Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tumor necrosis factor ligand superfamily member 11 (Mus musculus) | BDBM50128343 (CHEMBL3629176) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Sookmyung Women's University Curated by ChEMBL | Assay Description Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat... | Bioorg Med Chem 23: 7069-78 (2015) Article DOI: 10.1016/j.bmc.2015.09.025 BindingDB Entry DOI: 10.7270/Q23N256M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tumor necrosis factor ligand superfamily member 11 (Mus musculus) | BDBM50128344 (CHEMBL3629177) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
Sookmyung Women's University Curated by ChEMBL | Assay Description Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat... | Bioorg Med Chem 23: 7069-78 (2015) Article DOI: 10.1016/j.bmc.2015.09.025 BindingDB Entry DOI: 10.7270/Q23N256M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tumor necrosis factor ligand superfamily member 11 (Mus musculus) | BDBM50128235 (CHEMBL3628709) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University Curated by ChEMBL | Assay Description Inhibition of M-CSF/sRANKL-induced mouse BMDM differentiation into osteoclast after 72 hrs by TRAP staining-based microscopic analysis | Bioorg Med Chem Lett 25: 5295-8 (2015) Article DOI: 10.1016/j.bmcl.2015.09.044 BindingDB Entry DOI: 10.7270/Q2GX4DCP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tumor necrosis factor ligand superfamily member 11 (Mus musculus) | BDBM50128342 (CHEMBL3629175) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sookmyung Women's University Curated by ChEMBL | Assay Description Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat... | Bioorg Med Chem 23: 7069-78 (2015) Article DOI: 10.1016/j.bmc.2015.09.025 BindingDB Entry DOI: 10.7270/Q23N256M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tumor necrosis factor ligand superfamily member 11 (Mus musculus) | BDBM50108929 (CHEMBL3596956) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Taipei Medical University Curated by ChEMBL | Assay Description Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ... | Bioorg Med Chem 23: 4522-32 (2015) Article DOI: 10.1016/j.bmc.2015.06.007 BindingDB Entry DOI: 10.7270/Q2V126KK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tumor necrosis factor ligand superfamily member 11 (Mus musculus) | BDBM50108928 (CHEMBL3596954) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Taipei Medical University Curated by ChEMBL | Assay Description Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ... | Bioorg Med Chem 23: 4522-32 (2015) Article DOI: 10.1016/j.bmc.2015.06.007 BindingDB Entry DOI: 10.7270/Q2V126KK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tumor necrosis factor ligand superfamily member 11 (Mus musculus) | BDBM50108927 (CHEMBL3596952) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Taipei Medical University Curated by ChEMBL | Assay Description Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ... | Bioorg Med Chem 23: 4522-32 (2015) Article DOI: 10.1016/j.bmc.2015.06.007 BindingDB Entry DOI: 10.7270/Q2V126KK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tumor necrosis factor ligand superfamily member 11 (Mus musculus) | BDBM50108930 (CHEMBL3335186) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Taipei Medical University Curated by ChEMBL | Assay Description Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ... | Bioorg Med Chem 23: 4522-32 (2015) Article DOI: 10.1016/j.bmc.2015.06.007 BindingDB Entry DOI: 10.7270/Q2V126KK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tumor necrosis factor ligand superfamily member 11 (Mus musculus) | BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sookmyung Women's University Curated by ChEMBL | Assay Description Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat... | Bioorg Med Chem 23: 7069-78 (2015) Article DOI: 10.1016/j.bmc.2015.09.025 BindingDB Entry DOI: 10.7270/Q23N256M | |||||||||||
More data for this Ligand-Target Pair |