Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isoform 1 of Metabotropic glutamate receptor 5 (5a) (Rattus norvegicus (Rat)) | BDBM143695 (US9682959, 3 | US9751856, 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description The pharmacological activity of the compounds was tested using the following method: cDNA encoding rat mGlu 5a receptor was transiently transfected i... | US Patent US9751856 (2017) BindingDB Entry DOI: 10.7270/Q2G162ZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 1 of Metabotropic glutamate receptor 5 (5a) (Rattus norvegicus (Rat)) | BDBM143693 (US9682959, 1 | US9751856, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description The pharmacological activity of the compounds was tested using the following method: cDNA encoding rat mGlu 5a receptor was transiently transfected i... | US Patent US9751856 (2017) BindingDB Entry DOI: 10.7270/Q2G162ZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 1 of Metabotropic glutamate receptor 5 (5a) (Rattus norvegicus (Rat)) | BDBM143694 (US9682959, 2 | US9751856, 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description The pharmacological activity of the compounds was tested using the following method: cDNA encoding rat mGlu 5a receptor was transiently transfected i... | US Patent US9751856 (2017) BindingDB Entry DOI: 10.7270/Q2G162ZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 1 of Metabotropic glutamate receptor 5 (5a) (Rattus norvegicus (Rat)) | BDBM143697 (US9682959, 4 | US9751856, 4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description The pharmacological activity of the compounds was tested using the following method: cDNA encoding rat mGlu 5a receptor was transiently transfected i... | US Patent US9751856 (2017) BindingDB Entry DOI: 10.7270/Q2G162ZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 1 of Metabotropic glutamate receptor 5 (5a) (Rattus norvegicus (Rat)) | BDBM143699 (US9682959, 6 | US9751856, 6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description The pharmacological activity of the compounds was tested using the following method: cDNA encoding rat mGlu 5a receptor was transiently transfected i... | US Patent US9751856 (2017) BindingDB Entry DOI: 10.7270/Q2G162ZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 1 of Metabotropic glutamate receptor 5 (5a) (Rattus norvegicus (Rat)) | BDBM143698 (US9682959, 5 | US9751856, 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 281 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description The pharmacological activity of the compounds was tested using the following method: cDNA encoding rat mGlu 5a receptor was transiently transfected i... | US Patent US9751856 (2017) BindingDB Entry DOI: 10.7270/Q2G162ZZ | |||||||||||
More data for this Ligand-Target Pair |