
Helmholtz-Institute for Pharmaceutical Research Saarland Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...				J Med Chem 56: 6761-74 (2013) Article DOI: 10.1021/jm400830r BindingDB Entry DOI: 10.7270/Q2T72JV2
					More data for this Ligand-Target Pair
Virulence factor transcriptional regulator MvfR (Pseudomonas aeruginosa PA14)	BDBM50440124 (CHEMBL2426232) Show SMILES Nc1nnc(o1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C9H6F3N3O/c10-9(11,12)6-3-1-2-5(4-6)7-14-15-8(13)16-7/h1-4H,(H2,13,15)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.85E+4	n/a	n/a	n/a	n/a
Helmholtz-Institute for Pharmaceutical Research Saarland Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in pqs gene-deficient Pseudomonas aeruginosa PA14 by beta-galactosidase reporter ge...				J Med Chem 56: 6761-74 (2013) Article DOI: 10.1021/jm400830r BindingDB Entry DOI: 10.7270/Q2T72JV2
					More data for this Ligand-Target Pair
Virulence factor transcriptional regulator MvfR (Pseudomonas aeruginosa PA14)	BDBM50440123 (CHEMBL2426234) Show SMILES Nc1nnc(o1)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C9H6F3N3O2/c10-9(11,12)17-6-3-1-2-5(4-6)7-14-15-8(13)16-7/h1-4H,(H2,13,15)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.65E+4	n/a	n/a	n/a	n/a
Helmholtz-Institute for Pharmaceutical Research Saarland Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...				J Med Chem 56: 6761-74 (2013) Article DOI: 10.1021/jm400830r BindingDB Entry DOI: 10.7270/Q2T72JV2
					More data for this Ligand-Target Pair
Virulence factor transcriptional regulator MvfR (Pseudomonas aeruginosa PA14)	BDBM50440122 (CHEMBL2426235) Show SMILES Cc1cccc(c1)-c1nnc(N)o1 Show InChI InChI=1S/C9H9N3O/c1-6-3-2-4-7(5-6)8-11-12-9(10)13-8/h2-5H,1H3,(H2,10,12)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.78E+4	n/a	n/a	n/a	n/a
Helmholtz-Institute for Pharmaceutical Research Saarland Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...				J Med Chem 56: 6761-74 (2013) Article DOI: 10.1021/jm400830r BindingDB Entry DOI: 10.7270/Q2T72JV2
					More data for this Ligand-Target Pair
Virulence factor transcriptional regulator MvfR (Pseudomonas aeruginosa PA14)	BDBM50440121 (CHEMBL2426237 | US11634391, Compound 117) Show SMILES FC(F)(F)c1cccc(c1)-c1nnco1 Show InChI InChI=1S/C9H5F3N2O/c10-9(11,12)7-3-1-2-6(4-7)8-14-13-5-15-8/h1-5H	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.01E+5	n/a	n/a	n/a	n/a
Helmholtz-Institute for Pharmaceutical Research Saarland Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...				J Med Chem 56: 6761-74 (2013) Article DOI: 10.1021/jm400830r BindingDB Entry DOI: 10.7270/Q2T72JV2
					More data for this Ligand-Target Pair