BindingDB PrimarySearch

Found 12 hits of ic50 for UniProtKB: P38417
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM50009001 (5,6,7-Trihydroxyflavone \| 5,6,7-trihydroxy-2-pheny...) Show SMILES Oc1cc2oc(cc(=O)c2c(O)c1O)-c1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86103 (3'-Hydroxyepiglucoisatisin, 3) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.06E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86102 (Epiglucoisatisin, 2) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.37E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86101 (2-[Cyano(3-indolyl) methylene]-3-indolone, 1) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.91E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86104 (Sulfoglucobrassicin, 4) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.19E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86105 (Isatan A, 5) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.93E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86106 (Isatan B, 6) Show SMILES OCC1OC(Oc2c[nH]c3ccccc23)C(O)C(=O)C1O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.38E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86026 (p-menth-3-ene-1,2-diol 1-O-B-glucopyranoside, 5) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+5	n/a	n/a	n/a	n/a	n/a	25
University of Athens					Assay Description soybean lipoxygenase and linoleic acid sodium salt were obtained from Sigma Chemical, Co. in St. Louis, MO. Each experiment of the in vitro assay wa...				J Enzyme Inhib Med Chem 22: 99-104 (2007) Article DOI: 10.1080/14756360600991017 BindingDB Entry DOI: 10.7270/Q22N50VW
University of Athens					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86025 (12-hydroxy-jasmonic acid 12-O-B-glucoside, 4) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60E+5	n/a	n/a	n/a	n/a	n/a	25
University of Athens					Assay Description soybean lipoxygenase and linoleic acid sodium salt were obtained from Sigma Chemical, Co. in St. Louis, MO. Each experiment of the in vitro assay wa...				J Enzyme Inhib Med Chem 22: 99-104 (2007) Article DOI: 10.1080/14756360600991017 BindingDB Entry DOI: 10.7270/Q22N50VW
University of Athens					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM4375 ((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid \| (2...) Show SMILES OC(=O)\C=C\c1ccc(O)c(O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a	25
University of Athens					Assay Description soybean lipoxygenase and linoleic acid sodium salt were obtained from Sigma Chemical, Co. in St. Louis, MO. Each experiment of the in vitro assay wa...				J Enzyme Inhib Med Chem 22: 99-104 (2007) Article DOI: 10.1080/14756360600991017 BindingDB Entry DOI: 10.7270/Q22N50VW
University of Athens					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86024 (Lithospermic acid, 3) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	25
University of Athens					Assay Description soybean lipoxygenase and linoleic acid sodium salt were obtained from Sigma Chemical, Co. in St. Louis, MO. Each experiment of the in vitro assay wa...				J Enzyme Inhib Med Chem 22: 99-104 (2007) Article DOI: 10.1080/14756360600991017 BindingDB Entry DOI: 10.7270/Q22N50VW
University of Athens					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM50133496 ((2R)-3-(3,4-dihydroxyphenyl)-2-[(2E)-3-(3,4-dihydr...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.15E+6	n/a	n/a	n/a	n/a	n/a	25
University of Athens					Assay Description soybean lipoxygenase and linoleic acid sodium salt were obtained from Sigma Chemical, Co. in St. Louis, MO. Each experiment of the in vitro assay wa...				J Enzyme Inhib Med Chem 22: 99-104 (2007) Article DOI: 10.1080/14756360600991017 BindingDB Entry DOI: 10.7270/Q22N50VW
University of Athens					More data for this Ligand-Target Pair