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Compile Data Set for Download or QSAR

Found 25 hits of ic50 for UniProtKB: P40933   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-15


(Homo sapiens)
BDBM50571062
PNG
(CHEMBL4857666)
Show SMILES Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(cc1)C(=O)c1ccccc1
PDB

UniProtKB/SwissProt

GoogleScholar
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PC sid
UniChem
Article
PubMed
n/an/a 50n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50238649
PNG
(CHEMBL4103753)
Show SMILES Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C27H30Cl2N6O2S/c1-34-24(17-23-19-10-7-8-11-20(19)26(37)35(2)33-23)31-32-27(34)38-15-9-5-3-4-6-12-25(36)30-22-14-13-18(28)16-21(22)29/h7-8,10-11,13-14,16H,3-6,9,12,15,17H2,1-2H3,(H,30,36)
PDB

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UniChem

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Article
PubMed
n/an/a 190n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571051
PNG
(CHEMBL4846844)
Show SMILES Cn1nc(Cc2nnc(SCCCCCCCC(=O)Nc3ccc(Cl)cc3Cl)[nH]2)c2ccccc2c1=O
PDB

UniProtKB/SwissProt

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UniChem
Article
PubMed
n/an/a 280n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571050
PNG
(CHEMBL4851186)
Show SMILES Cn1nc(Cc2nnc(SCCCCCCCC(=O)Nc3ccc(Cl)cc3Cl)n2CCC=O)c2ccccc2c1=O
PDB

UniProtKB/SwissProt

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PubMed
n/an/a 710n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571041
PNG
(CHEMBL4864820)
Show SMILES Cn1nc(Cc2nnc(SCC(=O)Nc3ccc(Cl)cc3Cl)n2CCC=O)c2ccccc2c1=O
PDB

UniProtKB/SwissProt

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UniChem
Article
PubMed
n/an/a 4.20E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50238648
PNG
(CHEMBL4102828)
Show SMILES Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCC(=O)Nc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C21H18Cl2N6O2S/c1-28-18(10-17-13-5-3-4-6-14(13)20(31)29(2)27-17)25-26-21(28)32-11-19(30)24-16-8-7-12(22)9-15(16)23/h3-9H,10-11H2,1-2H3,(H,24,30)
PDB

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CHEMBL
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Patents


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Article
PubMed
n/an/a 4.50E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571054
PNG
(CHEMBL4864898)
Show SMILES Cn1nc(Cc2nnc(SCCCCCCCC(=O)Nc3ccc(Cl)cc3Cl)n2CCC(O)=O)c2ccccc2c1=O
PDB

UniProtKB/SwissProt

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Article
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n/an/a 9.50E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571057
PNG
(CHEMBL4847472)
Show SMILES Cn1c(Cc2nn(CCC=O)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl
PDB

UniProtKB/SwissProt

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Article
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n/an/a 1.49E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571045
PNG
(CHEMBL4848978)
Show SMILES Cn1c(Cc2nn(CCC=O)c(=O)c3ccccc23)nnc1SCC(=O)Nc1ccc(Cl)cc1Cl
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571061
PNG
(CHEMBL4861648)
Show SMILES Cn1c(Cc2n[nH]c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571047
PNG
(CHEMBL4856031)
Show SMILES Cn1c(Cc2nn(CCC(O)=O)c(=O)c3ccccc23)nnc1SCC(=O)Nc1ccc(Cl)cc1Cl
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571048
PNG
(CHEMBL4849059)
Show SMILES CN(C)CCCn1nc(Cc2nnc(SCC(=O)Nc3ccc(Cl)cc3Cl)n2C)c2ccccc2c1=O
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571046
PNG
(CHEMBL4875914)
Show SMILES Cn1c(Cc2nn(CCCO)c(=O)c3ccccc23)nnc1SCC(=O)Nc1ccc(Cl)cc1Cl
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571044
PNG
(CHEMBL4878149)
Show SMILES Cn1c(Cc2nn(CCC3OCCO3)c(=O)c3ccccc23)nnc1SCC(=O)Nc1ccc(Cl)cc1Cl
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571052
PNG
(CHEMBL4869889)
Show SMILES [#6]-n1nc(-[#6]-c2nnc(-[#16]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c3ccc(Cl)cc3Cl)n2-[#6]-[#6]-[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])c2ccccc2c1=O
PDB

UniProtKB/SwissProt

GoogleScholar
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PC sid
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Article
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n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571053
PNG
(CHEMBL4858180)
Show SMILES Cn1nc(Cc2nnc(SCCCCCCCC(=O)Nc3ccc(Cl)cc3Cl)n2CCCO)c2ccccc2c1=O
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571043
PNG
(CHEMBL4857570)
Show SMILES Cn1nc(Cc2nnc(SCC(=O)Nc3ccc(Cl)cc3Cl)n2CCC(O)=O)c2ccccc2c1=O
PDB

UniProtKB/SwissProt

GoogleScholar
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PC sid
UniChem
Article
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n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571055
PNG
(CHEMBL4878834)
Show SMILES CN(C)CCCn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl
PDB

UniProtKB/SwissProt

GoogleScholar
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PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571056
PNG
(CHEMBL4863838)
Show SMILES [#6]-n1c(-[#6]-c2nn(-[#6]-[#6]-[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])c(=O)c3ccccc23)nnc1-[#16]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(Cl)cc1Cl
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
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Article
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n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571042
PNG
(CHEMBL4849548)
Show SMILES Cn1nc(Cc2nnc(SCC(=O)Nc3ccc(Cl)cc3Cl)n2CCCO)c2ccccc2c1=O
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571058
PNG
(CHEMBL4852416)
Show SMILES Cn1c(Cc2nn(CCCO)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571059
PNG
(CHEMBL4877071)
Show SMILES Cn1c(Cc2nn(CCC(O)=O)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl
PDB

UniProtKB/SwissProt

GoogleScholar
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PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571060
PNG
(CHEMBL4862957)
Show SMILES CN(C)CCCn1nc(Cc2nnc(SCCCCCCCC(=O)Nc3ccc(Cl)cc3Cl)n2C)c2ccccc2c1=O
PDB

UniProtKB/SwissProt

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PC sid
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Article
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n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571040
PNG
(CHEMBL4867872)
Show SMILES CCOC(CCn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCC(=O)Nc1ccc(Cl)cc1Cl)OCC
PDB

UniProtKB/SwissProt

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n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair
Interleukin-15


(Homo sapiens)
BDBM50571049
PNG
(CHEMBL4868024)
Show SMILES CCOC(CCn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl)OCC
PDB

UniProtKB/SwissProt

GoogleScholar
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PC sid
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Article
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n/an/a 3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...


Citation and Details

Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47
More data for this
Ligand-Target Pair