Compile Data Set for Download or QSAR

Found 2 hits of ki for UniProtKB: P17405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingomyelin phosphodiesterase (Homo sapiens)	BDBM50407246 (CHEMBL5279916) Show SMILES CC(C)C[C@@H]1CN[C@@H](CCC(=O)NCc2ccccc2)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@H](Cc2ccccc2)C(=O)NCCC(=O)N1 Show InChI InChI=1S/C46H59N9O7/c1-29(2)23-33-28-50-36(18-20-41(57)51-26-31-13-7-4-8-14-31)44(60)53-37(17-19-40(47)56)45(61)55-39(25-32-27-49-35-16-10-9-15-34(32)35)46(62)54-38(24-30-11-5-3-6-12-30)43(59)48-22-21-42(58)52-33/h3-16,27,29,33,36-39,49-50H,17-26,28H2,1-2H3,(H2,47,56)(H,48,59)(H,51,57)(H,52,58)(H,53,60)(H,54,62)(H,55,61)/t33-,36+,37-,38-,39+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars		530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Negative log concentration of antagonistic compound was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundus				Citation and Details
					More data for this Ligand-Target Pair
Sphingomyelin phosphodiesterase (Homo sapiens)	BDBM50520425 (CHEMBL4556453) Show SMILES CCCCCCCCCCCCC\C=C\[C@H](O)[C@@H](COP([O-])(=O)OCC[N+](C)(C)C)NC(=S)NC(C)(C)C |r| Show InChI InChI=1S/C28H58N3O5PS/c1-8-9-10-11-12-13-14-15-16-17-18-19-20-21-26(32)25(29-27(38)30-28(2,3)4)24-36-37(33,34)35-23-22-31(5,6)7/h20-21,25-26,32H,8-19,22-24H2,1-7H3,(H2-,29,30,33,34,38)/b21-20+/t25-,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of acid sphingomyelinase (unknown origin)				J Med Chem 63: 961-974 (2020) Article DOI: 10.1021/acs.jmedchem.9b00739 BindingDB Entry DOI: 10.7270/Q2FJ2M5M
					More data for this Ligand-Target Pair