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Compile Data Set for Download or QSAR

Found 3 hits of ec50 for UniProtKB: E9PU00   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel, subfamily V, member 3


(Rattus norvegicus)
BDBM50285610
PNG
(CBV | CHEMBL4170268)
Show SMILES CCCc1cc(O)c-2c(OC(C)(C)c3ccc(C)cc-23)c1
Show InChI InChI=1S/C19H22O2/c1-5-6-13-10-16(20)18-14-9-12(2)7-8-15(14)19(3,4)21-17(18)11-13/h7-11,20H,5-6H2,1-4H3
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UniProtKB/TrEMBL

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PC sid
UniChem

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Article
PubMed
n/an/an/an/a 3.50E+3n/an/an/an/a



University of Eastern Piedmont

Curated by ChEMBL


Assay Description
Agonist activity at recombinant rat TRPV3 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluor...


J Nat Prod 81: 630-633 (2018)


Article DOI: 10.1021/acs.jnatprod.7b00946
BindingDB Entry DOI: 10.7270/Q26D5WJF
More data for this
Ligand-Target Pair
Transient receptor potential cation channel, subfamily V, member 3


(Rattus norvegicus)
BDBM50061117
PNG
(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Show SMILES CCCCCc1cc(O)c-2c(OC(C)(C)c3ccc(C)cc-23)c1
Show InChI InChI=1S/C21H26O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9-13,22H,5-8H2,1-4H3
PDB

UniProtKB/TrEMBL

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CHEMBL
KEGG
PC cid
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Article
PubMed
n/an/an/an/a 5.30E+3n/an/an/an/a



University of Eastern Piedmont

Curated by ChEMBL


Assay Description
Agonist activity at recombinant rat TRPV3 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluor...


J Nat Prod 81: 630-633 (2018)


Article DOI: 10.1021/acs.jnatprod.7b00946
BindingDB Entry DOI: 10.7270/Q26D5WJF
More data for this
Ligand-Target Pair
Transient receptor potential cation channel, subfamily V, member 3


(Rattus norvegicus)
BDBM50463447
PNG
(CHEMBL4249046)
Show SMILES [H][C@]12Cc3c(O)cc(CCCCC)cc3O[C@@]1(C)CCCC2(C)C |r|
Show InChI InChI=1S/C21H32O2/c1-5-6-7-9-15-12-17(22)16-14-19-20(2,3)10-8-11-21(19,4)23-18(16)13-15/h12-13,19,22H,5-11,14H2,1-4H3/t19-,21+/m1/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 6.70E+3n/an/an/an/a



Universit£ di Napoli Federico II

Curated by ChEMBL


Assay Description
Agonist activity at rat TRPV3 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay


Bioorg Med Chem 26: 4532-4536 (2018)


Article DOI: 10.1016/j.bmc.2018.07.044
BindingDB Entry DOI: 10.7270/Q2M32ZFD
More data for this
Ligand-Target Pair