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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for UniProtKB: P00492   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxanthine-guanine phosphoribosyltransferase


(Homo sapiens (Human))
BDBM50438479
PNG
(CHEMBL2414636)
Show SMILES OC[C@H](CCP(O)(O)=O)NCc1c[nH]c2c1nc[nH]c2=O |r|
Show InChI InChI=1S/C11H17N4O5P/c16-5-8(1-2-21(18,19)20)12-3-7-4-13-10-9(7)14-6-15-11(10)17/h4,6,8,12-13,16H,1-3,5H2,(H,14,15,17)(H2,18,19,20)/t8-/m0/s1
PDB
MMDB

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CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 385n/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human HGPRT by Morrison method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02184
BindingDB Entry DOI: 10.7270/Q26D5XRJ
More data for this
Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase


(Homo sapiens (Human))
BDBM50438487
PNG
(CHEMBL2414703)
Show SMILES OP(O)(=O)CCCNCc1c[nH]c2c1nc[nH]c2=O
Show InChI InChI=1S/C10H15N4O4P/c15-10-9-8(13-6-14-10)7(5-12-9)4-11-2-1-3-19(16,17)18/h5-6,11-12H,1-4H2,(H,13,14,15)(H2,16,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 4.94E+3n/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human HGPRT by Morrison method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02184
BindingDB Entry DOI: 10.7270/Q26D5XRJ
More data for this
Ligand-Target Pair