Found 20 hits of kd for UniProtKB: P40933 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Interleukin-15
(Homo sapiens) | BDBM50238649
(CHEMBL4103753)Show SMILES Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl Show InChI InChI=1S/C27H30Cl2N6O2S/c1-34-24(17-23-19-10-7-8-11-20(19)26(37)35(2)33-23)31-32-27(34)38-15-9-5-3-4-6-12-25(36)30-22-14-13-18(28)16-21(22)29/h7-8,10-11,13-14,16H,3-6,9,12,15,17H2,1-2H3,(H,30,36) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to recombinant human IL-15 assessed as dissociation constant by SPR analysis |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47 |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50571051
(CHEMBL4846844)Show SMILES Cn1nc(Cc2nnc(SCCCCCCCC(=O)Nc3ccc(Cl)cc3Cl)[nH]2)c2ccccc2c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to recombinant human IL-15 assessed as dissociation constant by SPR analysis |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47 |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50571062
(CHEMBL4857666)Show SMILES Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(cc1)C(=O)c1ccccc1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to recombinant human IL-15 assessed as dissociation constant by SPR analysis |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47 |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50571058
(CHEMBL4852416)Show SMILES Cn1c(Cc2nn(CCCO)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to recombinant human IL-15 assessed as dissociation constant by SPR analysis |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47 |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50571050
(CHEMBL4851186)Show SMILES Cn1nc(Cc2nnc(SCCCCCCCC(=O)Nc3ccc(Cl)cc3Cl)n2CCC=O)c2ccccc2c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to recombinant human IL-15 assessed as dissociation constant by SPR analysis |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47 |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50571057
(CHEMBL4847472)Show SMILES Cn1c(Cc2nn(CCC=O)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to recombinant human IL-15 assessed as dissociation constant by SPR analysis |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116161
BindingDB Entry DOI: 10.7270/Q2FF3X47 |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238650
(CHEMBL4085144)Show SMILES Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Br)cc1Br Show InChI InChI=1S/C27H30Br2N6O2S/c1-34-24(17-23-19-10-7-8-11-20(19)26(37)35(2)33-23)31-32-27(34)38-15-9-5-3-4-6-12-25(36)30-22-14-13-18(28)16-21(22)29/h7-8,10-11,13-14,16H,3-6,9,12,15,17H2,1-2H3,(H,30,36) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant human IL-15 by SPR assay |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238658
(CHEMBL4067098)Show SMILES Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCCCCC(=O)NC12CC3CC(CC(C3)C1)C2 |THB:38:37:34:40.39.41,38:39:36.37.42:34,41:39:36:42.33.34,41:33:36:40.38.39| Show InChI InChI=1S/C34H48N6O2S/c1-39-30(20-29-27-13-10-11-14-28(27)32(42)40(2)38-29)36-37-33(39)43-16-12-8-6-4-3-5-7-9-15-31(41)35-34-21-24-17-25(22-34)19-26(18-24)23-34/h10-11,13-14,24-26H,3-9,12,15-23H2,1-2H3,(H,35,41) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant human IL-15 by SPR assay |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238644
(CHEMBL4096400)Show SMILES CCCOc1ccc(NC(=O)CCCCCCCSc2nnc(Cc3nn(C)c(=O)c4ccccc34)n2C)cc1 Show InChI InChI=1S/C30H38N6O3S/c1-4-19-39-23-17-15-22(16-18-23)31-28(37)14-8-6-5-7-11-20-40-30-33-32-27(35(30)2)21-26-24-12-9-10-13-25(24)29(38)36(3)34-26/h9-10,12-13,15-18H,4-8,11,14,19-21H2,1-3H3,(H,31,37) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Inhibition of noradrenaline uptake in rat synaptosomal fraction |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238649
(CHEMBL4103753)Show SMILES Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl Show InChI InChI=1S/C27H30Cl2N6O2S/c1-34-24(17-23-19-10-7-8-11-20(19)26(37)35(2)33-23)31-32-27(34)38-15-9-5-3-4-6-12-25(36)30-22-14-13-18(28)16-21(22)29/h7-8,10-11,13-14,16H,3-6,9,12,15,17H2,1-2H3,(H,30,36) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.91E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant human IL-15 by SPR assay |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238652
(CHEMBL4066271)Show SMILES COc1ccc(NC(=O)CCCCCCCSc2nnc(Cc3nn(C)c(=O)c4ccccc34)n2C)c(OC)c1 Show InChI InChI=1S/C29H36N6O4S/c1-34-26(19-24-21-12-9-10-13-22(21)28(37)35(2)33-24)31-32-29(34)40-17-11-7-5-6-8-14-27(36)30-23-16-15-20(38-3)18-25(23)39-4/h9-10,12-13,15-16,18H,5-8,11,14,17,19H2,1-4H3,(H,30,36) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.96E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant human IL-15 by SPR assay |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238645
(CHEMBL4069144)Show SMILES CC(C)Oc1ccc(NC(=O)CCCCCCCSc2nnc(Cc3nn(C)c(=O)c4ccccc34)n2C)cc1 Show InChI InChI=1S/C30H38N6O3S/c1-21(2)39-23-17-15-22(16-18-23)31-28(37)14-8-6-5-7-11-19-40-30-33-32-27(35(30)3)20-26-24-12-9-10-13-25(24)29(38)36(4)34-26/h9-10,12-13,15-18,21H,5-8,11,14,19-20H2,1-4H3,(H,31,37) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.09E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant human IL-15 by SPR assay |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238651
(CHEMBL4093847)Show SMILES COc1ccc(NC(=O)CCCCCCCSc2nnc(Cc3nn(C)c(=O)c4ccccc34)n2C)c(O)c1 Show InChI InChI=1S/C28H34N6O4S/c1-33-25(18-23-20-11-8-9-12-21(20)27(37)34(2)32-23)30-31-28(33)39-16-10-6-4-5-7-13-26(36)29-22-15-14-19(38-3)17-24(22)35/h8-9,11-12,14-15,17,35H,4-7,10,13,16,18H2,1-3H3,(H,29,36) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.12E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Inhibition of noradrenaline uptake in rat synaptosomal fraction |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238646
(CHEMBL4101389)Show SMILES CCOC(=O)c1cccc(NC(=O)CCCCCCCSc2nnc(Cc3nn(C)c(=O)c4ccccc34)n2C)c1 Show InChI InChI=1S/C30H36N6O4S/c1-4-40-29(39)21-13-12-14-22(19-21)31-27(37)17-8-6-5-7-11-18-41-30-33-32-26(35(30)2)20-25-23-15-9-10-16-24(23)28(38)36(3)34-25/h9-10,12-16,19H,4-8,11,17-18,20H2,1-3H3,(H,31,37) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.18E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant human IL-15 by SPR assay |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238664
(CHEMBL4101575)Show SMILES Cc1ccc(NC(=O)CCCCCCCSc2nnc(Cc3nn(C)c(=O)c4ccccc34)n2C)c(Cl)c1 Show InChI InChI=1S/C28H33ClN6O2S/c1-19-14-15-23(22(29)17-19)30-26(36)13-7-5-4-6-10-16-38-28-32-31-25(34(28)2)18-24-20-11-8-9-12-21(20)27(37)35(3)33-24/h8-9,11-12,14-15,17H,4-7,10,13,16,18H2,1-3H3,(H,30,36) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.41E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant human IL-15 by SPR assay |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238681
(CHEMBL4070160)Show SMILES CC(C)COc1ccc(NC(=O)CCCCCCCSc2nnc(Cc3nn(C)c(=O)c4ccccc34)n2C)cc1 Show InChI InChI=1S/C31H40N6O3S/c1-22(2)21-40-24-17-15-23(16-18-24)32-29(38)14-8-6-5-7-11-19-41-31-34-33-28(36(31)3)20-27-25-12-9-10-13-26(25)30(39)37(4)35-27/h9-10,12-13,15-18,22H,5-8,11,14,19-21H2,1-4H3,(H,32,38) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant human IL-15 by SPR assay |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238643
(CHEMBL4088685)Show SMILES COc1ccc(NC(=O)CCCCCCCSc2nnc(Cc3nn(C)c(=O)c4ccccc34)n2C)cc1 Show InChI InChI=1S/C28H34N6O3S/c1-33-25(19-24-22-11-8-9-12-23(22)27(36)34(2)32-24)30-31-28(33)38-18-10-6-4-5-7-13-26(35)29-20-14-16-21(37-3)17-15-20/h8-9,11-12,14-17H,4-7,10,13,18-19H2,1-3H3,(H,29,35) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant human IL-15 by SPR assay |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238642
(CHEMBL4087773)Show SMILES Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(cc1)N=[N+]=[N-] Show InChI InChI=1S/C27H31N9O2S/c1-35-24(18-23-21-10-7-8-11-22(21)26(38)36(2)33-23)31-32-27(35)39-17-9-5-3-4-6-12-25(37)29-19-13-15-20(16-14-19)30-34-28/h7-8,10-11,13-16H,3-6,9,12,17-18H2,1-2H3,(H,29,37) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | 4.24E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant human IL-15 by SPR assay |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238648
(CHEMBL4102828)Show SMILES Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCC(=O)Nc1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H18Cl2N6O2S/c1-28-18(10-17-13-5-3-4-6-14(13)20(31)29(2)27-17)25-26-21(28)32-11-19(30)24-16-8-7-12(22)9-15(16)23/h3-9H,10-11H2,1-2H3,(H,24,30) | PDB
UniProtKB/SwissProt
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PC sid
UniChem
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Similars
| Article
PubMed
| n/a | n/a | n/a | 4.84E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant human IL-15 by SPR assay |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
Interleukin-15
(Homo sapiens) | BDBM50238647
(CHEMBL4066088)Show SMILES Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)NC12CC3CC(CC(C3)C1)C2 |THB:35:34:31:37.36.38,35:36:33.34.39:31,38:36:33:39.30.31,38:30:33:37.35.36| Show InChI InChI=1S/C31H42N6O2S/c1-36-27(17-26-24-10-7-8-11-25(24)29(39)37(2)35-26)33-34-30(36)40-13-9-5-3-4-6-12-28(38)32-31-18-21-14-22(19-31)16-23(15-21)20-31/h7-8,10-11,21-23H,3-6,9,12-20H2,1-2H3,(H,32,38) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant human IL-15 by SPR assay |
J Med Chem 60: 6249-6272 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00485
BindingDB Entry DOI: 10.7270/Q20V8G2Z |
More data for this
Ligand-Target Pair | |
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