Search and Browse
Download
Enter Data
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Interleukin-6 receptor subunit beta (Homo sapiens (Human)) | BDBM50552020 (CHEMBL4777424) | PDB UniProtKB/SwissProt GoogleScholar AffyNet  | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to immobilized GP130 (unknown origin) by SPR analysis | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112375 BindingDB Entry DOI: 10.7270/Q27948B6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-6 receptor subunit beta (Homo sapiens (Human)) | BDBM50552019 (CHEMBL4740172) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.43E+5 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to immobilized GP130 (unknown origin) by SPR analysis | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112375 BindingDB Entry DOI: 10.7270/Q27948B6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-6 receptor subunit beta (Homo sapiens (Human)) | BDBM50496302 (MADINDOLINE A) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.88E+5 | n/a | n/a | n/a | n/a | n/a |
The Ohio State University Curated by ChEMBL | Assay Description Binding affinity to GP130 (unknown origin) by surface plasmon resonance analysis | J Med Chem 57: 632-41 (2014) Article DOI: 10.1021/jm401144z BindingDB Entry DOI: 10.7270/Q2B27Z87 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
