Found 45 hits of ic50 for UniProtKB: P48056 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473314
(CHEMBL553068)Show SMILES Cl.OC(=O)CC1CCN(CCOCCN2c3ccccc3CCc3ccccc23)C1 Show InChI InChI=1S/C24H30N2O3.ClH/c27-24(28)17-19-11-12-25(18-19)13-15-29-16-14-26-22-7-3-1-5-20(22)9-10-21-6-2-4-8-23(21)26;/h1-8,19H,9-18H2,(H,27,28);1H | UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50081891
((R)-1-[2-(3,3-Diphenyl-propoxy)-ethyl]-piperidine-...)Show SMILES OC(=O)[C@@H]1CCCN(CCOCCC(c2ccccc2)c2ccccc2)C1 Show InChI InChI=1S/C23H29NO3/c25-23(26)21-12-7-14-24(18-21)15-17-27-16-13-22(19-8-3-1-4-9-19)20-10-5-2-6-11-20/h1-6,8-11,21-22H,7,12-18H2,(H,25,26)/t21-/m1/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473316
(CHEMBL545694)Show SMILES Cl.OC(=O)[C@@H]1CCCN(CCOCCN2c3cc(Cl)ccc3CCc3ccc(Cl)cc23)C1 |r| Show InChI InChI=1S/C24H28Cl2N2O3.ClH/c25-20-7-5-17-3-4-18-6-8-21(26)15-23(18)28(22(17)14-20)11-13-31-12-10-27-9-1-2-19(16-27)24(29)30;/h5-8,14-15,19H,1-4,9-13,16H2,(H,29,30);1H/t19-;/m1./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473312
(CHEMBL543108)Show SMILES Cl.OC(=O)[C@@H]1CCCN(CCOCCN2c3ccccc3CCc3ccc(Cl)cc23)C1 |r| Show InChI InChI=1S/C24H29ClN2O3.ClH/c25-21-10-9-19-8-7-18-4-1-2-6-22(18)27(23(19)16-21)13-15-30-14-12-26-11-3-5-20(17-26)24(28)29;/h1-2,4,6,9-10,16,20H,3,5,7-8,11-15,17H2,(H,28,29);1H/t20-;/m1./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50080346
((R)-1-(2-Benzhydrylideneaminooxy-ethyl)-piperidine...)Show SMILES [#8]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7](-[#6]-[#6]-[#8]\[#7]=[#6](/c2ccccc2)-c2ccccc2)-[#6]-1 Show InChI InChI=1S/C21H24N2O3/c24-21(25)19-12-7-13-23(16-19)14-15-26-22-20(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-6,8-11,19H,7,12-16H2,(H,24,25)/t19-/m1/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50081888
((R)-1-[2-(2-Diphenylamino-ethoxy)-ethyl]-piperidin...)Show SMILES OC(=O)[C@@H]1CCCN(CCOCCN(c2ccccc2)c2ccccc2)C1 Show InChI InChI=1S/C22H28N2O3/c25-22(26)19-8-7-13-23(18-19)14-16-27-17-15-24(20-9-3-1-4-10-20)21-11-5-2-6-12-21/h1-6,9-12,19H,7-8,13-18H2,(H,25,26)/t19-/m1/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473321
(CHEMBL563076)Show SMILES Cl.OC(=O)[C@@H]1CCCN(CCOCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)C1 |r| Show InChI InChI=1S/C23H25F3N2O3S.ClH/c24-23(25,26)17-7-8-21-19(14-17)28(18-5-1-2-6-20(18)32-21)11-13-31-12-10-27-9-3-4-16(15-27)22(29)30;/h1-2,5-8,14,16H,3-4,9-13,15H2,(H,29,30);1H/t16-;/m1./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50437146
(CHEMBL1189315)Show SMILES OC(=O)[C@@H]1CCCN(CCOCCN2c3ccccc3CCc3ccccc23)C1 |r| Show InChI InChI=1S/C24H30N2O3/c27-24(28)21-8-5-13-25(18-21)14-16-29-17-15-26-22-9-3-1-6-19(22)11-12-20-7-2-4-10-23(20)26/h1-4,6-7,9-10,21H,5,8,11-18H2,(H,27,28)/t21-/m1/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 184 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473306
(CHEMBL556178)Show SMILES Cl.OC(=O)[C@@H]1CCCN(CCOCCN2c3ccc(F)cc3CCc3cc(F)ccc23)C1 |r| Show InChI InChI=1S/C24H28F2N2O3.ClH/c25-20-5-7-22-17(14-20)3-4-18-15-21(26)6-8-23(18)28(22)11-13-31-12-10-27-9-1-2-19(16-27)24(29)30;/h5-8,14-15,19H,1-4,9-13,16H2,(H,29,30);1H/t19-;/m1./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 248 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473319
(CHEMBL555856)Show SMILES Cl.OC(=O)[C@@H]1CCCN(CCOCCN2c3ccccc3CCc3ccc(F)cc23)C1 |r| Show InChI InChI=1S/C24H29FN2O3.ClH/c25-21-10-9-19-8-7-18-4-1-2-6-22(18)27(23(19)16-21)13-15-30-14-12-26-11-3-5-20(17-26)24(28)29;/h1-2,4,6,9-10,16,20H,3,5,7-8,11-15,17H2,(H,28,29);1H/t20-;/m1./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 265 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50437144
(CHEMBL1190271)Show SMILES OC(=O)[C@@H]1CCCN(CCOCCN2c3ccccc3Sc3ccccc23)C1 |r| Show InChI InChI=1S/C22H26N2O3S/c25-22(26)17-6-5-11-23(16-17)12-14-27-15-13-24-18-7-1-3-9-20(18)28-21-10-4-2-8-19(21)24/h1-4,7-10,17H,5-6,11-16H2,(H,25,26)/t17-/m1/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 308 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50003634
(1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carboxyli...)Show SMILES [#8]-[#6](=O)-[#6]-1-[#6]-[#6]-[#6]-[#7](-[#6]-[#6]\[#6]=[#6](\c2ccccc2)-c2ccccc2)-[#6]-1 Show InChI InChI=1S/C22H25NO2/c24-22(25)20-13-7-15-23(17-20)16-8-14-21(18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-6,9-12,14,20H,7-8,13,15-17H2,(H,24,25) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473315
(CHEMBL541561)Show SMILES Cl.[#8]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#8]-[#6]\[#6]=[#6]-2\c3ccccc3-[#6]-[#6]-c3ccccc-23)-[#6]-1 |r| Show InChI InChI=1S/C26H31NO3.ClH/c28-26(29)22-9-5-15-27(19-22)16-6-17-30-18-14-25-23-10-3-1-7-20(23)12-13-21-8-2-4-11-24(21)25;/h1-4,7-8,10-11,14,22H,5-6,9,12-13,15-19H2,(H,28,29);1H/t22-;/m1./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473313
(CHEMBL545690)Show SMILES Cl.OC(=O)[C@H]1CCCN(CCOCCC2c3ccccc3CCc3ccccc23)C1 |r| Show InChI InChI=1S/C25H31NO3.ClH/c27-25(28)21-8-5-14-26(18-21)15-17-29-16-13-24-22-9-3-1-6-19(22)11-12-20-7-2-4-10-23(20)24;/h1-4,6-7,9-10,21,24H,5,8,11-18H2,(H,27,28);1H/t21-;/m0./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 561 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473311
(CHEMBL543342)Show SMILES Cl.OC(=O)C1=CCCN(CCOCCN2c3ccccc3CCc3ccccc23)C1 |t:3| Show InChI InChI=1S/C24H28N2O3/c27-24(28)21-8-5-13-25(18-21)14-16-29-17-15-26-22-9-3-1-6-19(22)11-12-20-7-2-4-10-23(20)26/h1-4,6-10H,5,11-18H2,(H,27,28) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 644 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50437145
(CHEMBL1196076)Show SMILES OC(=O)[C@@H]1CCCN(CCOCCN2c3ccccc3C=Cc3ccccc23)C1 |r,c:21| Show InChI InChI=1S/C24H28N2O3/c27-24(28)21-8-5-13-25(18-21)14-16-29-17-15-26-22-9-3-1-6-19(22)11-12-20-7-2-4-10-23(20)26/h1-4,6-7,9-12,21H,5,8,13-18H2,(H,27,28)/t21-/m1/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 647 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473317
(CHEMBL553053)Show SMILES Cl.OC(=O)[C@@H]1CCCN(CCOCCCN2c3ccccc3CCc3ccccc23)C1 |r| Show InChI InChI=1S/C25H32N2O3.ClH/c28-25(29)22-9-5-14-26(19-22)16-18-30-17-6-15-27-23-10-3-1-7-20(23)12-13-21-8-2-4-11-24(21)27;/h1-4,7-8,10-11,22H,5-6,9,12-19H2,(H,28,29);1H/t22-;/m1./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 696 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473320
(CHEMBL545452)Show SMILES Cl.[#8]-[#6](=O)-[#6@H]-1-[#6]-[#6]-[#6]-[#7](-[#6]-[#6]-[#8]-[#6]\[#6]=[#6]-2\c3ccccc3-[#6]-[#6]-c3ccccc-23)-[#6]-1 |r| Show InChI InChI=1S/C25H29NO3.ClH/c27-25(28)21-8-5-14-26(18-21)15-17-29-16-13-24-22-9-3-1-6-19(22)11-12-20-7-2-4-10-23(20)24;/h1-4,6-7,9-10,13,21H,5,8,11-12,14-18H2,(H,27,28);1H/t21-;/m0./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473309
(CHEMBL552675)Show SMILES Cl.OC(=O)[C@@H]1CCCN(CCOCCN2c3ccccc3CCCc3ccccc23)C1 |r| Show InChI InChI=1S/C25H32N2O3.ClH/c28-25(29)22-11-6-14-26(19-22)15-17-30-18-16-27-23-12-3-1-7-20(23)9-5-10-21-8-2-4-13-24(21)27;/h1-4,7-8,12-13,22H,5-6,9-11,14-19H2,(H,28,29);1H/t22-;/m1./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 851 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473302
(CHEMBL555631)Show SMILES Cl.[#8]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7](-[#6]-[#6]-[#8]\[#7]=[#6]-2/c3ccccc3-[#6]-[#6]-c3ccccc-23)-[#6]-1 |r| Show InChI InChI=1S/C23H26N2O3.ClH/c26-23(27)19-8-5-13-25(16-19)14-15-28-24-22-20-9-3-1-6-17(20)11-12-18-7-2-4-10-21(18)22;/h1-4,6-7,9-10,19H,5,8,11-16H2,(H,26,27);1H/t19-;/m1./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473303
(CHEMBL542641)Show SMILES Cl.OC(=O)C1=CN(CCOCCC2c3ccccc3CCc3ccccc23)CCC1 |t:3| Show InChI InChI=1S/C25H29NO3/c27-25(28)21-8-5-14-26(18-21)15-17-29-16-13-24-22-9-3-1-6-19(22)11-12-20-7-2-4-10-23(20)24/h1-4,6-7,9-10,18,24H,5,8,11-17H2,(H,27,28) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50003653
(1-(2-Benzhydryloxy-ethyl)-piperidine-3-carboxylic ...)Show InChI InChI=1S/C21H25NO3/c23-21(24)19-12-7-13-22(16-19)14-15-25-20(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-6,8-11,19-20H,7,12-16H2,(H,23,24) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50226144
(2,4-Diamino-Butyric Acid | CHEBI:64307 | CHEMBL307...)Show InChI InChI=1S/C4H10N2O2/c5-2-1-3(6)4(7)8/h3H,1-2,5-6H2,(H,7,8) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Similars
| PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibition of rat neuronal (synaptosomal) GABA uptake. |
J Med Chem 29: 224-9 (1986)
BindingDB Entry DOI: 10.7270/Q2FX7CNP |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50078167
(CHEMBL69064)Show SMILES [#8]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7](-[#6]-[#6]\[#6]=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-1 Show InChI InChI=1S/C22H23NO2/c24-22(25)16-7-5-13-23(15-16)14-6-12-21-19-10-3-1-8-17(19)18-9-2-4-11-20(18)21/h1-4,8-12,16H,5-7,13-15H2,(H,24,25)/t16-/m1/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473308
(CHEMBL541821)Show SMILES Cl.OC(=O)[C@H]1CCCN(CCOC\C=C2/c3ccccc3CCc3ccc(Cl)cc23)C1 |r| Show InChI InChI=1S/C25H28ClNO3.ClH/c26-21-10-9-19-8-7-18-4-1-2-6-22(18)23(24(19)16-21)11-14-30-15-13-27-12-3-5-20(17-27)25(28)29;/h1-2,4,6,9-11,16,20H,3,5,7-8,12-15,17H2,(H,28,29);1H/b23-11+;/t20-;/m0./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473305
(CHEMBL71789)Show SMILES OC(=O)C1CCCN(CCOC2c3ccccc3C=Cc3ccccc23)C1 |c:19| Show InChI InChI=1S/C23H25NO3/c25-23(26)19-8-5-13-24(16-19)14-15-27-22-20-9-3-1-6-17(20)11-12-18-7-2-4-10-21(18)22/h1-4,6-7,9-12,19,22H,5,8,13-16H2,(H,25,26) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473318
(CHEMBL539773)Show SMILES Cl.[#8]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7](-[#6]-[#6]-[#8]\[#7]=[#6]-2\c3cc(Cl)ccc3-[#6]-[#6]-c3ccc(Cl)cc-23)-[#6]-1 |r| Show InChI InChI=1S/C23H24Cl2N2O3.ClH/c24-18-7-5-15-3-4-16-6-8-19(25)13-21(16)22(20(15)12-18)26-30-11-10-27-9-1-2-17(14-27)23(28)29;/h5-8,12-13,17H,1-4,9-11,14H2,(H,28,29);1H/t17-;/m1./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50003624
((RS)-nipecotic acid | CHEMBL277498 | Nipecotic | P...)Show InChI InChI=1S/C6H11NO2/c8-6(9)5-2-1-3-7-4-5/h5,7H,1-4H2,(H,8,9) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane |
J Med Chem 25: 1157-62 (1982)
BindingDB Entry DOI: 10.7270/Q2FF3VK7 |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50223874
(CHEMBL277372)Show InChI InChI=1S/C6H11NO3/c8-5-1-2-7-3-4(5)6(9)10/h4-5,7-8H,1-3H2,(H,9,10)/t4-,5+/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane |
J Med Chem 25: 1157-62 (1982)
BindingDB Entry DOI: 10.7270/Q2FF3VK7 |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473310
(CHEMBL303402)Show SMILES [#8]-[#6](=O)-[#6]-1-[#6]-[#6]-[#6]-[#7](-[#6]-[#6]\[#6]=[#6]-2\c3ccccc3-[#6]-[#6]-c3ccccc-23)-[#6]-1 Show InChI InChI=1S/C24H27NO2/c26-24(27)20-9-5-15-25(17-20)16-6-12-23-21-10-3-1-7-18(21)13-14-19-8-2-4-11-22(19)23/h1-4,7-8,10-12,20H,5-6,9,13-17H2,(H,26,27) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473307
(CHEMBL545692)Show SMILES Cl.OC(=O)[C@@H]1CCCN(CCOCCN2c3ccccc3Oc3ccccc23)C1 |r| Show InChI InChI=1S/C22H26N2O4.ClH/c25-22(26)17-6-5-11-23(16-17)12-14-27-15-13-24-18-7-1-3-9-20(18)28-21-10-4-2-8-19(21)24;/h1-4,7-10,17H,5-6,11-16H2,(H,25,26);1H/t17-;/m1./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50473304
(CHEMBL541556)Show SMILES Cl.OC(=O)[C@@H]1CCCN(CCOCCn2c3ccccc3c3ccccc23)C1 |r| Show InChI InChI=1S/C22H26N2O3.ClH/c25-22(26)17-6-5-11-23(16-17)12-14-27-15-13-24-20-9-3-1-7-18(20)19-8-2-4-10-21(19)24;/h1-4,7-10,17H,5-6,11-16H2,(H,25,26);1H/t17-;/m1./s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined |
J Med Chem 44: 2152-63 (2001)
Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50226141
(CHEMBL309688)Show InChI InChI=1S/C6H8N2O2/c9-6-4-3-7-2-1-5(4)8-10-6/h7,9H,1-3H2 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibition of rat neuronal (synaptosomal) GABA uptake. |
J Med Chem 29: 224-9 (1986)
BindingDB Entry DOI: 10.7270/Q2FX7CNP |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50226145
(CHEMBL150830)Show InChI InChI=1S/C6H8N2O2/c9-6-4-3-7-2-1-5(4)10-8-6/h7H,1-3H2,(H,8,9) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibition of rat neuronal (synaptosomal) GABA uptake. |
J Med Chem 29: 224-9 (1986)
BindingDB Entry DOI: 10.7270/Q2FX7CNP |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50223872
(CHEMBL15851)Show InChI InChI=1S/C6H11NO3/c8-5-1-4(6(9)10)2-7-3-5/h4-5,7-8H,1-3H2,(H,9,10)/t4-,5+/m1/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.73E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane |
J Med Chem 25: 1157-62 (1982)
BindingDB Entry DOI: 10.7270/Q2FF3VK7 |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50223876
(CHEMBL16226)Show InChI InChI=1S/C6H11NO3/c8-5-1-2-7-3-4(5)6(9)10/h4-5,7-8H,1-3H2,(H,9,10)/t4-,5-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.03E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane |
J Med Chem 25: 1157-62 (1982)
BindingDB Entry DOI: 10.7270/Q2FF3VK7 |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50223871
(CHEMBL429974)Show InChI InChI=1S/C8H14N2O3/c1-5(11)10-7-2-6(8(12)13)3-9-4-7/h6-7,9H,2-4H2,1H3,(H,10,11)(H,12,13)/t6-,7+/m1/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane |
J Med Chem 25: 1157-62 (1982)
BindingDB Entry DOI: 10.7270/Q2FF3VK7 |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50224808
(CHEMBL309689)Show InChI InChI=1S/C7H10N2O2/c10-7-5-1-3-8-4-2-6(5)11-9-7/h8H,1-4H2,(H,9,10) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibition of rat neuronal (synaptosomal) GABA uptake. |
J Med Chem 29: 224-9 (1986)
BindingDB Entry DOI: 10.7270/Q2FX7CNP |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50226143
(CHEMBL305673)Show InChI InChI=1S/C7H10N2O2/c10-7-5-4-8-3-1-2-6(5)9-11-7/h8,10H,1-4H2 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibition of rat neuronal (synaptosomal) GABA uptake. |
J Med Chem 29: 224-9 (1986)
BindingDB Entry DOI: 10.7270/Q2FX7CNP |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50226142
(CHEMBL292757)Show InChI InChI=1S/C7H10N2O2/c10-7-5-1-3-8-4-2-6(5)9-11-7/h8,10H,1-4H2 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibition of rat neuronal (synaptosomal) GABA uptake. |
J Med Chem 29: 224-9 (1986)
BindingDB Entry DOI: 10.7270/Q2FX7CNP |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50000106
(4-CARBOXYPIPERIDINE | CHEMBL279998 | Piperidine-4-...)Show InChI InChI=1S/C6H11NO2/c8-6(9)5-1-3-7-4-2-5/h5,7H,1-4H2,(H,8,9) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
| PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane |
J Med Chem 25: 1157-62 (1982)
BindingDB Entry DOI: 10.7270/Q2FF3VK7 |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50223875
(CHEMBL280511)Show InChI InChI=1S/C8H14N2O3/c1-5(11)10-7-2-3-9-4-6(7)8(12)13/h6-7,9H,2-4H2,1H3,(H,10,11)(H,12,13)/t6-,7+/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane |
J Med Chem 25: 1157-62 (1982)
BindingDB Entry DOI: 10.7270/Q2FF3VK7 |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50226146
(CHEMBL74364)Show InChI InChI=1S/C7H10N2O2/c10-7-5-2-1-3-8-4-6(5)9-11-7/h8,10H,1-4H2 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibition of rat neuronal (synaptosomal) GABA uptake. |
J Med Chem 29: 224-9 (1986)
BindingDB Entry DOI: 10.7270/Q2FX7CNP |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50223873
(CHEMBL16357)Show InChI InChI=1S/C6H11NO3/c8-5-3-7-2-1-4(5)6(9)10/h4-5,7-8H,1-3H2,(H,9,10)/t4-,5-/m1/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane |
J Med Chem 25: 1157-62 (1982)
BindingDB Entry DOI: 10.7270/Q2FF3VK7 |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent betaine transporter
(Rattus norvegicus) | BDBM50223877
(CHEMBL16132)Show InChI InChI=1S/C6H11NO3/c8-5-3-7-2-1-4(5)6(9)10/h4-5,7-8H,1-3H2,(H,9,10)/t4-,5+/m1/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane |
J Med Chem 25: 1157-62 (1982)
BindingDB Entry DOI: 10.7270/Q2FF3VK7 |
More data for this
Ligand-Target Pair | |
Search and Browse
