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Compile Data Set for Download or QSAR

Found 6 hits of ec50 data for polymerid = 50007165   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Steroid hormone receptor ERR2


(Homo sapiens (Human))
BDBM50455427
PNG
(CHEMBL4206963)
Show SMILES Cc1cc(O)ccc1C(=O)NCCc1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C20H25NO2/c1-14-13-17(22)9-10-18(14)19(23)21-12-11-15-5-7-16(8-6-15)20(2,3)4/h5-10,13,22H,11-12H2,1-4H3,(H,21,23)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 20n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at alphaHis-SUMO-tagged ERRbeta-LBD (unknown origin) assessed as decrease in RIP140 peptide recruitment by TR-FRET assay


Bioorg Med Chem Lett 28: 1313-1319 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.019
BindingDB Entry DOI: 10.7270/Q2RF5XKM
More data for this
Ligand-Target Pair
Steroid hormone receptor ERR2


(Homo sapiens (Human))
BDBM50455420
PNG
(CHEMBL4217033)
Show SMILES CC(C)(C)c1ccc(CCNC(=O)c2ccc(O)cc2Cl)cc1
Show InChI InChI=1S/C19H22ClNO2/c1-19(2,3)14-6-4-13(5-7-14)10-11-21-18(23)16-9-8-15(22)12-17(16)20/h4-9,12,22H,10-11H2,1-3H3,(H,21,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 31n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at alphaHis-SUMO-tagged ERRbeta-LBD (unknown origin) assessed as decrease in RIP140 peptide recruitment by TR-FRET assay


Bioorg Med Chem Lett 28: 1313-1319 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.019
BindingDB Entry DOI: 10.7270/Q2RF5XKM
More data for this
Ligand-Target Pair
Steroid hormone receptor ERR2


(Homo sapiens (Human))
BDBM50455417
PNG
(CHEMBL4211016)
Show SMILES CC(C)(C)c1ccc(CCNC(=O)c2ccc(O)cc2N)cc1
Show InChI InChI=1S/C19H24N2O2/c1-19(2,3)14-6-4-13(5-7-14)10-11-21-18(23)16-9-8-15(22)12-17(16)20/h4-9,12,22H,10-11,20H2,1-3H3,(H,21,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 45n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at alphaHis-SUMO-tagged ERRbeta-LBD (unknown origin) assessed as decrease in RIP140 peptide recruitment by TR-FRET assay


Bioorg Med Chem Lett 28: 1313-1319 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.019
BindingDB Entry DOI: 10.7270/Q2RF5XKM
More data for this
Ligand-Target Pair
Steroid hormone receptor ERR2


(Homo sapiens (Human))
BDBM50455402
PNG
(CHEMBL4204689)
Show SMILES CC(C)(C)c1ccc(CCNC(=O)c2ccc(O)cc2)cc1
Show InChI InChI=1S/C19H23NO2/c1-19(2,3)16-8-4-14(5-9-16)12-13-20-18(22)15-6-10-17(21)11-7-15/h4-11,21H,12-13H2,1-3H3,(H,20,22)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 90n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at alphaHis-SUMO-tagged ERRbeta-LBD (unknown origin) assessed as decrease in RIP140 peptide recruitment by TR-FRET assay


Bioorg Med Chem Lett 28: 1313-1319 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.019
BindingDB Entry DOI: 10.7270/Q2RF5XKM
More data for this
Ligand-Target Pair
Steroid hormone receptor ERR2


(Homo sapiens (Human))
BDBM50455428
PNG
(CHEMBL4205664)
Show SMILES CCN(CC)c1ccc(CCNC(=O)c2ccc(O)cc2)cc1
Show InChI InChI=1S/C19H24N2O2/c1-3-21(4-2)17-9-5-15(6-10-17)13-14-20-19(23)16-7-11-18(22)12-8-16/h5-12,22H,3-4,13-14H2,1-2H3,(H,20,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 630n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at alphaHis-SUMO-tagged ERRbeta-LBD (unknown origin) assessed as decrease in RIP140 peptide recruitment by TR-FRET assay


Bioorg Med Chem Lett 28: 1313-1319 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.019
BindingDB Entry DOI: 10.7270/Q2RF5XKM
More data for this
Ligand-Target Pair
Steroid hormone receptor ERR2


(Homo sapiens (Human))
BDBM50455406
PNG
(CHEMBL4211789)
Show SMILES CC(C)(C)c1ccc(CCNC(=O)Cc2ccc(O)cc2)cc1
Show InChI InChI=1S/C20H25NO2/c1-20(2,3)17-8-4-15(5-9-17)12-13-21-19(23)14-16-6-10-18(22)11-7-16/h4-11,22H,12-14H2,1-3H3,(H,21,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.70E+3n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at alphaHis-SUMO-tagged ERRbeta-LBD (unknown origin) assessed as decrease in RIP140 peptide recruitment by TR-FRET assay


Bioorg Med Chem Lett 28: 1313-1319 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.019
BindingDB Entry DOI: 10.7270/Q2RF5XKM
More data for this
Ligand-Target Pair