Compile Data Set for Download or QSAR

Found 454 hits of kd for UniProtKB: P41182   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B-cell lymphoma 6 protein (Homo sapiens)	BDBM50260529 (CHEMBL4077626) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(O)=O |r| Show InChI InChI=1S/C83H121N21O20S/c1-10-44(6)67(102-76(118)62(38-65(109)110)99-79(121)68(45(7)106)103-75(117)59(35-47-25-27-50(108)28-26-47)96-74(116)61(37-49-40-91-54-21-14-12-19-52(49)54)97-72(114)58(34-42(2)3)92-46(8)107)78(120)95-55(22-15-30-88-82(84)85)69(111)94-57(29-33-125-9)70(112)100-63(41-105)77(119)98-60(36-48-39-90-53-20-13-11-18-51(48)53)73(115)93-56(23-16-31-89-83(86)87)71(113)101-66(43(4)5)80(122)104-32-17-24-64(104)81(123)124/h11-14,18-21,25-28,39-40,42-45,55-64,66-68,90-91,105-106,108H,10,15-17,22-24,29-38,41H2,1-9H3,(H,92,107)(H,93,115)(H,94,111)(H,95,120)(H,96,116)(H,97,114)(H,98,119)(H,99,121)(H,100,112)(H,101,113)(H,102,118)(H,103,117)(H,109,110)(H,123,124)(H4,84,85,88)(H4,86,87,89)/t44-,45+,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,66-,67-,68-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of BCOR binding to recombinant biotinylated SUMO-tagged BCL6 BTB domain (5 to 129 amino acid residues) (unknown origin) expressed in Esche...				J Med Chem 60: 4358-4368 (2017) Article DOI: 10.1021/acs.jmedchem.7b00313 BindingDB Entry DOI: 10.7270/Q2VM4FQW
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM50260529 (CHEMBL4077626) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(O)=O |r| Show InChI InChI=1S/C83H121N21O20S/c1-10-44(6)67(102-76(118)62(38-65(109)110)99-79(121)68(45(7)106)103-75(117)59(35-47-25-27-50(108)28-26-47)96-74(116)61(37-49-40-91-54-21-14-12-19-52(49)54)97-72(114)58(34-42(2)3)92-46(8)107)78(120)95-55(22-15-30-88-82(84)85)69(111)94-57(29-33-125-9)70(112)100-63(41-105)77(119)98-60(36-48-39-90-53-20-13-11-18-51(48)53)73(115)93-56(23-16-31-89-83(86)87)71(113)101-66(43(4)5)80(122)104-32-17-24-64(104)81(123)124/h11-14,18-21,25-28,39-40,42-45,55-64,66-68,90-91,105-106,108H,10,15-17,22-24,29-38,41H2,1-9H3,(H,92,107)(H,93,115)(H,94,111)(H,95,120)(H,96,116)(H,97,114)(H,98,119)(H,99,121)(H,100,112)(H,101,113)(H,102,118)(H,103,117)(H,109,110)(H,123,124)(H4,84,85,88)(H4,86,87,89)/t44-,45+,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,66-,67-,68-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a
J. Uriach & Cia SA Curated by ChEMBL					Assay Description In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...				J Med Chem 39: 2197-206 (1996) Article DOI: 10.1021/jm9508853
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM50260529 (CHEMBL4077626) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(O)=O |r| Show InChI InChI=1S/C83H121N21O20S/c1-10-44(6)67(102-76(118)62(38-65(109)110)99-79(121)68(45(7)106)103-75(117)59(35-47-25-27-50(108)28-26-47)96-74(116)61(37-49-40-91-54-21-14-12-19-52(49)54)97-72(114)58(34-42(2)3)92-46(8)107)78(120)95-55(22-15-30-88-82(84)85)69(111)94-57(29-33-125-9)70(112)100-63(41-105)77(119)98-60(36-48-39-90-53-20-13-11-18-51(48)53)73(115)93-56(23-16-31-89-83(86)87)71(113)101-66(43(4)5)80(122)104-32-17-24-64(104)81(123)124/h11-14,18-21,25-28,39-40,42-45,55-64,66-68,90-91,105-106,108H,10,15-17,22-24,29-38,41H2,1-9H3,(H,92,107)(H,93,115)(H,94,111)(H,95,120)(H,96,116)(H,97,114)(H,98,119)(H,99,121)(H,100,112)(H,101,113)(H,102,118)(H,103,117)(H,109,110)(H,123,124)(H4,84,85,88)(H4,86,87,89)/t44-,45+,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,66-,67-,68-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Binding affinity to biotinylated BCL6 (unknown origin) by SPR analysis				Bioorg Med Chem 25: 4876-4886 (2017) Article DOI: 10.1016/j.bmc.2017.07.037 BindingDB Entry DOI: 10.7270/Q2G44SR7
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM50602180 (CHEMBL5195604) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(C)=O)[C@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01433 BindingDB Entry DOI: 10.7270/Q2JM2FPW
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM50602180 (CHEMBL5195604) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(C)=O)[C@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01433 BindingDB Entry DOI: 10.7270/Q2JM2FPW
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582302 (US11518764, Compound I-311 | acsmedchemlett.2c0050...) Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2nc(C)n(C)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.04	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582458 (US11518764, Compound I-471 | acsmedchemlett.2c0050...) Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2ncn(C)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.05	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582362 (US11518764, Compound I-375) Show SMILES COCCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2ncn(C)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.31	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582149 (US11518764, Compound I-158) Show SMILES Cn1cnc2n(CC(=O)Nc3cc(ncc3Cl)N3C[C@H]4CCO[C@H]4C3)cc(-c3cc(F)c(O)c(c3)C(N)=O)c2c1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.76	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582344 (US11518764, Compound I-357) Show SMILES CCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2ncn(C)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.86	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582443 (US11518764, Compound I-456) Show SMILES CC1N=CC(=N1)C#CCn1cnc2n(CC(=O)Nc3cc(nc(F)c3Cl)N3CCN(C)C[C@@H]3C)cc(-c3cc(C(N)=O)c(O)c(F)c3F)c2c1=O |r,c:2,4| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.87	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582103 (US11518764, Compound I-74) Show SMILES Cn1cnc2n(CC(=O)Nc3cc(ncc3Cl)N3C[C@H]4CCO[C@H]4C3)cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c2c1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582299 (US11518764, Compound I-308) Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2nc(C)n(C)c3=O)c(Cl)cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.05	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582221 (US11518764, Compound I-230) Show SMILES C[C@H]1CNCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2nc(C)n(C)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.32	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582415 (US11518764, Compound I-428) Show SMILES CCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.35	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582419 (US11518764, Compound I-432) Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2ncn(CC#Cc2cnn(C)c2)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.39	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582425 (US11518764, Compound I-438) Show SMILES C[C@H]1CN(CCN1c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)c(F)n1)C1COC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582409 (US11518764, Compound I-422 | acsmedchemlett.2c0050...) Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.64	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582403 (US11518764, Compound I-416) Show SMILES COCCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.73	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582336 (US11518764, Compound I-349) Show SMILES C[C@H]1CNCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2ncn(C)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	3.29	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582435 (US11518764, Compound I-448) Show SMILES COCCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	3.42	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582310 (US11518764, Compound I-319) Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	3.96	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582144 (US11518764, Compound I-153) Show SMILES COc1cc(cc(C(N)=O)c1O)-c1cn(CC(=O)Nc2cc(ncc2Cl)N2CCOC[C@@H]2C)c2ncn(C)c(=O)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	4.14	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582198 (US11518764, Compound I-207) Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2nc(C)n(C)c3=O)c(Cl)cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	4.45	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582465 (US11518764, Compound I-478) Show SMILES CN1CCN(CC1)c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2ncn(CC#Cc2cnn(C)c2)c3=O)c(Cl)cn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	4.58	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582266 (US11518764, Compound I-275) Show SMILES Cn1cnc2n(CC(=O)Nc3cc(ncc3Cl)N3CC4COCC4C3)cc(-c3cc(F)c(O)c(c3)C(N)=O)c2c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	4.76	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582233 (US11518764, Compound I-242) Show SMILES NC(=O)c1cc(cc(Cl)c1O)-c1cn(CC(=O)Nc2cc(ncc2Cl)N2CC3CCC(C2)O3)c2nc[nH]c(=O)c12 |TLB:20:25:32:28.29| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582293 (US11518764, Compound I-302) Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2ncn(C)c3=O)c(Cl)cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.05	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582410 (US11518764, Compound I-423) Show SMILES CN(C)c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)c(F)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.06	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582264 (US11518764, Compound I-273) Show SMILES Cn1cnc2n(CC(=O)Nc3cc(ncc3Cl)N3CCCC3)cc(-c3cc(F)c(O)c(c3)C(N)=O)c2c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.31	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582421 (US11518764, Compound I-434) Show SMILES C[C@H]1CN(CCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc(C)n(C)c3=O)c(Cl)c(F)n1)C1COC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.45	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582406 (US11518764, Compound I-419) Show SMILES Cn1cnc2n(CC(=O)Nc3cc(nc(F)c3Cl)N3CCCC3)cc(-c3cc(F)c(O)c(c3)C(N)=O)c2c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.85	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582168 (US11518764, Compound I-177) Show SMILES CN1CCOC2(CCN(C2)c2cc(NC(=O)Cn3cc(-c4cc(F)c(O)c(c4)C(N)=O)c4c3ncn(C)c4=O)c(Cl)cn2)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.88	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582402 (US11518764, Compound I-415) Show SMILES COCCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.95	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582360 (US11518764, Compound I-373) Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc(C)n(C)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.96	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582107 (US11518764, Compound I-82) Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2ncn(CC#Cc2cnn(C)c2)c3=O)c(Cl)cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582113 (US11518764, Compound I-122) Show SMILES COc1cc(cc(C(N)=O)c1O)-c1cn(CC(=O)Nc2cc(ncc2Cl)N2CCOC[C@@H]2C)c2nc(C)n(C)c(=O)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582167 (US11518764, Compound I-176) Show SMILES Cn1cnc2n(CC(=O)Nc3cc(ncc3Cl)N3CC4CCC(C3)O4)cc(-c3cc(F)c(O)c(c3)C(N)=O)c2c1=O |TLB:12:17:24:20.21| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6.06	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582136 (US11518764, Compound I-145) Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc[nH]c3=O)c(Cl)cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6.09	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582148 (US11518764, Compound I-157) Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582332 (US11518764, Compound I-345) Show SMILES C[C@H]1CN(CCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)cn1)C1COC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6.15	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582400 (US11518764, Compound I-413) Show SMILES C[C@H]1CN(CCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)c(F)n1)C1COC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6.15	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582377 (US11518764, Compound I-390) Show SMILES CCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6.18	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582294 (US11518764, Compound I-303) Show SMILES C[C@H]1CN(CC2CC2)CCN1c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6.36	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM50239363 (CHEMBL4094351) Show SMILES [H][C@]12C[C@@H](CO)N(C1)c1cc(Nc3cc4CCC(=O)Nc4c(OC\C=C\CO2)c3)n2ncc(C#N)c2n1 |r,t:26| Show InChI InChI=1S/C25H25N7O4/c26-11-16-12-27-32-22-10-21(29-25(16)32)31-13-19(9-18(31)14-33)35-5-1-2-6-36-20-8-17(28-22)7-15-3-4-23(34)30-24(15)20/h1-2,7-8,10,12,18-19,28,33H,3-6,9,13-14H2,(H,30,34)/b2-1+/t18-,19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a
J. Uriach & Cia SA Curated by ChEMBL					Assay Description In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...				J Med Chem 39: 2197-206 (1996) Article DOI: 10.1021/jm9508853
					More data for this Ligand-Target Pair				3D Structure (crystal)
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582446 (US11518764, Compound I-459) Show SMILES C[C@H]1CN(CC(O)CCO)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2ncn(C)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6.55	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582295 (US11518764, Compound I-304) Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2ncn(CC#Cc2cnn(C)c2)c3=O)c(Cl)cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6.56	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582114 (US11518764, Compound I-123) Show SMILES COc1cc(cc(C(N)=O)c1O)-c1cn(CC(=O)Nc2cc(ncc2Cl)N2CCOCC2)c2nc(C)n(C)c(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582378 (US11518764, Compound I-391) Show SMILES CC(C1CC1)N1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2ncn(C)c3=O)c(Cl)cn1 |r,w:1.0| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	7.26	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair
B-cell lymphoma 6 protein (Homo sapiens)	BDBM582433 (US11518764, Compound I-446) Show SMILES COCCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2ncn(C)c3=O)c(Cl)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	7.29	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B92WK
					More data for this Ligand-Target Pair

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