Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium channel subfamily K member 10 (Homo sapiens (Human)) | BDBM25759 (CHEMBL723 | Carvedilol | Coreg | Dilatrend | Eucar...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Clermont Auvergne Curated by ChEMBL | Assay Description Inhibition of of TREK2 (unknown origin) expressed in HEK293 cells assessed as reduction in channel currents | J Med Chem 59: 5149-57 (2016) Article DOI: 10.1021/acs.jmedchem.5b00671 BindingDB Entry DOI: 10.7270/Q2319XSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium channel subfamily K member 10 (Homo sapiens (Human)) | BDBM25759 (CHEMBL723 | Carvedilol | Coreg | Dilatrend | Eucar...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Clermont Auvergne Curated by ChEMBL | Assay Description Inhibition of of TREK2 (unknown origin) expressed in oocytes assessed as reduction in channel currents | J Med Chem 59: 5149-57 (2016) Article DOI: 10.1021/acs.jmedchem.5b00671 BindingDB Entry DOI: 10.7270/Q2319XSS | |||||||||||
More data for this Ligand-Target Pair |