Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Galectin-3 (Homo sapiens (Human)) | BDBM653576 (3-[4-(4-Chloro-3,5-difluorophenyl)-1H-1,2,3-triazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM653575 (3,3′-Dideoxy-3-[4-(3,4,5-trifluorophenyl)-1H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM653577 (3′-[4-(2-Aminothiazol-4-yl)-1H-1,2,3-triazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM455404 (3,3′-Dideoxy-3-[4-(tetrahydropyran-4-yl)-1H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
GALECTO BIOTECH AB US Patent | Assay Description The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter... | US Patent US10730902 (2020) BindingDB Entry DOI: 10.7270/Q2VD72HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM468290 (3-{4-[(Butylamino)carbonyl]-1H-1,2,3-triazol-1-yl}...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use... | US Patent US10800804 (2020) BindingDB Entry DOI: 10.7270/Q2H70JWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM468295 (3,3′-Dideoxy-3,3′-di-[4-(3-fluoropheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use... | US Patent US10800804 (2020) BindingDB Entry DOI: 10.7270/Q2H70JWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM468297 (US10800804, Example 3b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in... | US Patent US10800804 (2020) BindingDB Entry DOI: 10.7270/Q2H70JWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247478 (CHEMBL4066068) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM468295 (3,3′-Dideoxy-3,3′-di-[4-(3-fluoropheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use... | US Patent US10800804 (2020) BindingDB Entry DOI: 10.7270/Q2H70JWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247479 (CHEMBL4104417) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247477 (CHEMBL4102995) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247477 (CHEMBL4102995) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxybenzamido)-1,1'-sulfanediyl-di-beta-... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247478 (CHEMBL4066068) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxybenzamido)-1,1'-sulfanediyl-di-beta-... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247479 (CHEMBL4104417) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Binding affinity to human galectin 3 C-terminal domain expressed in Escherichia coli BL21(DE3) by competitive isothermal titration calorimetric analy... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM560370 (3,4-Dichlorophenyl 3- deoxy-3-[4-(2,3,4,5,6- penta...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The assay was adapted to be able to measure the high affinity of compounds for galectin-3 by using the below probe constructed to have high affinity ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2T72MPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM455401 (3,3'-Dideoxy-3- [4-(morpholin-4- yl)-1H-1,2,3- tri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a |
GALECTO BIOTECH AB US Patent | Assay Description The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter... | US Patent US10730902 (2020) BindingDB Entry DOI: 10.7270/Q2VD72HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM455405 (3,3′-Dideoxy-3-[4-(propan-2-yl)-1H-1,2,3-tri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a |
GALECTO BIOTECH AB US Patent | Assay Description The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter... | US Patent US10730902 (2020) BindingDB Entry DOI: 10.7270/Q2VD72HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM468288 (3′-Deoxy-3-O-[(5,6-difluoro-2-oxo-3-chromeny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use... | US Patent US10800804 (2020) BindingDB Entry DOI: 10.7270/Q2H70JWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM468298 (US10800804, Example 3c) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in... | US Patent US10800804 (2020) BindingDB Entry DOI: 10.7270/Q2H70JWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM461847 (3,4-Dichlorophenyl 3-deoxy-3-[4-(2,3,4,5,6-pentafl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a |
Galecto Biotech AB US Patent | Assay Description The affinity of Example 1-106 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the int... | US Patent US10774102 (2020) BindingDB Entry DOI: 10.7270/Q20P133G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247476 (CHEMBL4091143) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247479 (CHEMBL4104417) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxybenzamido)-1,1'-sulfanediyl-di-beta-... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247476 (CHEMBL4091143) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxybenzamido)-1,1'-sulfanediyl-di-beta-... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247482 (CHEMBL4065371) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247477 (CHEMBL4102995) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Binding affinity to human galectin 3 C-terminal domain expressed in Escherichia coli BL21(DE3) by competitive isothermal titration calorimetric analy... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50591134 (CHEMBL5181494) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00660 BindingDB Entry DOI: 10.7270/Q2V69PJ9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM468294 (3,3′-Dideoxy-3-[4-(3,4,5-trifluorophenyl)-1H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use... | US Patent US10800804 (2020) BindingDB Entry DOI: 10.7270/Q2H70JWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM468296 (3,3′-dideoxy-3,3′-di-[4-(3,4-difluorop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in... | US Patent US10800804 (2020) BindingDB Entry DOI: 10.7270/Q2H70JWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247478 (CHEMBL4066068) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Binding affinity to human galectin 3 C-terminal domain expressed in Escherichia coli BL21(DE3) by competitive isothermal titration calorimetric analy... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247480 (CHEMBL4064035) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247482 (CHEMBL4065371) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxybenzamido)-1,1'-sulfanediyl-di-beta-... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM455403 (3,3′-Dideoxy-3-[4-(piperidin-4-yl)-1H-1,2,3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a |
GALECTO BIOTECH AB US Patent | Assay Description The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter... | US Patent US10730902 (2020) BindingDB Entry DOI: 10.7270/Q2VD72HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM572517 (5-Bromo-2-(N-azetidinylcarbamoyl)-3-pyridyl 3-deox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The affinity of Example 1-71 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B1J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM653579 (1,1′-Sulfanediyl-bis-{3-deoxy-3-[4-(3,4,5-tr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM572496 (2-(N-azetidinyl-carbonyl)-5-chlorophenyl 3-deoxy-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The affinity of Example 1-71 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B1J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM468291 (3,3′-Dideoxy-3′-[4-(3-fluorophenyl)-1H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use... | US Patent US10800804 (2020) BindingDB Entry DOI: 10.7270/Q2H70JWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM455402 (3,3′-Dideoxy-3-[4-(4-methylpiperazin-1-yl)-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a |
GALECTO BIOTECH AB US Patent | Assay Description The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter... | US Patent US10730902 (2020) BindingDB Entry DOI: 10.7270/Q2VD72HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM572516 (5-Bromo-2-(N-azetidinylcarbamoyl)-3-pyridyl 3-[4-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The affinity of Example 1-71 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B1J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM572518 (5-Bromo-2-(N-azetidinylcarbamoyl)-3-pyridyl 3-[4-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The affinity of Example 1-71 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B1J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM572462 (4-Chloro-N,N- dimethyl-benzamide-2- yl 3-deoxy-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The affinity of Example 1-71 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B1J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247475 (CHEMBL4071878) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.70 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Binding affinity to human galectin-3 expressed in Escherichia coli BL21(DE3) in presence of BSA by direct fluorescence polarization titration assay | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247476 (CHEMBL4091143) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.70 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Binding affinity to human galectin 3 C-terminal domain expressed in Escherichia coli BL21(DE3) by competitive isothermal titration calorimetric analy... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM653578 (1,1′-Sulfanediyl-bis-{3-deoxy-3-[4-(3-fluoro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM461829 (3,4-Dichlorophenyl 3-deoxy-3-[4-(3,4,5-trifluoroph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
Galecto Biotech AB US Patent | Assay Description The affinity of Example 1-106 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the int... | US Patent US10774102 (2020) BindingDB Entry DOI: 10.7270/Q20P133G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM560352 (3,4-Dichlorophenyl 3-deoxy-3-[4-(3,4,5-trifluoroph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The assay was adapted to be able to measure the high affinity of compounds for galectin-3 by using the below probe constructed to have high affinity ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2T72MPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM572521 (5-Chloro-2-(N-azetidinylcarbamoyl)-3-pyridyl 3-[4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The affinity of Example 1-71 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B1J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM572524 (5-Chloro-2-(N-azetidinylcarbamoyl)-3-pyridyl 3-[4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The affinity of Example 1-71 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B1J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM50247480 (CHEMBL4064035) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Binding affinity to human galectin 3 C-terminal domain expressed in Escherichia coli BL21(DE3) by competitive isothermal titration calorimetric analy... | J Med Chem 61: 1164-1175 (2018) Article DOI: 10.1021/acs.jmedchem.7b01626 BindingDB Entry DOI: 10.7270/Q2794743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM478066 (5-Chloro-2-cyano-3-pyridyl 3-deoxy-3-[4-(4-chloro-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a |
GALECTO BIOTECH AB US Patent | Assay Description The affinity of Example 1-22 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte... | US Patent US10889610 (2021) BindingDB Entry DOI: 10.7270/Q2BK1GG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM478064 (5-Bromo-2-cyano-3-pyridyl 3-deoxy-3-[4-(4-chloro-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a |
GALECTO BIOTECH AB US Patent | Assay Description The affinity of Example 1-22 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte... | US Patent US10889610 (2021) BindingDB Entry DOI: 10.7270/Q2BK1GG1 | |||||||||||
More data for this Ligand-Target Pair |
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