BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits of kd for UniProtKB: P07437   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin beta chain


(Homo sapiens)		BDBM50501218
PNG
(CHEMBL3917601)
Show SMILES [H][C@]12C[C@H](OC(C)=O)\C=C\C(\C)=C\C[C@H](O)\C=C\C(\C)=C\[C@@H](NC(=O)C(C)O)[C@](C)(C(=O)O1)C(=O)[C@@H]2C |r,t:8,11,16,19|
Show InChI InChI=1S/C27H37NO8/c1-15-7-10-20(31)11-8-16(2)13-23(28-25(33)18(4)29)27(6)24(32)17(3)22(36-26(27)34)14-21(12-9-15)35-19(5)30/h7-9,11-13,17-18,20-23,29,31H,10,14H2,1-6H3,(H,28,33)/b11-8+,12-9+,15-7+,16-13+/t17-,18?,20+,21-,22-,23-,27+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 6.54E+5n/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant tubulin alpha 1A/tubulin beta chain after 30 mins by fluorescence quenching assay

J Med Chem 59: 9532-9540 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01264
BindingDB Entry DOI: 10.7270/Q21N845D
More data for this
Ligand-Target Pair
Tubulin beta chain


(Homo sapiens)		BDBM50501217
PNG
(CHEMBL4298925)
Show SMILES [H][C@]12C[C@]([H])(O)C=C\C(C)=C\C[C@]([H])(O)C=C\C(C)=C\[C@@]([H])(NC(=O)C(C)=O)[C@](C)(C(=O)O1)C(=O)[C@]2([H])C |r,t:9,18|
Show InChI InChI=1S/C25H33NO7/c1-14-6-9-18(28)10-8-15(2)12-21(26-23(31)17(4)27)25(5)22(30)16(3)20(33-24(25)32)13-19(29)11-7-14/h6-8,10-12,16,18-21,28-29H,9,13H2,1-5H3,(H,26,31)/b10-8?,11-7+,14-6+,15-12+/t16-,18+,19-,20-,21-,25+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 1.06E+6n/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant tubulin alpha 1A/tubulin beta chain after 30 mins by fluorescence quenching assay

J Med Chem 59: 9532-9540 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01264
BindingDB Entry DOI: 10.7270/Q21N845D
More data for this
Ligand-Target Pair