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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for UniProtKB: P02489   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-crystallin A chain


(Homo sapiens)		BDBM50459236
PNG
(CHEMBL4203007)
Show SMILES [H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@]1([H])CC3)[C@H](C)CCCC(C)(C)O |r,c:6|
Show InChI InChI=1S/C30H52O2/c1-20(10-9-16-26(2,3)32)21-13-18-30(8)23-11-12-24-27(4,5)25(31)15-17-28(24,6)22(23)14-19-29(21,30)7/h20-21,24-25,31-32H,9-19H2,1-8H3/t20-,21-,24+,25+,28-,29-,30+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 36n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Induction of redissolving of aggregated alpha-crystallin A Y118D mutant (unknown origin) incubated for 24 hrs by ThT-fluorescence based assay

J Med Chem 61: 8693-8706 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00705
BindingDB Entry DOI: 10.7270/Q2JQ13NZ
More data for this
Ligand-Target Pair