Compile Data Set for Download or QSAR

Found 5 hits of ic50 for UniProtKB: P15384   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 3 (Rattus norvegicus)	BDBM50220547 (4,5-Dibromo-1H-pyrrole-2-carboxylic acid [3-(2-ami...) Show SMILES Nc1ncc(C=CCNC(=O)c2cc(Br)c(Br)[nH]2)[nH]1 |w:6.6| Show InChI InChI=1S/C11H11Br2N5O/c12-7-4-8(18-9(7)13)10(19)15-3-1-2-6-5-16-11(14)17-6/h1-2,4-5,18H,3H2,(H,15,19)(H3,14,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of rat Kv1.3 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assay				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Rattus norvegicus)	BDBM50456982 (CHEMBL4208517) Show SMILES Cc1[nH]c(C(=O)NC\C=C\c2c[nH]c(N)n2)c(Br)c1Br Show InChI InChI=1S/C12H13Br2N5O/c1-6-8(13)9(14)10(18-6)11(20)16-4-2-3-7-5-17-12(15)19-7/h2-3,5,18H,4H2,1H3,(H,16,20)(H3,15,17,19)/b3-2+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of rat Kv1.3 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assay				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Rattus norvegicus)	BDBM50456975 (CHEMBL4213446) Show SMILES Cc1[nH]c(cc1Br)C(=O)NC\C=C\c1c[nH]c(N)n1 Show InChI InChI=1S/C12H14BrN5O/c1-7-9(13)5-10(17-7)11(19)15-4-2-3-8-6-16-12(14)18-8/h2-3,5-6,17H,4H2,1H3,(H,15,19)(H3,14,16,18)/b3-2+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of rat Kv1.3 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assay				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Rattus norvegicus)	BDBM50456969 (CHEMBL4202870) Show SMILES Cc1[nH]c(cc1Cl)C(=O)NC\C=C\c1c[nH]c(N)n1 Show InChI InChI=1S/C12H14ClN5O/c1-7-9(13)5-10(17-7)11(19)15-4-2-3-8-6-16-12(14)18-8/h2-3,5-6,17H,4H2,1H3,(H,15,19)(H3,14,16,18)/b3-2+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of rat Kv1.3 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assay				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Rattus norvegicus)	BDBM50456976 (CHEMBL4207745) Show SMILES Nc1nc(\C=C\CNC(=O)c2cc(Cl)c(Cl)[nH]2)c[nH]1 Show InChI InChI=1S/C11H11Cl2N5O/c12-7-4-8(18-9(7)13)10(19)15-3-1-2-6-5-16-11(14)17-6/h1-2,4-5,18H,3H2,(H,15,19)(H3,14,16,17)/b2-1+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of rat Kv1.3 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assay				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
					More data for this Ligand-Target Pair