Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenylate cyclase type 8 (Homo sapiens (Human)) | BDBM50010261 ((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 94 | n/a | n/a | n/a | n/a |
Kunming Medical University Curated by ChEMBL | Assay Description Agonist activity at recombinant human AC8 expressed in human HEK293 cells assessed as fold increase in cAMP level by LANCE Ultra cAMP Detection kit m... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126823 BindingDB Entry DOI: 10.7270/Q2Q52T4B | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Adenylate cyclase type 8 (Homo sapiens (Human)) | BDBM50537925 (CHEMBL4644318) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 105 | n/a | n/a | n/a | n/a |
Kunming Medical University Curated by ChEMBL | Assay Description Agonist activity at recombinant human AC8 expressed in human HEK293 cells assessed as fold increase in cAMP level by LANCE Ultra cAMP Detection kit m... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126823 BindingDB Entry DOI: 10.7270/Q2Q52T4B | |||||||||||
More data for this Ligand-Target Pair |